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Gene Dmel\CG43780

General Information
Symbol	Dmel\CG43780	Species	D. melanogaster
Name		Annotation symbol	CG43780
Feature type	protein_coding_gene	FlyBase ID	FBgn0264302
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	CG8600
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	65F5-65F5	Sequence location	3L:7,326,644..7,328,326 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG43780 (FBgn0264302). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is 3L:7326644..7328326.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 65F5-65F5
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG43780 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 gene_with_dicistronic_mRNA ; SO:0000722
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG43780-RA FBtr0331507  NM_139848   1430   162 CG43780-RB FBtr0331508  NM_001169898   1415   157
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG43780-PA   FBpp0303897   19.2   162   7.23     NP_648105   AAF50580 CG43780-PB   FBpp0303898   18.6   157   7.20     NP_001163369   ACZ94640
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA438855   AA439788   AA802010   AA803180   AA950904   AE014296 AAF50580   AE014296 ACZ94640   AI258323   AI260227   AI295721   AI456423   AY060444   BI168240   BI168509   BI171045   BI212612   BI214621   BI229234   BI232794   BI236840   BI241153   BI243006   BI243049   BI363686   BI364701   BI365989   BI366715   BI366857   BI374668   BI375169   BI483500   BI484374   BI484527   BI484709   BI486644   BI570004   BI570128   BI578970   BI614512   BI623100   BP547719   BP549061   BP549603   BP550291   BP554723   BP559472   CK659865   CO281147   CO293090   CO300725   CO302362   CO304384   CO307650   CO311805   CO315726   CO316458   CO316780   CO322729   CZ473009   CZ473010   EC065945   EC066510   EC074570   EC076095   EC077869   EC194790   EC204014   EC205926   EC213740   EC213858   EC215050   EC222059   EC224183   EC234424   EC237220   EC238066   EV575351
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	E1JIE5 Q9VS49
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   dorsal epidermis primordium   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) salivary gland body primordium   (Fisher et al., 2012) tracheal primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   atrium   (Fisher et al., 2012) embryonic dorsal epidermis   (Fisher et al., 2012) embryonic epipharynx   (Fisher et al., 2012) embryonic esophagus   (Fisher et al., 2012) embryonic head epidermis   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic hypopharynx   (Fisher et al., 2012) embryonic large intestine   (Fisher et al., 2012) embryonic optic lobe   (Fisher et al., 2012) embryonic/larval salivary gland   (Fisher et al., 2012) embryonic/larval visceral branch   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    24 central nervous system, pupae P8    28 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    12 head, mated 1-day female    10 head, mated 4-day female    10 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    17 head, mated 20-day male    15 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    4 digestive system, 4-day adult    6 digestive system, 20-day adult    5 fat body, larvae L3 wandering    5 fat body, white prepupae    14 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    57 ovary, mated 4-day female    50 testis, mated 4-day male    10 accessory gland, mated 4-day male    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (82) central nervous system, larvae L3    24 central nervous system, pupae P8  (28) head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    12 head, mated 1-day female    10 head, mated 4-day female    10 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    17 head, mated 20-day male    15 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    4 digestive system, 4-day adult    6 digestive system, 20-day adult    5 fat body, larvae L3 wandering    5 fat body, white prepupae    14 fat body, pupae P8  (32) carcass, larvae L3 wandering  (49) carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female  (57) ovary, mated 4-day female  (50) testis, mated 4-day male    10 accessory gland, mated 4-day male    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    24 central nervous system, pupae P8    28 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    12 head, mated 1-day female    10 head, mated 4-day female    10 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    17 head, mated 20-day male    15 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    4 digestive system, 4-day adult    6 digestive system, 20-day adult    5 fat body, larvae L3 wandering    5 fat body, white prepupae    14 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    57 ovary, mated 4-day female    50 testis, mated 4-day male    10 accessory gland, mated 4-day male    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    24 central nervous system, pupae P8    28 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    12 head, mated 1-day female    10 head, mated 4-day female    10 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    17 head, mated 20-day male    15 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    4 digestive system, 4-day adult    6 digestive system, 20-day adult    5 fat body, larvae L3 wandering    5 fat body, white prepupae    14 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    57 ovary, mated 4-day female    50 testis, mated 4-day male    10 accessory gland, mated 4-day male    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    24 central nervous system, pupae P8    28 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    12 head, mated 1-day female    10 head, mated 4-day female    10 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    17 head, mated 20-day male    15 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    4 digestive system, 4-day adult    6 digestive system, 20-day adult    5 fat body, larvae L3 wandering    5 fat body, white prepupae    14 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    57 ovary, mated 4-day female    50 testis, mated 4-day male    10 accessory gland, mated 4-day male    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (82) central nervous system, larvae L3    24 central nervous system, pupae P8  28 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    12 head, mated 1-day female    10 head, mated 4-day female    10 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    17 head, mated 20-day male    15 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    4 digestive system, 4-day adult    6 digestive system, 20-day adult    5 fat body, larvae L3 wandering    5 fat body, white prepupae    14 fat body, pupae P8  32 carcass, larvae L3 wandering  (49) carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female  (57) ovary, mated 4-day female  (50) testis, mated 4-day male    10 accessory gland, mated 4-day male    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    24 central nervous system, pupae P8    28 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    12 head, mated 1-day female    10 head, mated 4-day female    10 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    17 head, mated 20-day male    15 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    4 digestive system, 4-day adult    6 digestive system, 20-day adult    5 fat body, larvae L3 wandering    5 fat body, white prepupae    14 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    57 ovary, mated 4-day female    50 testis, mated 4-day male    10 accessory gland, mated 4-day male    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    82 central nervous system, larvae L3    24 central nervous system, pupae P8    28 head, virgin 1-day female    9 head, virgin 4-day female    9 head, virgin 20-day female    12 head, mated 1-day female    10 head, mated 4-day female    10 head, mated 20-day female    10 head, mated 1-day male    11 head, mated 4-day male    17 head, mated 20-day male    15 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    13 digestive system, larvae L3 wandering    10 digestive system, 1-day adult    4 digestive system, 4-day adult    6 digestive system, 20-day adult    5 fat body, larvae L3 wandering    5 fat body, white prepupae    14 fat body, pupae P8    32 carcass, larvae L3 wandering    49 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    8 ovary, virgin 4-day female    57 ovary, mated 4-day female    50 testis, mated 4-day male    10 accessory gland, mated 4-day male    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    85 embryo 02-04hr    117 embryo 04-06hr    111 embryo 06-08hr    236 embryo 08-10hr    324 embryo 10-12hr    319 embryo 12-14hr    334 embryo 14-16hr    227 embryo 16-18hr    148 embryo 18-20hr    110 embryo 20-22hr    68 embryo 22-24hr    71 larva L1    60 larva L2    37 larva L3 12hr old    24 larva L3 puffstage 1-2    39 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    90 white prepupae new    92 white prepupae 12hr    87 white prepupae 24hr    147 pupae 2d postWPP    105 pupae 3d postWPP    99 pupae 4d postWPP    23 adult male 01day    19 adult male 05day    17 adult male 30day    22 adult female 01day    43 adult female 05day    59 adult female 30day    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (85) embryo 02-04hr  (117) embryo 04-06hr  (111) embryo 06-08hr  (236) embryo 08-10hr  (324) embryo 10-12hr  (319) embryo 12-14hr  (334) embryo 14-16hr  (227) embryo 16-18hr  (148) embryo 18-20hr  (110) embryo 20-22hr  (68) embryo 22-24hr  (71) larva L1  (60) larva L2  (37) larva L3 12hr old    24 larva L3 puffstage 1-2  (39) larva L3 puffstage 3-6  (62) larva L3 puffstage 7-9  (90) white prepupae new  (92) white prepupae 12hr  (87) white prepupae 24hr  (147) pupae 2d postWPP  (105) pupae 3d postWPP  (99) pupae 4d postWPP    23 adult male 01day    19 adult male 05day    17 adult male 30day    22 adult female 01day  (43) adult female 05day  (59) adult female 30day  (57) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    85 embryo 02-04hr  (117) embryo 04-06hr  (111) embryo 06-08hr  (236) embryo 08-10hr  (324) embryo 10-12hr  (319) embryo 12-14hr  (334) embryo 14-16hr  (227) embryo 16-18hr  (148) embryo 18-20hr  (110) embryo 20-22hr    68 embryo 22-24hr    71 larva L1    60 larva L2    37 larva L3 12hr old    24 larva L3 puffstage 1-2    39 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    90 white prepupae new    92 white prepupae 12hr    87 white prepupae 24hr  (147) pupae 2d postWPP  105 pupae 3d postWPP    99 pupae 4d postWPP    23 adult male 01day    19 adult male 05day    17 adult male 30day    22 adult female 01day    43 adult female 05day    59 adult female 30day    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    85 embryo 02-04hr    117 embryo 04-06hr    111 embryo 06-08hr    236 embryo 08-10hr    324 embryo 10-12hr    319 embryo 12-14hr    334 embryo 14-16hr    227 embryo 16-18hr    148 embryo 18-20hr    110 embryo 20-22hr    68 embryo 22-24hr    71 larva L1    60 larva L2    37 larva L3 12hr old    24 larva L3 puffstage 1-2    39 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    90 white prepupae new    92 white prepupae 12hr    87 white prepupae 24hr    147 pupae 2d postWPP    105 pupae 3d postWPP    99 pupae 4d postWPP    23 adult male 01day    19 adult male 05day    17 adult male 30day    22 adult female 01day    43 adult female 05day    59 adult female 30day    57 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    85 embryo 02-04hr    117 embryo 04-06hr    111 embryo 06-08hr    236 embryo 08-10hr    324 embryo 10-12hr    319 embryo 12-14hr    334 embryo 14-16hr    227 embryo 16-18hr    148 embryo 18-20hr    110 embryo 20-22hr    68 embryo 22-24hr    71 larva L1    60 larva L2    37 larva L3 12hr old    24 larva L3 puffstage 1-2    39 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    90 white prepupae new    92 white prepupae 12hr    87 white prepupae 24hr    147 pupae 2d postWPP    105 pupae 3d postWPP    99 pupae 4d postWPP    23 adult male 01day    19 adult male 05day    17 adult male 30day    22 adult female 01day    43 adult female 05day    59 adult female 30day    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (85) embryo 02-04hr  (117) embryo 04-06hr  (111) embryo 06-08hr  (236) embryo 08-10hr  (324) embryo 10-12hr  (319) embryo 12-14hr  (334) embryo 14-16hr  (227) embryo 16-18hr  (148) embryo 18-20hr  (110) embryo 20-22hr  (68) embryo 22-24hr  (71) larva L1  (60) larva L2  (37) larva L3 12hr old    24 larva L3 puffstage 1-2  (39) larva L3 puffstage 3-6  (62) larva L3 puffstage 7-9  (90) white prepupae new  (92) white prepupae 12hr  (87) white prepupae 24hr  (147) pupae 2d postWPP  (105) pupae 3d postWPP  (99) pupae 4d postWPP    23 adult male 01day    19 adult male 05day    17 adult male 30day    22 adult female 01day  (43) adult female 05day  (59) adult female 30day  (57) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    85 embryo 02-04hr  117 embryo 04-06hr  111 embryo 06-08hr  (236) embryo 08-10hr  (324) embryo 10-12hr  (319) embryo 12-14hr  (334) embryo 14-16hr  (227) embryo 16-18hr  (148) embryo 18-20hr  110 embryo 20-22hr    68 embryo 22-24hr    71 larva L1    60 larva L2    37 larva L3 12hr old    24 larva L3 puffstage 1-2    39 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    90 white prepupae new    92 white prepupae 12hr    87 white prepupae 24hr  (147) pupae 2d postWPP  105 pupae 3d postWPP    99 pupae 4d postWPP    23 adult male 01day    19 adult male 05day    17 adult male 30day    22 adult female 01day    43 adult female 05day    59 adult female 30day    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    85 embryo 02-04hr    117 embryo 04-06hr    111 embryo 06-08hr    236 embryo 08-10hr    324 embryo 10-12hr    319 embryo 12-14hr    334 embryo 14-16hr    227 embryo 16-18hr    148 embryo 18-20hr    110 embryo 20-22hr    68 embryo 22-24hr    71 larva L1    60 larva L2    37 larva L3 12hr old    24 larva L3 puffstage 1-2    39 larva L3 puffstage 3-6    62 larva L3 puffstage 7-9    90 white prepupae new    92 white prepupae 12hr    87 white prepupae 24hr    147 pupae 2d postWPP    105 pupae 3d postWPP    99 pupae 4d postWPP    23 adult male 01day    19 adult male 05day    17 adult male 30day    22 adult female 01day    43 adult female 05day    59 adult female 30day    57 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    9 Schneider line 2 Sg4    12 embryonic 1182-4H    24 embryonic GM2    14 embryonic Kc167    11 embryonic S1    50 embryonic S3    8 leg disc CME L1    13 wing disc CME-W2    35 wing disc ML-DmD8    29 wing disc ML-DmD9    17 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    20 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    18 CNS ML-DmBG1-c1    61 CNS ML-DmBG2-c2    88 tumorous blood cells mbn2    14 ovary fGS/OSS    11 ovary OSC    19 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    9 Schneider line 2 Sg4    12 embryonic 1182-4H    24 embryonic GM2    14 embryonic Kc167    11 embryonic S1  (50) embryonic S3    8 leg disc CME L1    13 wing disc CME-W2  (35) wing disc ML-DmD8  (29) wing disc ML-DmD9    17 wing disc ML-DmD16-c3  (32) wing disc ML-DmD21    20 wing disc ML-DmD32  (50) haltere disc ML-DmD17-c3  (34) eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5  (30) mixed discs ML-DmD4-c1    18 CNS ML-DmBG1-c1  (61) CNS ML-DmBG2-c2  (88) tumorous blood cells mbn2    14 ovary fGS/OSS    11 ovary OSC    19 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    9 Schneider line 2 Sg4    12 embryonic 1182-4H    24 embryonic GM2    14 embryonic Kc167    11 embryonic S1    50 embryonic S3    8 leg disc CME L1    13 wing disc CME-W2    35 wing disc ML-DmD8    29 wing disc ML-DmD9    17 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    20 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    18 CNS ML-DmBG1-c1    61 CNS ML-DmBG2-c2    88 tumorous blood cells mbn2    14 ovary fGS/OSS    11 ovary OSC    19 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    9 Schneider line 2 Sg4    12 embryonic 1182-4H    24 embryonic GM2    14 embryonic Kc167    11 embryonic S1    50 embryonic S3    8 leg disc CME L1    13 wing disc CME-W2    35 wing disc ML-DmD8    29 wing disc ML-DmD9    17 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    20 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    18 CNS ML-DmBG1-c1    61 CNS ML-DmBG2-c2    88 tumorous blood cells mbn2    14 ovary fGS/OSS    11 ovary OSC    19 ovary OSS    23 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    9 Schneider line 2 Sg4    12 embryonic 1182-4H    24 embryonic GM2    14 embryonic Kc167    11 embryonic S1    50 embryonic S3    8 leg disc CME L1    13 wing disc CME-W2    35 wing disc ML-DmD8    29 wing disc ML-DmD9    17 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    20 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    18 CNS ML-DmBG1-c1    61 CNS ML-DmBG2-c2    88 tumorous blood cells mbn2    14 ovary fGS/OSS    11 ovary OSC    19 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    9 Schneider line 2 Sg4    12 embryonic 1182-4H    24 embryonic GM2    14 embryonic Kc167    11 embryonic S1  (50) embryonic S3    8 leg disc CME L1    13 wing disc CME-W2  (35) wing disc ML-DmD8  29 wing disc ML-DmD9    17 wing disc ML-DmD16-c3  32 wing disc ML-DmD21    20 wing disc ML-DmD32  (50) haltere disc ML-DmD17-c3  (34) eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5  30 mixed discs ML-DmD4-c1    18 CNS ML-DmBG1-c1  (61) CNS ML-DmBG2-c2  (88) tumorous blood cells mbn2    14 ovary fGS/OSS    11 ovary OSC    19 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    9 Schneider line 2 Sg4    12 embryonic 1182-4H    24 embryonic GM2    14 embryonic Kc167    11 embryonic S1    50 embryonic S3    8 leg disc CME L1    13 wing disc CME-W2    35 wing disc ML-DmD8    29 wing disc ML-DmD9    17 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    20 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    18 CNS ML-DmBG1-c1    61 CNS ML-DmBG2-c2    88 tumorous blood cells mbn2    14 ovary fGS/OSS    11 ovary OSC    19 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    9 Schneider line 2 Sg4    12 embryonic 1182-4H    24 embryonic GM2    14 embryonic Kc167    11 embryonic S1    50 embryonic S3    8 leg disc CME L1    13 wing disc CME-W2    35 wing disc ML-DmD8    29 wing disc ML-DmD9    17 wing disc ML-DmD16-c3    32 wing disc ML-DmD21    20 wing disc ML-DmD32    50 haltere disc ML-DmD17-c3    34 eye-antennal disc ML-DmD11    25 antennal disc ML-DmD20-c5    30 mixed discs ML-DmD4-c1    18 CNS ML-DmBG1-c1    61 CNS ML-DmBG2-c2    88 tumorous blood cells mbn2    14 ovary fGS/OSS    11 ovary OSC    19 ovary OSS    23 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    9 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    39 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    9 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3  (33) Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult  (30) Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3  (28) Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (39) Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult  (30) Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    9 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    39 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    9 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    39 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    9 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    39 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    9 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3  (33) Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult  30 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3  28 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (39) Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult  30 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    9 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    39 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    13 cold shock, 4-day adult    9 heat shock, 4-day adult    22 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    18 Cadmium 100 mM 48 hrs, 4-day adult    30 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    19 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    17 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    16 Ethanol 10% 3 hrs, larvae L3    15 Caffeine 1.5 mg/ml 4 hrs, larvae L3    18 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    39 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    17 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (Graveley et al., 2011) mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LD47606
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG43780d02813 Sterility Allele fertile CG43780d02813 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG43780 Class Mutagen Stocks Known lesion CG43780d02813 P-element activity 2 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG43780 Class Mutagen Stocks Known lesion CG43780GD3859 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG43780KK107175 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG43780NIG.8600R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{NIG.8600R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{XP}CG43780d02813 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene_with_dicistronic_mRNA (FlyBase Genome Annotators, 2012) gene_with_stop_codon_read_through (FlyBase Genome Annotators, 2008) protein_coding_gene (FlyBase Genome Annotators, 2012)
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG43780 allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (27) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6T78PV Dipteran inclusive ortholog search EOG6T1HWW Insect inclusive ortholog search EOG6K6F1X Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6T78PV)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG43780     Drosophila simulans   Dsim\GD13072     Drosophila sechellia   Dsec\GM13774     Drosophila erecta   Dere\GG14978     Drosophila yakuba   Dyak\GE20425     Drosophila ananassae   Dana\GF23858     Drosophila pseudoobscura pseudoobscura   Dpse\GA21196     Drosophila persimilis   Dper\GL21151     Drosophila willistoni   Dwil\GK16670     Drosophila virilis   Dvir\GJ12251     Drosophila mojavensis   Dmoj\GI12358     Drosophila grimshawi   Dgri\GH16095
Orthologs in non-Drosophila Dipterans (EOG6T1HWW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000281   Anopheles gambiae Malaria mosquito  Agam\AGAP005675   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006935
Orthologs in non-Dipteran Insects (EOG6K6F1X)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB46502   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG014946   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15317   Atta cephalotes Leafcutter ant  Acep\ACEP16572   Camponotus floridanus Florida carpenter ant  Cflo\CFLO21000   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL12702   Linepithema humile Argentine ant  Lhum\LH21663   Pogonomyrmex barbatus Red harvester ant  Pbar\PB25708   Acyrthosiphon pisum Pea aphid  Apim\ACYPI34441   Bombyx mori Silkmoth  Bmor\BGIBMGA000616   Pediculus humanus Human body louse  Phum\PHUM537360   Tribolium castaneum Red flour beetle  Tcas\TC006991
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	19182 w1118; P{XP}CG43780d02813
Harvard	- P{XP}CG43780d02813
VDRC	v100677 P{KK107175}VIE-260B v49931 w1118; P{GD3859}v49931/CyO
Genomic Clones ( 2 )
	BACR09E21 BACR11B04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 72 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD47606
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM03718 GM10353 LD13223 LD14450 LD31067 LD36441 LP01480 LP03944 LP09434 LP17969 RE08836 RE09266 RE12710 RE17729 RE20587 RE26972 RE28924 RE32961 RE38170 RE40530 RE40587 RE48605 RE49868 RE51405 RE52311 RE52483 RE62317 RE62917 RE66407 RE67464 RE67642 RE67851 RE70095 RE72927 RH02231 RH02383 RH43889 RH55182
Other clones	37921 54364 63112 72793 99690 103608 105206 107496 146022 149038 159367 161327 161478 CK01.6B.F8 CK01.21A.G2 Dmel_dig_013997_0602_2455 EK156050 EK179259 EK184007 EK188741 EK201663 EK226563 EK244546 EK255152 EK262322 EK265018 EK265839 FGH120A03 FGM003D09 FGM102D06 FGM206C12 FGM231D06 FGM321B07
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	Annotation CG8600 split into CG43780 and CG43781 in release 5.45 of the genome annotation. Split based on RNA-seq junction and RNA-seq expression data supporting a dicistronic model and conservation of CG43781 translation start in Drosophila species. (FlyBase Genome Annotators, 2012) One or more of the processed transcripts for this gene contain(s) two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG43780 and CG43781. (FlyBase Genome Annotators, 2012)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_139848 NM_001169898 RefSeq (Proteins) • NP_648105 NP_001163369 DDBJ / EMBL / GenBank • AAF50580 ACZ94640 CZ473009 CZ473010 Entrez Gene - A searchable database of RefSeq genes. • 38810 UniProtKB/TrEMBL • E1JIE5 Q9VS49
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD47606
Linkouts
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG8600 (Jungreis, 2011.11.18, Telonis-Scott et al., 2009, Giot et al., 2003, FlyBase Genome Annotators, 2008) CG43780 (FlyBase Genome Annotators, 2012, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
	FBgn0035765
References ( 18 )
Research paper	Telonis-Scott et al., 2009, J. Insect Physiol. 55(6): 549--555 Selection for cold resistance alters gene transcript levels in Drosophila melanogaster. [FBrf0208060]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Horn et al., 2011.11.16, GenomeRNAi reagent in FlyBase GenomeRNAi reagent in FlyBase [FBrf0216883] Jungreis, 2011.11.18, Stop codon readthrough: excluded candidates. Stop codon readthrough: excluded candidates. [FBrf0216885] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] M. Booker, 2008.6.2, full complement of DRSC amplicons full complement of DRSC amplicons [FBrf0206127] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Genome Annotators, 2012, Changes affecting gene model number or type in release 5.45 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.45 of the annotated D.melanogaster genome. [FBrf0217539] FlyBase Genome Annotators, 2008, Changes affecting gene model number or type in release 5.11 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.11 of the annotated D.melanogaster genome. [FBrf0205039] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]