Gene Dmel\mwh

FlyGene Wiki Help Close All Open All

General Information

Symbol

Dmel\mwh

Species

D. melanogaster

Name

multiple wing hairs

Annotation symbol

CG43772

Feature type

protein_coding_gene

FlyBase ID

FBgn0264272

Gene Model Status

Current

Stock availability

313 publicly available

Also Known As

CG13913

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

61F4-61F4

Sequence location

3L:1,200,786..1,232,700 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

The gene multiple wing hairs is referred to in FlyBase by the symbol Dmel\mwh (CG43772, FBgn0264272). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: actin binding; Rho GTPase binding. There is experimental evidence that it is involved in the biological process: imaginal disc-derived wing hair site selection; regulation of trichome morphogenesis; negative regulation of actin filament polymerization; imaginal disc-derived wing morphogenesis; imaginal disc-derived wing hair organization. 22 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum; wing cell; actin filament; microchaeta; wing hair; denticle belt. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Armadillo-type fold; Diaphanous FH3; Diaphanous GTPase-binding; GTPase-binding/formin homology 3. Gene sequence location is 3L:1200786..1232700.

User Contributed Data

Beta version, feedback welcome

Phenotypic Description from the Red Book (Lindsley & Zimm 1992)

Gene/Allele symbols may differ from current usage

mwh: multiple wing hairs

mwh: multiple wing hairs
Wing hairs. Left: wild type. Right: mwh. A. Di Pasquale, unpublished.

Affects the trichomes (hairs) of all body regions in the same general way: An increase in the number of elements is correlated with a reduction in length and a disturbance of orientation. Aristae and bracts are included in this pattern; bristles and other sensilla are not. Wing cells contain groups of 2-7 hairs instead of one hair per cell as in wild type; causes supernumerary trichomes over entire integument, but tufts of trichomes only in wing blade (Ouweneel, 1970, Genetica 41: 1-20); may be supernumerary hairs and sensilla on halteres (Ouweneel and van der Meer, 1972, Wilhelm Roux's Arch. Entwicklungsmech. Org. 172: 149-61). Also causes disruption of polarity in legs, wings, and halteres; may disrupt orientation of hairs on leg without affecting their numbers (Bryant and Schneiderman, 1969, Dev. Biol. 20: 263-90); trichomes on wings tend to diverge from vein L3 rather than parallel it as in wild type (Gubb and Garcia-Bellido, 1982, J. Embryol. Exp. Morphol. 68: 37-57). mwh/+ develop mwh phenotype following heat shock at or just prior to the time of cell-hair-extrusion (Mitchell and Petersen, 1984, Genetics 107: s74). Transplants of mutant wing disks to wild-type hosts develop autonomously (Ursprung and Hadorn, 1962, Dev. Biol. 4: 40-60). Widely used as a cell marker in the analysis of cuticular clones. The frequency of mwh spots after somatic recombination in mwh/+ flies increases with increase in the temperature at which the larvae and pupae are raised (Graf, 1986, DIS 63: 65). RK1.

*mwhsemi: multiple wing hairs-semi

Like mwh except that the groups of wing hairs are restricted to wing margins. Cells of wing surface between second and fifth longitudinal veins have single hair with only an occasional group. mwhsemi/mwh is like mwhsemi/mwhsemi. RK1.

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

Update Feed

Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.

FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

61F4-61F4

Limits computationally determined from genome sequence between P{PZ}l(3)05967⁰⁵⁹⁶⁷ and P{PZ}l(3)02640⁰²⁶⁴⁰

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

(Strommen and Falk, 1981, Robertson and Riviera, 1972)

(Strommen and Falk, 1981)

Right of (cM)

(Roberts and Evans-Roberts, 1979, Robertson and Malpica, 1972, Robertson and Riviera, 1972)

Notes

Mapped by difference of T(1;3)sc^J4-mwh and T(1;3)sc^J4-ru distances, using y⁺ as marker.

(Strommen and Falk, 1981)

Gene Model & Products

Please see the GBrowse view of Dmel\mwh for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.44

Gene model reviewed during 5.48

DGC clone SD18376 appears problematic: unspliced intron

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

mwh-RA

FBtr0331392

NM_138238

3554

836

mwh-RB

FBtr0331393

NM_001274314

4063

1068

mwh-RC

FBtr0336737

NM_001274315

4066

1069

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

mwh-PA

FBpp0303809

91.0

836

7.62

NP_612082

AAF47454

mwh-PB

FBpp0303810

116.6

1068

7.31

NP_001261243

AGB93938

mwh-PC

FBpp0307717

116.7

1069

7.31

NP_001261244

AGB93939

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Diaphanous GTPase-binding (IPR010473)

Diaphanous FH3 (IPR010472)

GTPase-binding/formin homology 3 (IPR014768)

Armadillo-type fold (IPR016024)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

dorsal epidermis primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic dorsal epidermis

(Fisher et al., 2012)

embryonic head epidermis

(Fisher et al., 2012)

embryonic ventral epidermis

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

pupal stage P7 -- pharate adult stage P15

wing hair

(Yan et al., 2008)

Comment:from 30 hours APF on

wing | restricted

(Yan et al., 2008)

Comment:from 30 hours APF on

Additional Descriptive Data

mwh protein was observed in wing cells after 30 hours APF. It was observed in an uneven zigzag staining pattern at the cell periphery and accumulates near adherens junctions. It accumulates in both growing and emerging wing hairs and accumulates preferentially in the proximal part of the hair and not in the base at that time. Later in hair morphogenesis (after 36 hr APF), it accumulates preferentially in the base of the hairs.

(Yan et al., 2008)

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		0
central nervous system, pupae P8		3
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		4
head, mated 1-day female		5
head, mated 4-day female		6
head, mated 20-day female		3
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		5
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		1
fat body, larvae L3 wandering		0
fat body, white prepupae		1
fat body, pupae P8		7
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		0
central nervous system, pupae P8		3
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		4
head, mated 1-day female		5
head, mated 4-day female		6
head, mated 20-day female		3
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		5
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		1
fat body, larvae L3 wandering		0
fat body, white prepupae		1
fat body, pupae P8		7
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		0
central nervous system, pupae P8		3
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		4
head, mated 1-day female		5
head, mated 4-day female		6
head, mated 20-day female		3
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		5
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		1
fat body, larvae L3 wandering		0
fat body, white prepupae		1
fat body, pupae P8		7
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		0
central nervous system, pupae P8		3
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		4
head, mated 1-day female		5
head, mated 4-day female		6
head, mated 20-day female		3
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		5
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		1
fat body, larvae L3 wandering		0
fat body, white prepupae		1
fat body, pupae P8		7
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		0
central nervous system, pupae P8		3
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		4
head, mated 1-day female		5
head, mated 4-day female		6
head, mated 20-day female		3
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		5
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		1
fat body, larvae L3 wandering		0
fat body, white prepupae		1
fat body, pupae P8		7
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		0
central nervous system, pupae P8		3
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		4
head, mated 1-day female		5
head, mated 4-day female		6
head, mated 20-day female		3
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		5
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		1
fat body, larvae L3 wandering		0
fat body, white prepupae		1
fat body, pupae P8		7
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		0
central nervous system, pupae P8		3
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		4
head, mated 1-day female		5
head, mated 4-day female		6
head, mated 20-day female		3
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		5
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		1
fat body, larvae L3 wandering		0
fat body, white prepupae		1
fat body, pupae P8		7
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		0
central nervous system, pupae P8		3
head, virgin 1-day female		5
head, virgin 4-day female		6
head, virgin 20-day female		4
head, mated 1-day female		5
head, mated 4-day female		6
head, mated 20-day female		3
head, mated 1-day male		8
head, mated 4-day male		9
head, mated 20-day male		5
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		2
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		1
fat body, larvae L3 wandering		0
fat body, white prepupae		1
fat body, pupae P8		7
carcass, larvae L3 wandering		4
carcass, 1-day adult		1
carcass, 4-day adult		1
carcass, 20-day adult		1
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		3
embryo 08-10hr		4
embryo 10-12hr		11
embryo 12-14hr		21
embryo 14-16hr		21
embryo 16-18hr		5
embryo 18-20hr		4
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		11
larva L3 12hr old		2
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		0
larva L3 puffstage 7-9		1
white prepupae new		1
white prepupae 12hr		3
white prepupae 24hr		5
pupae 2d postWPP		36
pupae 3d postWPP		5
pupae 4d postWPP		2
adult male 01day		3
adult male 05day		2
adult male 30day		3
adult female 01day		1
adult female 05day		0
adult female 30day		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		3
embryo 08-10hr		4
embryo 10-12hr		11
embryo 12-14hr		21
embryo 14-16hr		21
embryo 16-18hr		5
embryo 18-20hr		4
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		11
larva L3 12hr old		2
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		0
larva L3 puffstage 7-9		1
white prepupae new		1
white prepupae 12hr		3
white prepupae 24hr		5
pupae 2d postWPP		(36)
pupae 3d postWPP		5
pupae 4d postWPP		2
adult male 01day		3
adult male 05day		2
adult male 30day		3
adult female 01day		1
adult female 05day		0
adult female 30day		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		3
embryo 08-10hr		4
embryo 10-12hr		11
embryo 12-14hr		21
embryo 14-16hr		21
embryo 16-18hr		5
embryo 18-20hr		4
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		11
larva L3 12hr old		2
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		0
larva L3 puffstage 7-9		1
white prepupae new		1
white prepupae 12hr		3
white prepupae 24hr		5
pupae 2d postWPP		36
pupae 3d postWPP		5
pupae 4d postWPP		2
adult male 01day		3
adult male 05day		2
adult male 30day		3
adult female 01day		1
adult female 05day		0
adult female 30day		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		3
embryo 08-10hr		4
embryo 10-12hr		11
embryo 12-14hr		21
embryo 14-16hr		21
embryo 16-18hr		5
embryo 18-20hr		4
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		11
larva L3 12hr old		2
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		0
larva L3 puffstage 7-9		1
white prepupae new		1
white prepupae 12hr		3
white prepupae 24hr		5
pupae 2d postWPP		36
pupae 3d postWPP		5
pupae 4d postWPP		2
adult male 01day		3
adult male 05day		2
adult male 30day		3
adult female 01day		1
adult female 05day		0
adult female 30day		1
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		3
embryo 08-10hr		4
embryo 10-12hr		11
embryo 12-14hr		21
embryo 14-16hr		21
embryo 16-18hr		5
embryo 18-20hr		4
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		11
larva L3 12hr old		2
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		0
larva L3 puffstage 7-9		1
white prepupae new		1
white prepupae 12hr		3
white prepupae 24hr		5
pupae 2d postWPP		36
pupae 3d postWPP		5
pupae 4d postWPP		2
adult male 01day		3
adult male 05day		2
adult male 30day		3
adult female 01day		1
adult female 05day		0
adult female 30day		1
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		3
embryo 08-10hr		4
embryo 10-12hr		11
embryo 12-14hr		21
embryo 14-16hr		21
embryo 16-18hr		5
embryo 18-20hr		4
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		11
larva L3 12hr old		2
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		0
larva L3 puffstage 7-9		1
white prepupae new		1
white prepupae 12hr		3
white prepupae 24hr		5
pupae 2d postWPP		(36)
pupae 3d postWPP		5
pupae 4d postWPP		2
adult male 01day		3
adult male 05day		2
adult male 30day		3
adult female 01day		1
adult female 05day		0
adult female 30day		1
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		3
embryo 08-10hr		4
embryo 10-12hr		11
embryo 12-14hr		21
embryo 14-16hr		21
embryo 16-18hr		5
embryo 18-20hr		4
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		11
larva L3 12hr old		2
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		0
larva L3 puffstage 7-9		1
white prepupae new		1
white prepupae 12hr		3
white prepupae 24hr		5
pupae 2d postWPP		36
pupae 3d postWPP		5
pupae 4d postWPP		2
adult male 01day		3
adult male 05day		2
adult male 30day		3
adult female 01day		1
adult female 05day		0
adult female 30day		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		3
embryo 08-10hr		4
embryo 10-12hr		11
embryo 12-14hr		21
embryo 14-16hr		21
embryo 16-18hr		5
embryo 18-20hr		4
embryo 20-22hr		1
embryo 22-24hr		1
larva L1		1
larva L2		11
larva L3 12hr old		2
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		0
larva L3 puffstage 7-9		1
white prepupae new		1
white prepupae 12hr		3
white prepupae 24hr		5
pupae 2d postWPP		36
pupae 3d postWPP		5
pupae 4d postWPP		2
adult male 01day		3
adult male 05day		2
adult male 30day		3
adult female 01day		1
adult female 05day		0
adult female 30day		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		1
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		1
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		1
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		1
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		1
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		1
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		1
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		2
embryonic Kc167		0
embryonic S1		0
embryonic S3		1
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		0
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		1
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		1
Ethanol 10% 3 hrs, larvae L3		1
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		2
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		1
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		1
Ethanol 10% 3 hrs, larvae L3		1
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		2
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		1
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		1
Ethanol 10% 3 hrs, larvae L3		1
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		2
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		1
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		1
Ethanol 10% 3 hrs, larvae L3		1
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		2
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		1
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		1
Ethanol 10% 3 hrs, larvae L3		1
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		2
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		1
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		1
Ethanol 10% 3 hrs, larvae L3		1
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		2
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		1
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		1
Ethanol 10% 3 hrs, larvae L3		1
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		2
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		1
cold shock, 4-day adult		1
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		1
Cadmium 100 mM 48 hrs, 4-day adult		1
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		1
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		1
Ethanol 2.5% 3 hrs, larvae L3		1
Ethanol 5% 3 hrs, larvae L3		1
Ethanol 10% 3 hrs, larvae L3		1
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		1
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		2
Paraquat 10 mM 48 hrs, 4-day adult		2
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

PC00264

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

mwh¹

viable, with Scer\GAL4^pnr-MD237

mwh^GD8165

Other Phenotypes

Allele

body color defective, with Scer\GAL4^pnr-MD237

mwh^GD8165

planar polarity defective

planar polarity defective, with Scer\GAL4^ptc-559.1, Scer\GAL4^tub.PU

mwh^Scer\UAS.cYa

planar polarity defective | cell autonomous | somatic clone

mwh¹

planar polarity defective | heat sensitive

mwh⁶

visible

mwh¹

visible, with Scer\GAL4^ap-md544

mwh^GD8165

visible, with Scer\GAL4^pnr-MD237

mwh^GD8165

visible, with Scer\GAL4^ptc-559.1

mwh^GD8165

visible, with Scer\GAL4^ptc-559.1, Scer\GAL4^tub.PU

mwh^Scer\UAS.cYa

visible | adult stage | recessive | somatic clone

mwh^unspecified

visible | heat sensitive

visible | heat sensitive (with mwh¹)

mwh⁶

visible | heat sensitive (with mwh⁶)

mwh¹

visible | recessive

Phenotype manifest in

Allele

actin filament

mwh¹

denticle belt

mwh¹

mesothoracic tergum, with Scer\GAL4^pnr-MD237

mwh^GD8165

microchaeta

mwh¹

microchaeta & wing

mwh¹

trichogen cell, with Scer\GAL4^pnr-MD237

mwh^GD8165

trichome & adult head | dorsal | somatic clone

mwh^unspecified

wing | pupal stage

mwh¹

wing cell

mwh¹

wing hair

wing hair, with Scer\GAL4^ptc-559.1, Scer\GAL4^tub.PU

mwh^Scer\UAS.cYa

wing hair | cell autonomous | somatic clone

mwh¹

wing hair | cell autonomous | somatic clone | supernumerary

mwh^unspecified

wing hair | heat sensitive

mwh⁶

wing hair | supernumerary

wing hair | supernumerary, with Scer\GAL4^ap-md544

mwh^GD8165

wing hair | supernumerary, with Scer\GAL4^en-e16E

mwh^GD8165

wing hair | supernumerary, with Scer\GAL4^ptc-559.1

mwh^GD8165

wing hair | supernumerary, with Scer\GAL4^ptc-559.1, Scer\GAL4^tub.PU

mwh^Scer\UAS.cYa

wing hair | supernumerary | heat sensitive

mwh⁶

wing hair | supernumerary | heat sensitive (with mwh¹)

mwh⁶

wing hair | supernumerary | heat sensitive (with mwh⁶)

mwh¹

Classical Alleles ( 13 )

For All Classical Alleles Show

Allele of mwh	Class	Mutagen	Stocks	Known lesion
mwh¹	amorphic allele - genetic evidence, loss of function allele	spontaneous	305	Yes
mwh²	loss of function allele		1	Yes
mwh^MB09358			1	--
mwh^MI00737			1	--
mwh^MI06967			1	--
mwh⁺			0	--
mwh³	loss of function allele		0	Yes
mwh⁴	loss of function allele		0	Yes
mwh⁵	loss of function allele		0	Yes
mwh⁶	heat sensitive hypomorphic allele - genetic evidence		0	Yes
mwh^RdeMed			0	--
mwh^semi		spontaneous	0	--
mwh^unspecified			0	--

Alleles Carried on Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Allele of mwh	Mutagen	Stocks	Known lesion
mwh^GD8165	in vitro construct - RNAi in vitro construct - regulatory fusion	3	Yes
mwh^+t38	in vitro construct - genomic fragment	1	Yes
mwh^HMS00180	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
mwh^{Act5C.T:Avic\GFP-EGFP}	FLPase	0	Yes
mwh^C.Scer\UAS	in vitro construct - regulatory fusion	0	Yes
mwh^{GBD.FH3.Scer\UAS.T:Ivir\HA1}	in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
mwh^NIG.13913R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
mwh^{Scer\FRT.Act5C.T:Avic\GFP-EGFP}	in vitro construct - regulatory fusion	0	Yes
mwh^Scer\UAS.cYa	in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Duplicated in

Dp(1;YS)sc^V1mwh⁺

Dp(3;Y;1)M1

(Garcia-Bellido and Ripoll, 1973)

Dp(3;Y;1)M2

(Garcia-Bellido and Ripoll, 1973)

Dp(3;Y;1)M3

(Garcia-Bellido and Ripoll, 1973)

T(Y;3)P6

Ts(Y;3Lt)P5

(Lewis, 1969)

Ts(YSt;3Lt)D8

(Smith et al., 1985)

Not duplicated in

Dp(3;4)h⁺44

(Ingham et al., 1985)

Ts(Y;3Lt)P3

(Lewis, 1969)

Not disrupted in

Df(3L)h-i22

(Ingham et al., 1985)

Tp(3;3)h^M3

(Ingham et al., 1985)

Disrupted in

In(3L)mwh¹

(Strutt and Warrington, 2008)

Partially disrupted in

In(3L)mwh¹

(Strutt and Warrington, 2008)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{NIG.13913R}

P{TRiP.HMS00180}

P{UAS-mwh.C}

P{UAS-mwh.HA.GBD.FH3}

P{UAS-mwh.Y}

characterization construct

P{Act5C(FRT.polyA)EGFP-mwh}

P{Act5C(-FRT)EGFP-mwh}

P{mwh.+t38}

P{UAS-in::mwh.L}

PBac{mwh.+t38}

Insertions

Type of insertions

Name

Expression data

insertion of enhancer trap binary system

Mi{ET1}mwh^MB09358

miscellaneous insertions

Mi{MIC}mwh^MI00737

Mi{MIC}mwh^MI06967

Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )

There is no information supporting a cellular component term for this gene.

(Based on a review of available data on: 2006-05-23)

Terms Based on Experimental Evidence ( 5 terms )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

imaginal disc-derived wing hair organization