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Gene Dmel\jvl

General Information
Symbol	Dmel\jvl	Species	D. melanogaster
Name	javelin-like	Annotation symbol	CG43162
Feature type	protein_coding_gene	FlyBase ID	FBgn0263929
Gene Model Status	Current	Stock availability	22 publicly available
Also Known As	CG3563
Genomic Location
Chromosome (arm)	3R	Recombination map	3-56.7
Cytogenetic map	88D3-88E3	Sequence location	3R:10,567,309..10,621,590 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene javelin-like is referred to in FlyBase by the symbol Dmel\jvl (CG43162, FBgn0263929). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: RNA localization; actin filament bundle assembly; oocyte microtubule cytoskeleton organization; oocyte nucleus localization involved in oocyte dorsal/ventral axis specification; chaeta morphogenesis; oocyte growth in germarium-derived egg chamber; dorsal appendage formation; oocyte localization involved in germarium-derived egg chamber formation. 19 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; egg; oocyte; macrochaeta; microtubule cytoskeleton; microchaeta; actin cytoskeleton; oocyte nucleus. It has 7 annotated transcripts and 7 annotated polypeptides. Gene sequence location is 3R:10567309..10621590.
User Contributed Data
	Beta version, feedback welcome
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	jvl: javelinlike Resembles jv but bristles sometimes more crooked. Viability and productivity somewhat lower than normal. RK2.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03	Alleles jvl[MI07819]
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 88D3-88E3   Limits computationally determined from genome sequence between P{EP}CG33967EP666 and P{lacW}Hsc70-4L3929; Left limit from recombination mapping relative to wrl (FBrf0051995) Right limit from inclusion within Tp(3;1)kar5l (FBrf0051995)
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	3-56.7
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\jvl for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene merge based on EST/cDNA and RNAseq data.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) jvl-RA FBtr0305690  NM_142132   6431   1153 jvl-RB FBtr0305689  NM_206488   3237   959 jvl-RC FBtr0305691  NM_001104323   3855   958 jvl-RD FBtr0305692  NM_001260176   5345   1315 jvl-RE FBtr0305693  NM_001260177   4959   958 jvl-RF FBtr0305694  NM_001260178   6488   1151 jvl-RG FBtr0305695  NM_001260179   4513   1120
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein jvl-PA   FBpp0296970   122.5   1153   9.90     NP_650389   AAF55097 jvl-PB   FBpp0296969   102.5   959   10.23     NP_996210   AAS65152 jvl-PC   FBpp0296971   102.4   958   10.23     NP_001097793   ABW08675 jvl-PD   FBpp0296972   141.0   1315   6.91     NP_001247105   AFH06423 jvl-PE   FBpp0296973   102.4   958   10.23     NP_001247106   AFH06424 jvl-PF   FBpp0296974   122.3   1151   9.87     NP_001247107   AFH06425 jvl-PG   FBpp0296975   120.9   1120   6.89     NP_001247108   AFH06426
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201665   AA202000   AA264183   AA264217   AA392147   AA439424   AA440807   AA441150   AA735116   AA816307   AA816321   AA817055   AA940669   AA950844   AE014297 AAF55097   AE014297 AAS65152   AE014297 ABW08675   AE014297 AFH06423   AE014297 AFH06424   AE014297 AFH06425   AE014297 AFH06426   AI259038   AI511995   AI514718   AI515816   AI518237   AI519538   AI520540   AW943566   AX201620   AX201621   AY051933 AAK93357   BF491442   BG637902   BG637905   BG638290   BI238122   BI242273   BI569542   BI637244   BI640599   BP540630   BP540631   BP540718   BP540719   BQ103529   BT011377   BT022817   BT050532   BT100189   BT100217   CK086527   CO157073   CO185778   CO188053   CO188092   CO272276   CO272374   CO277024   CO278659   CO280965   CO283312   CO285641   CO286929   CO292479   CO295331   CO299363   CO301010   CO303155   CO305833   CO308296   CO309864   CO311241   CO315661   CO315806   CO319897   CO320884   CO323859   CO324274   CO329174   CO330389   CO336448   CO337273   CZ468430   CZ468431   CZ478966   CZ479046   CZ479047   CZ480537   CZ483049   CZ483050   CZ483173   EC061232   EC064779   EC066327   EC067095   EC073156   EC075939   EC077035   EC077036   EC077419   EC078942   EC083115   EC195228   EC198726   EC200173   EC202390   EC208392   EC209225   EC212993   EC221373   EC222596   EC226479   EC229218   EC229668   EC232082   EC232333   EC233979   EC235239   EC235588   EC237616   EC238402   EC239282   EC240528   EC243354   EC244740   EC246012   EC248307   EC249564   EC266736   EC267804   FL502840
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7KSJ6 Q9VFG3 Q6NNB4 Q7KSJ5 Q960P5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
microtubule cytoskeleton inferred from direct assay (Dubin-Bar et al., 2011)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    13 central nervous system, pupae P8    19 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    85 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    6 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    29 ovary, mated 4-day female    27 testis, mated 4-day male    13 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    13 central nervous system, pupae P8    19 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae  (85) digestive system, larvae L3 wandering    10 digestive system, 1-day adult    6 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female  (29) ovary, mated 4-day female  (27) testis, mated 4-day male    13 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    13 central nervous system, pupae P8    19 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    85 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    6 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    29 ovary, mated 4-day female    27 testis, mated 4-day male    13 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    13 central nervous system, pupae P8    19 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    85 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    6 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    29 ovary, mated 4-day female    27 testis, mated 4-day male    13 accessory gland, mated 4-day male    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    13 central nervous system, pupae P8    19 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    85 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    6 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    29 ovary, mated 4-day female    27 testis, mated 4-day male    13 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    13 central nervous system, pupae P8    19 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae  (85) digestive system, larvae L3 wandering    10 digestive system, 1-day adult    6 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female  29 ovary, mated 4-day female  27 testis, mated 4-day male    13 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    13 central nervous system, pupae P8    19 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    85 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    6 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    29 ovary, mated 4-day female    27 testis, mated 4-day male    13 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    21 central nervous system, larvae L3    13 central nervous system, pupae P8    19 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    7 head, mated 1-day female    7 head, mated 4-day female    7 head, mated 20-day female    7 head, mated 1-day male    13 head, mated 4-day male    12 head, mated 20-day male    12 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    85 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    6 digestive system, 4-day adult    8 digestive system, 20-day adult    9 fat body, larvae L3 wandering    4 fat body, white prepupae    12 fat body, pupae P8    9 carcass, larvae L3 wandering    11 carcass, 1-day adult    5 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    29 ovary, mated 4-day female    27 testis, mated 4-day male    13 accessory gland, mated 4-day male    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    22 embryo 04-06hr    17 embryo 06-08hr    15 embryo 08-10hr    17 embryo 10-12hr    11 embryo 12-14hr    15 embryo 14-16hr    20 embryo 16-18hr    16 embryo 18-20hr    12 embryo 20-22hr    15 embryo 22-24hr    14 larva L1    5 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    12 white prepupae new    17 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    9 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    12 adult female 05day    19 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (30) embryo 02-04hr    22 embryo 04-06hr    17 embryo 06-08hr    15 embryo 08-10hr    17 embryo 10-12hr    11 embryo 12-14hr    15 embryo 14-16hr    20 embryo 16-18hr    16 embryo 18-20hr    12 embryo 20-22hr    15 embryo 22-24hr    14 larva L1    5 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    12 white prepupae new    17 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    9 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    12 adult female 05day    19 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    22 embryo 04-06hr    17 embryo 06-08hr    15 embryo 08-10hr    17 embryo 10-12hr    11 embryo 12-14hr    15 embryo 14-16hr    20 embryo 16-18hr    16 embryo 18-20hr    12 embryo 20-22hr    15 embryo 22-24hr    14 larva L1    5 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    12 white prepupae new    17 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    9 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    12 adult female 05day    19 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    22 embryo 04-06hr    17 embryo 06-08hr    15 embryo 08-10hr    17 embryo 10-12hr    11 embryo 12-14hr    15 embryo 14-16hr    20 embryo 16-18hr    16 embryo 18-20hr    12 embryo 20-22hr    15 embryo 22-24hr    14 larva L1    5 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    12 white prepupae new    17 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    9 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    12 adult female 05day    19 adult female 30day    20 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    22 embryo 04-06hr    17 embryo 06-08hr    15 embryo 08-10hr    17 embryo 10-12hr    11 embryo 12-14hr    15 embryo 14-16hr    20 embryo 16-18hr    16 embryo 18-20hr    12 embryo 20-22hr    15 embryo 22-24hr    14 larva L1    5 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    12 white prepupae new    17 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    9 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    12 adult female 05day    19 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  30 embryo 02-04hr    22 embryo 04-06hr    17 embryo 06-08hr    15 embryo 08-10hr    17 embryo 10-12hr    11 embryo 12-14hr    15 embryo 14-16hr    20 embryo 16-18hr    16 embryo 18-20hr    12 embryo 20-22hr    15 embryo 22-24hr    14 larva L1    5 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    12 white prepupae new    17 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    9 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    12 adult female 05day    19 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    22 embryo 04-06hr    17 embryo 06-08hr    15 embryo 08-10hr    17 embryo 10-12hr    11 embryo 12-14hr    15 embryo 14-16hr    20 embryo 16-18hr    16 embryo 18-20hr    12 embryo 20-22hr    15 embryo 22-24hr    14 larva L1    5 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    12 white prepupae new    17 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    9 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    12 adult female 05day    19 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    30 embryo 02-04hr    22 embryo 04-06hr    17 embryo 06-08hr    15 embryo 08-10hr    17 embryo 10-12hr    11 embryo 12-14hr    15 embryo 14-16hr    20 embryo 16-18hr    16 embryo 18-20hr    12 embryo 20-22hr    15 embryo 22-24hr    14 larva L1    5 larva L2    6 larva L3 12hr old    5 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    8 larva L3 puffstage 7-9    12 white prepupae new    17 white prepupae 12hr    18 white prepupae 24hr    15 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    9 adult male 01day    9 adult male 05day    11 adult male 30day    10 adult female 01day    12 adult female 05day    19 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    4 embryonic 1182-4H    10 embryonic GM2    11 embryonic Kc167    5 embryonic S1    9 embryonic S3    7 leg disc CME L1    5 wing disc CME-W2    6 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    4 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    14 eye-antennal disc ML-DmD11    7 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    7 ovary fGS/OSS    16 ovary OSC    16 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    4 embryonic 1182-4H    10 embryonic GM2    11 embryonic Kc167    5 embryonic S1    9 embryonic S3    7 leg disc CME L1    5 wing disc CME-W2    6 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    4 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    14 eye-antennal disc ML-DmD11    7 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    7 ovary fGS/OSS    16 ovary OSC    16 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    4 embryonic 1182-4H    10 embryonic GM2    11 embryonic Kc167    5 embryonic S1    9 embryonic S3    7 leg disc CME L1    5 wing disc CME-W2    6 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    4 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    14 eye-antennal disc ML-DmD11    7 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    7 ovary fGS/OSS    16 ovary OSC    16 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    4 embryonic 1182-4H    10 embryonic GM2    11 embryonic Kc167    5 embryonic S1    9 embryonic S3    7 leg disc CME L1    5 wing disc CME-W2    6 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    4 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    14 eye-antennal disc ML-DmD11    7 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    7 ovary fGS/OSS    16 ovary OSC    16 ovary OSS    9 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    4 embryonic 1182-4H    10 embryonic GM2    11 embryonic Kc167    5 embryonic S1    9 embryonic S3    7 leg disc CME L1    5 wing disc CME-W2    6 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    4 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    14 eye-antennal disc ML-DmD11    7 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    7 ovary fGS/OSS    16 ovary OSC    16 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    4 embryonic 1182-4H    10 embryonic GM2    11 embryonic Kc167    5 embryonic S1    9 embryonic S3    7 leg disc CME L1    5 wing disc CME-W2    6 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    4 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    14 eye-antennal disc ML-DmD11    7 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    7 ovary fGS/OSS    16 ovary OSC    16 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    4 embryonic 1182-4H    10 embryonic GM2    11 embryonic Kc167    5 embryonic S1    9 embryonic S3    7 leg disc CME L1    5 wing disc CME-W2    6 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    4 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    14 eye-antennal disc ML-DmD11    7 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    7 ovary fGS/OSS    16 ovary OSC    16 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    6 Schneider line 2 Sg4    4 embryonic 1182-4H    10 embryonic GM2    11 embryonic Kc167    5 embryonic S1    9 embryonic S3    7 leg disc CME L1    5 wing disc CME-W2    6 wing disc ML-DmD8    10 wing disc ML-DmD9    10 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    4 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    14 eye-antennal disc ML-DmD11    7 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    6 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    7 ovary fGS/OSS    16 ovary OSC    16 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    12 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    12 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    12 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    12 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    12 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    12 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    12 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    12 heat shock, 4-day adult    11 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    24 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    13 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    24 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    18 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    17 Paraquat 10 mM 48 hrs, 4-day adult    18 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pharate adult stage (with Df(3R)Exel6275) jvlf00590 viable, with Scer\GAL4pnr-MD237 jvlGD11011 jvlGD16062 viable | reduced jvl1 Sterility Allele female fertile jvl1 female sterile (with Df(3R)Exel6275) jvl1 female sterile (with jvl1) jvlf00590 female sterile (with jvlf00590) jvl1 fertile | reduced jvl1 male fertile jvl1 Other Phenotypes Allele visible jvl1 visible, with Scer\GAL4pnr-MD237 jvlGD11011 Phenotype manifest in Allele actin cytoskeleton (with Df(3R)Exel6275) jvl1 egg (with Df(3R)Exel6275) jvl1 egg (with jvl1) jvlf00590 egg (with jvlf00590) jvl1 macrochaeta jvl1 macrochaeta, with Scer\GAL4neur-P72 jvlGD11011 macrochaeta (with Df(3R)Exel6275) jvl1 macrochaeta (with jvl1) jvlf00590 macrochaeta (with jvlf00590) jvl1 microchaeta jvl1 microchaeta & actin filament jvl1 microtubule cytoskeleton (with Df(3R)Exel6275) jvl1 oocyte, with Scer\GAL4mat.αTub67C.T:Hsim\VP16 jvlRA.Scer\UAS.P\T.T:Avic\GFP oocyte nucleus, with Scer\GAL4nos.UTR.T:Hsim\VP16 jvlRA.Scer\UAS.P\T.T:Avic\GFP trichogen cell, with Scer\GAL4pnr-MD237 jvlGD11011
Classical Alleles ( 15 )
For All Classical Alleles Show
Allele of jvl Class Mutagen Stocks Known lesion jvl1 spontaneous 6 Yes jvlf00590 hypomorphic allele - genetic evidence piggyBac transposase 2 -- jvlc03106 piggyBac transposase 1 -- jvlCB-0316-3 1 -- jvld00012 1 -- jvle02766 piggyBac transposase 1 -- jvlMB08021 1 -- jvlMI00961 1 -- jvlMI05061 1 -- jvlMI05568 1 -- jvlBG02490 P-element activity 0 -- jvle01153 piggyBac transposase 0 -- jvle01235 piggyBac transposase 0 -- jvlf00703 piggyBac transposase 0 -- jvlMI07819 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of jvl Class Mutagen Stocks Known lesion jvlGD11011 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes jvlGD16062 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes jvlGL01520 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes jvlKK104198 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes jvlRA.Scer\UAS.P\T.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Not disrupted in	Df(3R)c(3)G-2 (Nelson and Szauter, 1992) Df(3R)Po2 (Nelson and Szauter, 1992) Df(3R)Po3 (Nelson and Szauter, 1992) Df(3R)Po4 (Nelson and Szauter, 1992) Df(3R)red3l (Green et al., 1990)
Not duplicated in	Dp(3;2)ry+ (Green et al., 1990)
Duplicated in	Dp(3;1)O5
Disrupted in	Df(3R)Exel6275 (Ryder, 2004.4.26) Df(3R)Exel8160 (Ryder, 2004.4.26) Df(3R)kar5l (Green et al., 1990)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{TRiP.GL01520} NA P{UASp-jvl.RA.GFP} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}jvlMI00961 NA Mi{MIC}jvlMI05061 NA Mi{MIC}jvlMI05568 NA Mi{MIC}jvlMI07819 NA P{GT1}jvlBG02490 NA P{RS3}jvlCB-0316-3 NA PBac{PB}jvlc03106 NA PBac{RB}jvle01153 NA PBac{RB}jvle01235 NA PBac{RB}jvle02766 NA PBac{WH}jvlf00590 NA PBac{WH}jvlf00703 NA insertion of mobile activating element P{GSV1}EP-536EP-536 NA P{XP}jvld00012 NA insertion of enhancer trap binary system Mi{ET1}jvlMB08021 No
Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )
	There is no information supporting a molecular function term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 9 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
actin filament bundle assembly inferred from mutant phenotype (Tilney et al., 2003) chaeta morphogenesis inferred from mutant phenotype (Dubin-Bar et al., 2011) dorsal appendage formation inferred from mutant phenotype (Dubin-Bar et al., 2011) oocyte growth in germarium-derived egg chamber inferred from mutant phenotype (Dubin-Bar et al., 2011) oocyte localization involved in germarium-derived egg chamber formation inferred from mutant phenotype (Dubin-Bar et al., 2011) oocyte microtubule cytoskeleton organization inferred from mutant phenotype (Dubin-Bar et al., 2011) oocyte nucleus localization involved in oocyte dorsal/ventral axis specification inferred from mutant phenotype (Dubin-Bar et al., 2011) RNA localization inferred from mutant phenotype (Dubin-Bar et al., 2011)
Cellular Component
CV term Evidence References
microtubule cytoskeleton inferred from direct assay (Dubin-Bar et al., 2011)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
jvl - spn-F two hybrid, pull down, anti tag western blot (Dubin-Bar et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions jvl allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (25) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG68GWNX Dipteran inclusive ortholog search EOG66HGKP Insect inclusive ortholog search EOG6VX118 Arthropod inclusive ortholog search EOG6G1JXH Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG68GWNX)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\jvl     Drosophila simulans   Dsim\GD18973 Y   Drosophila sechellia   Dsec\GM24181 Y   Drosophila erecta   Dere\GG16872 Y   Drosophila yakuba   Dyak\GE24252 Y   Drosophila ananassae   Dana\GF16890 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17521 Y   Drosophila persimilis   Dper\GL23845 Y   Drosophila willistoni   Dwil\GK11399 Y   Drosophila mojavensis   Dmoj\GI22132 Y
Orthologs in non-Drosophila Dipterans (EOG66HGKP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003604   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ019219
Orthologs in non-Dipteran Insects (EOG6VX118)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB50430   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010268   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14424   Atta cephalotes Leafcutter ant  Acep\ACEP26294   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17910   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13054   Linepithema humile Argentine ant  Lhum\LH13624   Pogonomyrmex barbatus Red harvester ant  Pbar\PB16886   Solenopsis invicta Red fire ant  Sinv\SINV13633   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008346   Pediculus humanus Human body louse  Phum\PHUM570160   Tribolium castaneum Red flour beetle  Tcas\TC000451
Orthologs in non-Insect Arthropods (EOG6G1JXH)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_116424
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (22) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD18973 Drosophila simulans Dsim\GD18974 Drosophila sechellia Dsec\GM24181 Drosophila sechellia Dsec\GM24182 Drosophila erecta Dere\GG16872 Drosophila erecta Dere\GG16873 Drosophila yakuba Dyak\GE24252 Drosophila yakuba Dyak\GE24253 Drosophila ananassae Dana\GF16890 Drosophila ananassae Dana\GF19893 Drosophila pseudoobscura pseudoobscura Dpse\GA17521 Drosophila pseudoobscura pseudoobscura Dpse\GA27076 Drosophila persimilis Dper\GL23845 Drosophila persimilis Dper\GL23846 Drosophila willistoni Dwil\GK11399 Drosophila willistoni Dwil\GK19188 Drosophila virilis Dvir\GJ24251 Drosophila virilis Dvir\GJ24252 Drosophila mojavensis Dmoj\GI22132 Drosophila mojavensis Dmoj\GI22133 Drosophila grimshawi Dgri\GH14225 Drosophila grimshawi Dgri\GH14226
Stocks & Reagents
Stocks Listed in FlyBase ( 22 )
Bloomington	523 jvl1 26094 w1118; Mi{ET1}jvlMB08021
Harvard	- P{XP}jvld00012 - PBac{PB}jvlc03106 - PBac{RB}jvle02766 - PBac{WH}jvlf00590
Kyoto	105962 jvl1
VDRC	v108229 P{KK104198}VIE-260B v26235 w1118; P{GD11011}v26235 v26236 w1118; P{GD11011}v26236 v47836 w1118; P{GD16062}v47836/TM3 v47837 w1118; P{GD16062}v47837/CyO
	More stocks available...
Genomic Clones ( 1 )
	BACR18C01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 105 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD41490 LP10202
Other clones	IP13186 IP21018 MIP14010 MIP14725
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT28182 LD01103 LD01176 LD01194 LD04618 LD04836 LD11017 LD13994 LD15689 LD16046 LD22732 LD30989 LD37695 LD39165 LD40731 LD41214 LD43588 LP02360 RE34510 RE39561 RH01637 RH02952 SD19205 SD23528
Other clones	1323 8223 8268 15382 18596 19237 33503 37956 43638 46981 56929 56991 65840 71902 79582 97103 101099 103537 103839 120609 146815 149446 153986 156970 159503 176433 183844 192304 533624 557868 CK01.9C.D8 CK01.21A.D10 CK01.43C.C6 CK01.44C.F4 CK01.109A.H12 CK01.144A.G12 CK01.167C.H7 DMG4-chr3R.19.001.pred.a EK012048 EK036843 EK037254 EK064301 EK106524 EK106934 EK122658 EK130760 EK155601 EK162830 EK169736 EK175151 EK179903 EK191709 EK193116 EK200259 EK209450 EK219628 EK223857 EK240317 EK249525 EK257432 EK262127 EK262514 EK281337 EK288624 EK292153 EK295129 EN09862 EN12546 EN14203 FGA006D11 FGA007D01 LD07847 LD07893 LD22068 UUGC0936
RNAi & Array Information
Linkouts
Antibody Information
	polyclonal (Dubin-Bar et al., 2011)
Other Information
Discoverer
	Ives, 2nd Dec. 1940.
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG3563 anon-WO0153538.4 anon-WO0153538.5 (FlyBase, 1996-) Source for merge of: CG3563 CG33330 (FlyBase Genome Annotators, 2011) Source for merge of: jvl CG43162 (Dubin-Bar et al., 2011)
Additional comments	Annotations CG3563 and CG33330 merged as CG43162 in release 5.33 of the genome annotation. (FlyBase Genome Annotators, 2011) The 3' exon of release 2 annotation CG3563 (which was deleted in the release 3.1 version of CG3563) has been restored as a distinct annotation, CG33330, in release 3.2 of the genome annotation. (FlyBase Genome Annotators, 2004, FlyBase Genome Annotators, 2004) Source for merge of CG3563 anon-WO0153538.4 anon-WO0153538.5 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Mutants do not exhibit defects in the denticle belt of hairs of the larvae. (Dickinson and Thatcher, 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142132 NM_206488 NM_001104323 NM_001260176 NM_001260177 NM_001260178 NM_001260179 RefSeq (Proteins) • NP_650389 NP_996210 NP_001097793 NP_001247105 NP_001247106 NP_001247107 NP_001247108 DDBJ / EMBL / GenBank • AAF55097 AAK93357 AAS65152 AAS65153 ABW08675 AFH06423 AFH06424 AFH06425 AFH06426 AI515816 AW943566 AX201620 AX201621 AY051933 CZ468430 CZ468431 CZ478966 CZ479046 CZ479047 CZ480537 CZ483049 CZ483050 CZ483173 Entrez Gene - A searchable database of RefSeq genes. • 41788 2768667 UniProtKB/TrEMBL • Q6NNB4 Q7KSJ5 Q7KSJ6 Q9VFG3 Q960P5
Other Crossreferences
Linkouts
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	anon-WO0153538.4   anon-WO0153538.5   CG3563 (Levis et al., 2011.12.16, Khokhar et al., 2008, Baeg et al., 2007, Molnar et al., 2006, Staudt et al., 2005, Keleman et al., 2009.8.5, Kulkarni et al., 2006) CG33330   CG43162 (Dubin-Bar et al., 2011, FlyBase Genome Annotators, 2011, Ni et al., 2010.12.1) jvl (Dubin-Bar et al., 2011, )
Name Synonym	javelin-like (Dubin-Bar et al., 2011) javelinlike
Secondary FlyBase IDs
	FBgn0001293 FBgn0038259 FBgn0045903 FBgn0045914 FBgn0053330 FBgn0260465 FBgn0262718
References ( 37 )
Generate a list of	All references relating to this gene ( 37 )
List References by type	Research paper  ( 12 ) Supplementary material  ( 2 ) Erratum  ( 1 ) Personal communication to FlyBase  ( 14 ) FlyBase analysis  ( 6 ) Book  ( 1 ) Patent  ( 1 )
Recent research papers ( 1 )
	Dubin-Bar et al., 2011, Development 138(21): 4661--4671 Drosophila javelin-like encodes a novel microtubule-associated protein and is required for mRNA localization during oogenesis. [FBrf0216406] Show all research papers ...