Gene Dsec\Obp99a

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General Information

Symbol

Dsec\Obp99a

Species

D. sechellia

Name

Odorant-binding protein 99a

Annotation symbol

GM12800

Feature type

protein_coding_gene

FlyBase ID

FBgn0263699

Gene Model Status

Current

Stock availability

None publicly available

Also Known As

Obp99a, dsec_GLEANR_13178

Genomic Location

Chromosome (arm)

scaffold_4

Recombination map

Cytogenetic map

Sequence location

scaffold_4:4,352,231..4,352,727 [+]

Genomic Maps

Summary Information

Automatically generated summary

See sections below for more information

The gene Odorant-binding protein 99a is referred to in FlyBase by the symbol Dsec\Obp99a (GM12800, FBgn0263699). It is a protein_coding_gene from Drosophila sechellia. An electronic pipeline based on InterPro domains suggests that it has the molecular function: odorant binding. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide. Protein features are: Pheromone/general odorant binding protein; Pheromone/general odorant binding protein, PBP/GOBP, domain. Gene sequence location is scaffold_4:4352231..4352727.

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dsec\Obp99a for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Dsec\Obp99a-RA

FBtr0195785

XM_002037181

429

142

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Dsec\Obp99a-PA

FBpp0194277

16.0

142

6.34

XP_002037217

EDW53376

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Pheromone/general odorant binding protein (IPR006170)

Pheromone/general odorant binding protein, PBP/GOBP, domain (IPR023316)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

B4HZB9

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

modENCODE Anatomy RNA-Seq

modENCODE Development RNA-Seq

modENCODE Cell Lines RNA-Seq

modENCODE Treatments RNA-Seq

Expression Clusters

External Data & Images

Linkouts

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of Dsec\Obp99a	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Dsec\Obp99a	Class	Mutagen	Stocks	Known lesion

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 1 term )

Molecular Function

CV term

Evidence

References

odorant binding

inferred from electronic annotation with InterPro:IPR006170, InterPro:IPR006625

(FlyBase Curators et al., 2004-)

Biological Process ( 0 terms)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

gene

(Dworkin and Jones, 2009)

nuclear_gene

(Drosophila 12 Genomes Consortium, 2008)

protein_coding_gene

(Drosophila 12 Genomes Consortium, 2008)

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

Dsec\Obp99a allele

Gene

References

External Data

Linkouts

Orthologs

OrthoDB Orthologs (1) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG63V0G3

Dipteran inclusive ortholog search

No orthologs identified

Insect inclusive ortholog search

EOG67D8CS

Arthropod inclusive ortholog search

No orthologs identified

Metazoa inclusive ortholog search

No orthologs identified

Ortholog(s) in Drosophila melanogaster (EOG63V0G3)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\Obp99a

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (1) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila melanogaster

Dmel\Obp99a

Stocks & Reagents

Stocks Listed in FlyBase ( 0 )

Genomic Clones ( 0 )

cDNA Clones ( 0 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: Dsec\Obp99a Dsec\GM12800

(Vieira and Rozas, 2011)

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

XM_002037181

RefSeq (Proteins)

•

XP_002037217

DDBJ / EMBL / GenBank

•

EDW53376

Entrez Gene - A searchable database of RefSeq genes.

•

6612714

UniProtKB/TrEMBL

•

B4HZB9

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Pheromone/general odorant binding protein (IPR006170)

Pheromone/general odorant binding protein, PBP/GOBP, domain (IPR023316)

Linkouts

Synonyms & Secondary IDs ( 7 )

Reported As

Symbol Synonym

dsec_GLEANR_13178

(Vieira and Rozas, 2011, Drosophila 12 Genomes Consortium, 2008)

Dsec\GM12800

(Drosophila 12 Genomes Consortium, 2008)

Dsec\Obp99a

DsecObp99a

(Vieira and Rozas, 2011)

GM12800

(Drosophila 12 Genomes Consortium, 2008)

Obp99a

(Rebeiz et al., 2011, Dworkin and Jones, 2009)

Name Synonym

Odorant-binding protein 99a

Secondary FlyBase IDs

FBgn0167736
FBgn0261183

References ( 7 )

Research paper

Rebeiz et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(25): 10036--10043: Evolutionary origin of a novel gene expression pattern through co-option of the latent activities of existing regulatory sequences. [FBrf0214016]
Vieira and Rozas, 2011, Genome Biol. Evol. 3: 476--490: Comparative Genomics of the Odorant-Binding and Chemosensory Protein Gene Families across the Arthropoda: Origin and Evolutionary History of the Chemosensory System. [FBrf0214323]
Dworkin and Jones, 2009, Genetics 181(2): 721--736: Genetic Changes Accompanying the Evolution of Host Specialization in Drosophila sechellia. [FBrf0207106]
Drosophila 12 Genomes Consortium et al., 2007, Nature 450(7167): 203--218: Evolution of genes and genomes on the Drosophila phylogeny. [FBrf0200326]

Supplementary material

Vieira and Rozas, 2011, Genome Biol. Evol. 3:: Supplementary Data 1. OBP protein sequences in FASTA format. [FBrf0216366]

Personal communication to FlyBase

Drosophila 12 Genomes Consortium, 2008, personal communication to FlyBase: Symbols and class of gene information for the GLEANR consensus sequences of the 11 sequenced non-melanogaster Drosophila species (Drosophila ananassae, erecta, grimshawi, mojavensis, persimilis, pseudoobscura, sechellia, simulans, willistoni, virilis and yakuba). [FBrf0202436]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]