hib, l(3)88Aa, SPOP, l(3)2004, l(3)03477
a member of a conserved family of proteins that serve as substrate adaptors for Cullin3-mediated ubiquitylation - regulates Cubitus interruptus levels by targeting it for degradation
Please see the JBrowse view of Dmel\rdx for information on other features
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5' UTR contains an ORF described as a putative conserved uORF (FBrf0204849); potential peptide 25aa in length.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
A non-AUG start codon may be used for translation of one or more transcripts of this gene; based on the presence of conserved protein signatures within the 5' UTR without an in-frame AUG (FBrf0243886).
Interacts with ci and gft/CUL3.
The MATH domain interacts with ci.
The BTB (POZ) domain interacts with gft/CUL3.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\rdx using the Feature Mapper tool.
Comment: maternally deposited
Comment: anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as ventral nerve cord anlage
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
rdx is expressed posterior to the morphogenetic furrow in the eye disc. Expression is elevated near the anterior-posterior compartment boundary of antenna, leg and wing discs.
GBrowse - Visual display of RNA-Seq signals
View Dmel\rdx in GBrowse 23-54
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: rdx CG9924
Source for merge of: rdx mei-P19
Source for merge of: l(3)dsl6 l(3)SG40
Source for merge of: l(3)88Aa l(3)03477
Source for merge of: CG12537 anon-WO0118547.577
Source for merge of: rdx CG9924
Source for merge of: CG9924 BEST:GM07940
Source for merge of: rdx l(3)S086909
Source for merge of CG12537 anon-WO0118547.577 was sequence comparison ( date:051113 ).
Host gene for maternally inherited stable intronic sequence RNA (sisRNA).
Area matching Drosophila EST AA696584 (inverted).
Identification: In a genetic screen for meiotic mutants.
One allele generates embryos with mitotic defects that often fail to completely cellularize, hence, the name "roadkill".