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Gene Dmel\gpp

General Information
Symbol	Dmel\gpp	Species	D. melanogaster
Name	grappa	Annotation symbol	CG42803
Feature type	protein_coding_gene	FlyBase ID	FBgn0264495
Gene Model Status	Current	Stock availability	32 publicly available
Also Known As	CG10272, l(3)03342
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	83E6-83E7	Sequence location	3R:2,232,577..2,274,917 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene grappa is referred to in FlyBase by the symbol Dmel\gpp (CG42803, FBgn0264495). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: histone methyltransferase activity (H3-K79 specific). There is experimental evidence that it is involved in the biological process: positive regulation of gene silencing by miRNA; lateral inhibition. 47 alleles are reported. The phenotypes of these alleles are annotated with: eye; sex comb; arista; ommatidium. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Histone H3-K79 methyltransferase; Histone H3-K79 methyltransferase, metazoa; Histone methylation DOT1. Gene sequence location is 3R:2232577..2274917.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 83E6-83E7   Limits computationally determined from genome sequence between P{lacW}casj1C2 and P{PZ}lab01241
Experimentally Determined Cytological Location
Cytogenetic map Notes References 83E-83E   (determined by in situ hybridisation)   (Shanower et al., 2005) 83F1-83F2   (determined by in situ hybridisation)   (Spradling et al., 1999) 83F1-83F2   (determined by in situ hybridisation)   (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\gpp for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) gpp-RB FBtr0303787  NM_169143   7305   1848 gpp-RC FBtr0303788  NM_169142   7691   1848 gpp-RD FBtr0303789  NM_169144   8391   2137 gpp-RE FBtr0303790  NM_141398   10117   1848 gpp-RF FBtr0334322  NM_001275387   8396   1898
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein gpp-PB   FBpp0292799   201.3   1848   9.86     NP_731084   AAN13379 gpp-PC   FBpp0292800   201.3   1848   9.86     NP_731083   AAN13378 gpp-PD   FBpp0292801   231.6   2137   9.55     NP_731085   AAN13380 gpp-PE   FBpp0292802   201.3   1848   9.86     NP_649655   AAF54122 gpp-PF   FBpp0306435   206.5   1898   9.66     NP_001262316   AGB95699
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Histone H3-K79 methyltransferase (IPR025789) Histone H3-K79 methyltransferase, metazoa (IPR021169) Histone methylation DOT1 (IPR013110)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201589   AA202529   AA699133   AA735819   AA820945   AE014297 AAF54122   AE014297 AAN13378   AE014297 AAN13379   AE014297 AAN13380   AE014297 AGB95699   AI520494   AI533426   AI533427   AI945519   AI946523   AW944404   AX094195   AY060467 AAL25506   BE975750   BE975751   BF487201   BF488175   BF489073   BF491969   BF503983   BG632181   BG635160   BG638429   BI237662   BI352329   BI568833   BI569027   BI569359   BI569425   BI570752   BI571559   BI573530   BI573871   BI581107   BI591414   BI616456   BI626750   BI628253   BT011458   BT025080   BT099926   CK605079   CL706559   CO153659   CO154302   CO265483   CO266508   CO267219   CO268773   CO274824   CO274878   CO280537   CO300726   CO309036   CO309899   CO320617   CO322064   CO326562   CO328048   CO333685   CO339023   EC061443   EC067974   EC074948   EC082518   EC085536   EC198883   EC210323   EC213333   EC226673   EC227678   EC234425   EC243334   EC246351   EC254874   EC266452   EL874689   EL874816   EL875055   ES690642   ES690650   ES690654   ES690660   ES690674   ES690675   ES690684   ES690686   ES690757   ES690761   ES690770   ES690777   ES690780   ES690786   ES690796   EV584849   G01163   GH751306   GH759009   GH760004   GH760745   GH805717   GH807106   GH813198   GH814931   GH817652   GH827653   GH828182   GH865012   GH867383   GH872960   GH875673   GH885818   GH887065   GH893196   GH896423   GH913306   GH918222   GH918327   GH929077   GR705763
UniProtKB/Swiss-Prot	Q8INR6
UniProtKB/TrEMBL	Q7KSW9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    38 central nervous system, pupae P8    27 head, virgin 1-day female    15 head, virgin 4-day female    14 head, virgin 20-day female    11 head, mated 1-day female    16 head, mated 4-day female    13 head, mated 20-day female    11 head, mated 1-day male    23 head, mated 4-day male    19 head, mated 20-day male    19 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    7 fat body, white prepupae    23 fat body, pupae P8    16 carcass, larvae L3 wandering    29 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    62 ovary, mated 4-day female    83 testis, mated 4-day male    39 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (46) central nervous system, larvae L3  (38) central nervous system, pupae P8  (27) head, virgin 1-day female    15 head, virgin 4-day female    14 head, virgin 20-day female    11 head, mated 1-day female    16 head, mated 4-day female    13 head, mated 20-day female    11 head, mated 1-day male    23 head, mated 4-day male    19 head, mated 20-day male    19 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    7 fat body, white prepupae    23 fat body, pupae P8    16 carcass, larvae L3 wandering  (29) carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female  (62) ovary, mated 4-day female  (83) testis, mated 4-day male  (39) accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    38 central nervous system, pupae P8    27 head, virgin 1-day female    15 head, virgin 4-day female    14 head, virgin 20-day female    11 head, mated 1-day female    16 head, mated 4-day female    13 head, mated 20-day female    11 head, mated 1-day male    23 head, mated 4-day male    19 head, mated 20-day male    19 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    7 fat body, white prepupae    23 fat body, pupae P8    16 carcass, larvae L3 wandering    29 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    62 ovary, mated 4-day female    83 testis, mated 4-day male    39 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    38 central nervous system, pupae P8    27 head, virgin 1-day female    15 head, virgin 4-day female    14 head, virgin 20-day female    11 head, mated 1-day female    16 head, mated 4-day female    13 head, mated 20-day female    11 head, mated 1-day male    23 head, mated 4-day male    19 head, mated 20-day male    19 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    7 fat body, white prepupae    23 fat body, pupae P8    16 carcass, larvae L3 wandering    29 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    62 ovary, mated 4-day female    83 testis, mated 4-day male    39 accessory gland, mated 4-day male    9 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    38 central nervous system, pupae P8    27 head, virgin 1-day female    15 head, virgin 4-day female    14 head, virgin 20-day female    11 head, mated 1-day female    16 head, mated 4-day female    13 head, mated 20-day female    11 head, mated 1-day male    23 head, mated 4-day male    19 head, mated 20-day male    19 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    7 fat body, white prepupae    23 fat body, pupae P8    16 carcass, larvae L3 wandering    29 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    62 ovary, mated 4-day female    83 testis, mated 4-day male    39 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (46) central nervous system, larvae L3  (38) central nervous system, pupae P8  27 head, virgin 1-day female    15 head, virgin 4-day female    14 head, virgin 20-day female    11 head, mated 1-day female    16 head, mated 4-day female    13 head, mated 20-day female    11 head, mated 1-day male    23 head, mated 4-day male    19 head, mated 20-day male    19 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    7 fat body, white prepupae    23 fat body, pupae P8    16 carcass, larvae L3 wandering  29 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female  (62) ovary, mated 4-day female  (83) testis, mated 4-day male  (39) accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    38 central nervous system, pupae P8    27 head, virgin 1-day female    15 head, virgin 4-day female    14 head, virgin 20-day female    11 head, mated 1-day female    16 head, mated 4-day female    13 head, mated 20-day female    11 head, mated 1-day male    23 head, mated 4-day male    19 head, mated 20-day male    19 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    7 fat body, white prepupae    23 fat body, pupae P8    16 carcass, larvae L3 wandering    29 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    62 ovary, mated 4-day female    83 testis, mated 4-day male    39 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    46 central nervous system, larvae L3    38 central nervous system, pupae P8    27 head, virgin 1-day female    15 head, virgin 4-day female    14 head, virgin 20-day female    11 head, mated 1-day female    16 head, mated 4-day female    13 head, mated 20-day female    11 head, mated 1-day male    23 head, mated 4-day male    19 head, mated 20-day male    19 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    4 digestive system, 4-day adult    9 digestive system, 20-day adult    7 fat body, larvae L3 wandering    7 fat body, white prepupae    23 fat body, pupae P8    16 carcass, larvae L3 wandering    29 carcass, 1-day adult    10 carcass, 4-day adult    11 carcass, 20-day adult    9 ovary, virgin 4-day female    62 ovary, mated 4-day female    83 testis, mated 4-day male    39 accessory gland, mated 4-day male    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    29 embryo 04-06hr    25 embryo 06-08hr    29 embryo 08-10hr    35 embryo 10-12hr    23 embryo 12-14hr    32 embryo 14-16hr    33 embryo 16-18hr    24 embryo 18-20hr    19 embryo 20-22hr    22 embryo 22-24hr    22 larva L1    8 larva L2    5 larva L3 12hr old    4 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    14 white prepupae new    13 white prepupae 12hr    15 white prepupae 24hr    22 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    15 adult male 05day    21 adult male 30day    23 adult female 01day    20 adult female 05day    27 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (36) embryo 02-04hr  (29) embryo 04-06hr    25 embryo 06-08hr  (29) embryo 08-10hr  (35) embryo 10-12hr    23 embryo 12-14hr  (32) embryo 14-16hr  (33) embryo 16-18hr    24 embryo 18-20hr    19 embryo 20-22hr    22 embryo 22-24hr    22 larva L1    8 larva L2    5 larva L3 12hr old    4 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    14 white prepupae new    13 white prepupae 12hr    15 white prepupae 24hr    22 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    15 adult male 05day    21 adult male 30day    23 adult female 01day    20 adult female 05day  (27) adult female 30day  (27) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    29 embryo 04-06hr    25 embryo 06-08hr    29 embryo 08-10hr    35 embryo 10-12hr    23 embryo 12-14hr    32 embryo 14-16hr    33 embryo 16-18hr    24 embryo 18-20hr    19 embryo 20-22hr    22 embryo 22-24hr    22 larva L1    8 larva L2    5 larva L3 12hr old    4 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    14 white prepupae new    13 white prepupae 12hr    15 white prepupae 24hr    22 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    15 adult male 05day    21 adult male 30day    23 adult female 01day    20 adult female 05day    27 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    29 embryo 04-06hr    25 embryo 06-08hr    29 embryo 08-10hr    35 embryo 10-12hr    23 embryo 12-14hr    32 embryo 14-16hr    33 embryo 16-18hr    24 embryo 18-20hr    19 embryo 20-22hr    22 embryo 22-24hr    22 larva L1    8 larva L2    5 larva L3 12hr old    4 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    14 white prepupae new    13 white prepupae 12hr    15 white prepupae 24hr    22 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    15 adult male 05day    21 adult male 30day    23 adult female 01day    20 adult female 05day    27 adult female 30day    27 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    29 embryo 04-06hr    25 embryo 06-08hr    29 embryo 08-10hr    35 embryo 10-12hr    23 embryo 12-14hr    32 embryo 14-16hr    33 embryo 16-18hr    24 embryo 18-20hr    19 embryo 20-22hr    22 embryo 22-24hr    22 larva L1    8 larva L2    5 larva L3 12hr old    4 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    14 white prepupae new    13 white prepupae 12hr    15 white prepupae 24hr    22 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    15 adult male 05day    21 adult male 30day    23 adult female 01day    20 adult female 05day    27 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (36) embryo 02-04hr  29 embryo 04-06hr    25 embryo 06-08hr  29 embryo 08-10hr  (35) embryo 10-12hr    23 embryo 12-14hr  32 embryo 14-16hr  (33) embryo 16-18hr    24 embryo 18-20hr    19 embryo 20-22hr    22 embryo 22-24hr    22 larva L1    8 larva L2    5 larva L3 12hr old    4 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    14 white prepupae new    13 white prepupae 12hr    15 white prepupae 24hr    22 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    15 adult male 05day    21 adult male 30day    23 adult female 01day    20 adult female 05day  27 adult female 30day  27 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    29 embryo 04-06hr    25 embryo 06-08hr    29 embryo 08-10hr    35 embryo 10-12hr    23 embryo 12-14hr    32 embryo 14-16hr    33 embryo 16-18hr    24 embryo 18-20hr    19 embryo 20-22hr    22 embryo 22-24hr    22 larva L1    8 larva L2    5 larva L3 12hr old    4 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    14 white prepupae new    13 white prepupae 12hr    15 white prepupae 24hr    22 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    15 adult male 05day    21 adult male 30day    23 adult female 01day    20 adult female 05day    27 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    36 embryo 02-04hr    29 embryo 04-06hr    25 embryo 06-08hr    29 embryo 08-10hr    35 embryo 10-12hr    23 embryo 12-14hr    32 embryo 14-16hr    33 embryo 16-18hr    24 embryo 18-20hr    19 embryo 20-22hr    22 embryo 22-24hr    22 larva L1    8 larva L2    5 larva L3 12hr old    4 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    12 larva L3 puffstage 7-9    14 white prepupae new    13 white prepupae 12hr    15 white prepupae 24hr    22 pupae 2d postWPP    20 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    15 adult male 05day    21 adult male 30day    23 adult female 01day    20 adult female 05day    27 adult female 30day    27 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    5 embryonic 1182-4H    25 embryonic GM2    14 embryonic Kc167    13 embryonic S1    20 embryonic S3    11 leg disc CME L1    8 wing disc CME-W2    8 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    3 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    19 ovary fGS/OSS    34 ovary OSC    27 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    5 embryonic 1182-4H    25 embryonic GM2    14 embryonic Kc167    13 embryonic S1    20 embryonic S3    11 leg disc CME L1    8 wing disc CME-W2    8 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    3 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    19 ovary fGS/OSS  (34) ovary OSC  (27) ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    5 embryonic 1182-4H    25 embryonic GM2    14 embryonic Kc167    13 embryonic S1    20 embryonic S3    11 leg disc CME L1    8 wing disc CME-W2    8 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    3 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    19 ovary fGS/OSS    34 ovary OSC    27 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    5 embryonic 1182-4H    25 embryonic GM2    14 embryonic Kc167    13 embryonic S1    20 embryonic S3    11 leg disc CME L1    8 wing disc CME-W2    8 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    3 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    19 ovary fGS/OSS    34 ovary OSC    27 ovary OSS    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    5 embryonic 1182-4H    25 embryonic GM2    14 embryonic Kc167    13 embryonic S1    20 embryonic S3    11 leg disc CME L1    8 wing disc CME-W2    8 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    3 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    19 ovary fGS/OSS    34 ovary OSC    27 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    5 embryonic 1182-4H    25 embryonic GM2    14 embryonic Kc167    13 embryonic S1    20 embryonic S3    11 leg disc CME L1    8 wing disc CME-W2    8 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    3 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    19 ovary fGS/OSS  (34) ovary OSC  27 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    5 embryonic 1182-4H    25 embryonic GM2    14 embryonic Kc167    13 embryonic S1    20 embryonic S3    11 leg disc CME L1    8 wing disc CME-W2    8 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    3 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    19 ovary fGS/OSS    34 ovary OSC    27 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    5 embryonic 1182-4H    25 embryonic GM2    14 embryonic Kc167    13 embryonic S1    20 embryonic S3    11 leg disc CME L1    8 wing disc CME-W2    8 wing disc ML-DmD8    19 wing disc ML-DmD9    16 wing disc ML-DmD16-c3    20 wing disc ML-DmD21    3 wing disc ML-DmD32    13 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    14 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    15 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    19 ovary fGS/OSS    34 ovary OSC    27 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    28 cold shock, 4-day adult    23 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    66 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    26 Ethanol 2.5% 3 hrs, larvae L3    47 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    57 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    43 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (28) cold shock, 4-day adult    23 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult  (66) Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult  (48) Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult  26 Ethanol 2.5% 3 hrs, larvae L3  (47) Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (57) Caffeine 25 mg/ml 48 hrs, 4-day adult  (30) Paraquat 5 mM 48 hrs, 4-day adult  (42) Paraquat 10 mM 48 hrs, 4-day adult  (43) Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    28 cold shock, 4-day adult    23 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    66 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    26 Ethanol 2.5% 3 hrs, larvae L3    47 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    57 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    43 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    28 cold shock, 4-day adult    23 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    66 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    26 Ethanol 2.5% 3 hrs, larvae L3    47 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    57 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    43 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    28 cold shock, 4-day adult    23 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    66 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    26 Ethanol 2.5% 3 hrs, larvae L3    47 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    57 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    43 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  28 cold shock, 4-day adult    23 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult  (66) Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult  (48) Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult  26 Ethanol 2.5% 3 hrs, larvae L3  (47) Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (57) Caffeine 25 mg/ml 48 hrs, 4-day adult  30 Paraquat 5 mM 48 hrs, 4-day adult  (42) Paraquat 10 mM 48 hrs, 4-day adult  (43) Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    28 cold shock, 4-day adult    23 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    66 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    26 Ethanol 2.5% 3 hrs, larvae L3    47 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    57 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    43 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    28 cold shock, 4-day adult    23 heat shock, 4-day adult    20 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    24 Cadmium 100 mM 48 hrs, 4-day adult    66 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    7 Zinc 4.5 mM 48 hrs, 4-day adult    26 Ethanol 2.5% 3 hrs, larvae L3    47 Ethanol 5% 3 hrs, larvae L3    2 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    57 Caffeine 25 mg/ml 48 hrs, 4-day adult    30 Paraquat 5 mM 48 hrs, 4-day adult    42 Paraquat 10 mM 48 hrs, 4-day adult    43 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (Graveley et al., 2011) mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal gppCB03567 lethal (with Df(3R)WIN11) gpp8 gpp61A gppIN1 gppX gppXXV lethal (with gpp8) gppIN1 gppX gppXXV lethal (with gpp61A) gpp03342 gppIN1 gppX gppXXV lethal (with gpp03342) gpp61A gppIN1 gppX lethal (with gppIN1) gpp8 gpp61A gpp03342 gppX gppXXV lethal (with gppX) gpp8 gpp61A gpp03342 gppIN1 gppXXV lethal (with gppXXV) gpp8 gpp61A gppIN1 gppX lethal | embryonic stage | recessive gpp8 lethal | larval stage, with Scer\GAL4Act5C.PU gppGD6924 lethal | larval stage | recessive gppX lethal | pharate adult stage (with gpp8) gpp61A lethal | pharate adult stage (with gpp61A) gpp8 lethal | pharate adult stage | recessive gppIN1 lethal | pupal stage, with Scer\GAL4Act5C.PU gppGD16506 lethal | pupal stage, with Scer\GAL4pnr-MD237 gppGD6924 lethal | recessive gpp61A gpp03342 gpp09312 gppQ210X gppsA3484 partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 gppGD16061 partially lethal - majority die | recessive gppS073214b viable gpp1A gpp72A gpp94A Other Phenotypes Allele developmental rate defective | larval stage gppX enhancer of variegation, with P{hsp26-pt-T}39C-72 gpp8 locomotor behavior defective, with Scer\GAL4hs.PB gppGS13895 gppGS17621 non-enhancer of variegation, with P{hsp26-pt-T}39C-4 gpp1A gpp8 gpp61A gpp72A gpp94A gppXXV non-enhancer of variegation, with P{hsp26-pt-T}39C-5 gpp1A gpp72A gpp94A non-enhancer of variegation, with P{hsp26-pt-T}39C-27 gpp1A gpp72A gpp94A non-enhancer of variegation, with P{hsp26-pt-T}39C-31 gpp1A non-enhancer of variegation, with P{hsp26-pt-T}39C-50 gpp1A non-enhancer of variegation, with P{hsp26-pt-T}39C-55 gpp1A non-enhancer of variegation, with P{hsp26-pt-T}39C-62 gpp1A non-enhancer of variegation, with P{hsp26-pt-T}39C-72 gpp1A non-enhancer of variegation, with P{hsp26-pt-T}118E-10 gpp1A gpp61A gpp72A gpp94A gppXXV non-enhancer of variegation, with P{hsp26-pt-T}118E-12 gpp1A gpp8 gpp61A gpp72A gpp94A gppXXV non-enhancer of variegation, with P{hsp26-pt-T}Dyrk3118E-15 gpp1A gpp8 non-suppressor of variegation, with P{hsp26-pt-T}39C-4 gpp1A gpp8 gpp61A gpp72A gpp94A gppXXV non-suppressor of variegation, with P{hsp26-pt-T}39C-5 gpp1A gpp72A gpp94A non-suppressor of variegation, with P{hsp26-pt-T}39C-27 gpp1A gpp72A gpp94A non-suppressor of variegation, with P{hsp26-pt-T}39C-31 gpp1A non-suppressor of variegation, with P{hsp26-pt-T}39C-50 gpp1A non-suppressor of variegation, with P{hsp26-pt-T}39C-55 gpp1A non-suppressor of variegation, with P{hsp26-pt-T}39C-62 gpp1A non-suppressor of variegation, with P{hsp26-pt-T}39C-72 gpp1A non-suppressor of variegation, with P{hsp26-pt-T}118E-10 gpp1A gpp61A gpp72A gpp94A gppXXV non-suppressor of variegation, with P{hsp26-pt-T}118E-12 gpp1A gpp8 gpp61A gpp72A gpp94A gppXXV non-suppressor of variegation, with P{hsp26-pt-T}Dyrk3118E-15 gpp1A gpp8 short lived gpp1A short lived | heat sensitive, with Scer\GAL4hs.PB gppGS13895 gppGS17621 stress response defective | adult stage gpp1A stress response defective | adult stage, with Scer\GAL4hs.PB gppGS13895 gppGS17621 suppressor of variegation, with P{hsp26-pt-T}39C-27 gpp61A gppXXV suppressor of variegation, with P{hsp26-pt-T}39C-31 gpp61A gpp72A gpp94A gppXXV suppressor of variegation, with P{hsp26-pt-T}39C-50 gpp8 gpp61A gppX gppXXV suppressor of variegation, with P{hsp26-pt-T}39C-55 gpp61A gpp72A gpp94A gppX gppXXV suppressor of variegation, with P{hsp26-pt-T}39C-62 gpp61A gpp72A gpp94A gppXXV suppressor of variegation, with P{hsp26-pt-T}39C-72 gpp61A gpp72A gppX gppXXV suppressor of variegation, with P{hsp26-pt-T}Dyrk3118E-15 gpp61A gpp72A gppX gppXXV suppressor of variegation | partially, with P{hsp26-pt-T}39C-5 gpp8 gpp61A gppX gppXXV suppressor of variegation | partially, with P{hsp26-pt-T}39C-31 gpp8 suppressor of variegation | partially, with P{hsp26-pt-T}39C-50 gpp72A gpp94A suppressor of variegation | partially, with P{hsp26-pt-T}39C-62 gpp8 suppressor of variegation | partially, with P{hsp26-pt-T}39C-72 gpp94A suppressor of variegation | partially, with P{hsp26-pt-T}118E-10 gpp8 suppressor of variegation | partially, with P{hsp26-pt-T}Dyrk3118E-15 gpp94A visible gpp72A gpp94A gppunspecified visible, with Scer\GAL4pnr-MD237 gppGD16061 visible (with gpp8) gpp61A visible (with gpp61A) gpp8 visible | dominant gpp61A visible | male gpp1A Phenotype manifest in Allele abdominal sternite 6 | male gpp94A gpp72A gpp1A abdominal tergite 4 | ectopic | male gpp61A abdominal tergite 5 | male gpp61A abdominal tergite 5 | male (with gpp8) gpp61A abdominal tergite 5 | male (with gpp61A) gpp8 abdominal tergite 7 | ectopic | male gpp1A adult abdominal segment 4 | ectopic | male gpp94A gppIN1 gpp72A gpp1A adult abdominal segment 5 | male gpp94A gppIN1 gpp72A gpp1A adult abdominal segment 6 | male gpp94A gppIN1 gpp72A gpp1A arista (with gpp8) gpp61A arista (with gpp61A) gpp8 chaeta | supernumerary, with Scer\GAL4pnr-MD237 gppGD16061 eye gppunspecified leg | ectopic (with gpp8) gpp61A leg | ectopic (with gpp61A) gpp8 ommatidium gppunspecified prothoracic tarsal segment 4 | male (with gpp61A) gppX prothoracic tarsal segment 4 | male (with gppX) gpp61A sex comb gppIN1 sex comb (with gpp8) gpp61A sex comb (with gpp61A) gpp8 gppX sex comb (with gppX) gpp61A sex comb | ectopic (with gpp61A) gppX sex comb | ectopic (with gppX) gpp61A sternite | male (with gpp8) gpp61A sternite | male (with gpp61A) gpp8 tergite | male gpp94A gpp72A gpp1A
Classical Alleles ( 37 )
For All Classical Alleles Show
Allele of gpp Class Mutagen Stocks Known lesion gppNP5372 2 -- gpp03342 P-element activity 1 Yes gpp61A ethyl methanesulfonate 1 -- gppBG00006 1 -- gppc03951 1 -- gppCB-0347-3 1 -- gppd03021 1 -- gppe00213 1 -- gppe00987 1 -- gppe01765 1 -- gppe02709 1 -- gppe04070 1 -- gppf03758 1 -- gppf04922 1 -- gppf06155 1 -- gppf07224 1 -- gppGS13895 1 Yes gppMI00944 1 -- gppMI02698 1 -- gppNP7436 1 -- gppXXV X ray 1 Yes gpp09312 P-element activity 0 -- gpp1A ethyl methanesulfonate 0 -- gpp72A ethyl methanesulfonate 0 -- gpp8 ethyl methanesulfonate 0 -- gpp94A ethyl methanesulfonate 0 -- gppCB03567 P-element activity 0 Yes gppDG10802 0 -- gppEY02591 P-element activity 0 -- gppf06793 0 -- gppGS17621 0 Yes gppIN1 Delta2-3 0 Yes gppQ210X ethyl methanesulfonate 0 Yes gppS073214b Delta2-3 0 -- gppsA3484 P-element activity 0 -- gppunspecified 0 -- gppX X ray 0 Yes
Alleles Carried on Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Allele of gpp Class Mutagen Stocks Known lesion gppGD16061 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes gppGD16506 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes gppGD6924 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes gppGL01325 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes gppHMJ02129 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes gppHMS00160 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes gppHMS02612 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes gppJF01283 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes gppJF01284 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes gppKK107875 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Not disrupted in	Df(3R)Scr (BDGP Project Members, 1994-1999, Spradling et al., 1999) Df(3R)Tpl10 (BDGP Project Members, 1994-1999)
Disrupted in	Df(3R)BSC193 (Gresens and Cook, 2006.8.29) Df(3R)BSC738 (Christensen et al., 2009.2.28) Df(3R)Dfd13 (Shanower et al., 2005, Spradling et al., 1999) Df(3R)WIN11 (Shanower et al., 2005) In(3R)gppX (Shanower et al., 2005) In(3R)gppXXV (Shanower et al., 2005)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6924} NA P{GD16506} NA P{KK107875} NA P{TRiP.GL01325} NA P{TRiP.HMJ02129} NA P{TRiP.HMS00160} NA P{TRiP.HMS02612} NA P{TRiP.JF01283} NA P{TRiP.JF01284} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}gppIN1 No P{lacW}gppS073214b No P{lacW}gppsA3484 No P{PZ}gpp03342 No P{PZ}gpp09312 No insertion of mobile activating element P{EPgy2}gppEY02591 NA P{GSV6}gppGS13895 NA P{GSV6}gppGS17621 NA P{XP}gppd03021 NA miscellaneous insertions Mi{MIC}gppMI00944 NA Mi{MIC}gppMI02698 NA P{GT1}gppBG00006 NA P{PTT-GB}gppCB03567 NA P{RS3}gppCB-0347-3 NA P{wHy}gppDG10802 NA PBac{PB}gppc03951 NA PBac{RB}gppe00213 NA PBac{RB}gppe00987 NA PBac{RB}gppe01765 NA PBac{RB}gppe02709 NA PBac{RB}gppe04070 NA PBac{WH}gppf03758 NA PBac{WH}gppf04922 NA PBac{WH}gppf06155 NA PBac{WH}gppf06793 NA PBac{WH}gppf07224 NA insertion of enhancer trap binary system P{GawB}gppNP5372 No P{GawB}gppNP7436 No
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function
CV term Evidence References
histone methyltransferase activity (H3-K79 specific) inferred from mutant phenotype (Shanower et al., 2005)
Biological Process
CV term Evidence References
lateral inhibition inferred from mutant phenotype (Mummery-Widmer et al., 2009) positive regulation of gene silencing by miRNA inferred from mutant phenotype (Pressman et al., 2012)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
nucleus inferred from electronic annotation with InterPro:IPR021169 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions gpp allele Gene References gpp1A Abd-B (Shanower et al., 2005) Pc (Shanower et al., 2005) Pcl (Shanower et al., 2005) Sce (Shanower et al., 2005) Scm (Shanower et al., 2005) gpp8 hh (Shanower et al., 2005) Pc (Shanower et al., 2005) Pcl (Shanower et al., 2005) Sce (Shanower et al., 2005) Scm (Shanower et al., 2005) gpp61A Abd-B (Shanower et al., 2005) Snr1 (Marenda et al., 2004) gpp94A Pc (Shanower et al., 2005) Pcl (Shanower et al., 2005) Sce (Shanower et al., 2005) Snr1 (Marenda et al., 2004) gppX Pc (Shanower et al., 2005) Pcl (Shanower et al., 2005) Sce (Shanower et al., 2005) Scm (Shanower et al., 2005) gppXXV Pc (Shanower et al., 2005) Pcl (Shanower et al., 2005) Sce (Shanower et al., 2005) Scm (Shanower et al., 2005) Snr1 (Marenda et al., 2004) unspecified iab-7PRE (Shanower et al., 2005) MCP-PRE (Shanower et al., 2005) UbxPRE (Shanower et al., 2005)
External Data
Linkouts
Orthologs
OrthoDB Orthologs (45) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6PVPJ0 Dipteran inclusive ortholog search EOG6T1HVG Insect inclusive ortholog search EOG6NVXF6 Arthropod inclusive ortholog search EOG612JM9 Metazoa inclusive ortholog search EOG64V21H
Orthologs in Drosophila Species (EOG6PVPJ0)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\gpp     Drosophila simulans   Dsim\GD19874 Y   Drosophila sechellia   Dsec\GM10895 Y   Drosophila erecta   Dere\GG13435 Y   Drosophila yakuba   Dyak\GE10220 Y   Drosophila ananassae   Dana\GF18361 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10209 Y   Drosophila persimilis   Dper\GL21749 Y   Drosophila willistoni   Dwil\GK13498 Y   Drosophila virilis   Dvir\GJ24607 Y   Drosophila mojavensis   Dmoj\GI23014 Y   Drosophila grimshawi   Dgri\GH19535 Y
Orthologs in non-Drosophila Dipterans (EOG6T1HVG)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL006783   Anopheles gambiae Malaria mosquito  Agam\AGAP003282   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ001411
Orthologs in non-Dipteran Insects (EOG6NVXF6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB46691   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003026   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13801   Atta cephalotes Leafcutter ant  Acep\ACEP19233   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14371   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL16530   Linepithema humile Argentine ant  Lhum\LH12573   Pogonomyrmex barbatus Red harvester ant  Pbar\PB12155   Solenopsis invicta Red fire ant  Sinv\SINV26371   Solenopsis invicta Red fire ant  Sinv\SINV26373   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009680   Bombyx mori Silkmoth  Bmor\BGIBMGA002656   Pediculus humanus Human body louse  Phum\PHUM478060   Tribolium castaneum Red flour beetle  Tcas\TC013593
Orthologs in non-Insect Arthropods (EOG612JM9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_47843   Daphnia pulex Water flea  Dpux\JGI_V11_198981   Ixodes scapularis Deer tick  Isca\ISCW021226
Orthologs in non-Arthropod Metazoa (EOG64V21H)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\F54F7.7   Caenorhabditis elegans Nematode  Cele\W06D11.4   Caenorhabditis elegans Nematode  Cele\Y39G10AR.18   Caenorhabditis elegans Nematode  Cele\ZC53.6   Caenorhabditis elegans Nematode  Cele\F55G7.2   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005570gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_024691gn   Danio rerio Zebrafish  Drer\dot1l   Xenopus tropicalis Western clawed frog  Xtro\dot1l   Gallus gallus Domestic chicken  Ggal\DOT1L   Mus musculus House mouse  Mmus\Dot1l   Rattus norvegicus Norway rat  Rnor\Dot1l   Homo sapiens Human  Hsap\ENSG00000104885
Human Orthologs (1)
Gene OMIM HGNC Hsap\ENSG00000104885
AAA Orthologs (20) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD19874 Drosophila simulans Dsim\GD19875 Drosophila sechellia Dsec\GM10895 Drosophila sechellia Dsec\GM10896 Drosophila erecta Dere\GG13435 Drosophila erecta Dere\GG13446 Drosophila yakuba Dyak\GE10220 Drosophila yakuba Dyak\GE10221 Drosophila ananassae Dana\GF18361 Drosophila ananassae Dana\GF18363 Drosophila pseudoobscura pseudoobscura Dpse\GA10209 Drosophila persimilis Dper\GL21749 Drosophila willistoni Dwil\GK13498 Drosophila willistoni Dwil\GK18956 Drosophila virilis Dvir\GJ24607 Drosophila virilis Dvir\GJ24608 Drosophila mojavensis Dmoj\GI23013 Drosophila mojavensis Dmoj\GI23014 Drosophila grimshawi Dgri\GH19535 Drosophila grimshawi Dgri\GH19536
Stocks & Reagents
Stocks Listed in FlyBase ( 32 )
Harvard	- P{XP}gppd03021 - PBac{PB}gppc03951 - PBac{RB}gppe00213 - PBac{RB}gppe00987 - PBac{RB}gppe01765 - PBac{RB}gppe02709 - PBac{RB}gppe04070 - PBac{WH}gppf03758 - PBac{WH}gppf04922 - PBac{WH}gppf06155 - PBac{WH}gppf07224
VDRC	v16001 w1118 P{GD6924}v16001
	More stocks available...
Genomic Clones ( 1 )
	BACR32D05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 97 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP15004 RE33929 SD05230
Other clones	IP21657
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT05238 AT21919 AT23375 AT24772 AT28828 GH04796 GM09917 GM18821 HL07769 LD02189 LD04653 LD40672 RH01107 RH01129 RH01246 RH01449 RH01492 RH05184 RH05529 RH06810 RH09137 RH09353 RH46412 RH56609 RH67801 SD05231 UT01660
Other clones	AT31653 bs13g07 bs27d06 bs44e10 Dmel_dig_018157_0608_2550 EK092640 EK115605 EK115830 EK142760 EK146634 EK149133 EK154307 EK179263 EK187133 EK219722 EK259948 EK286539 EK307664 EN02530 EN03861 EP00635 EP04215 EP08501 IP14804 IP14904 IP15104 LD24893 MB6-CG10272.a RC0-DA0001-120700-011-H11 RC0-DA0001-120700-013-D02 RC0-DA0001-120700-013-G04 RC0-DA0001-120700-015-D05 RC0-DA0001-120700-017-F08 RC0-DA0001-120700-017-G05 RC0-DA0001-120700-019-E01 RC0-DA0001-120700-019-G05 RC0-DA0001-130700-114-G08 RC0-DA0001-130700-115-G12 RC0-DA0001-130700-118-B05 RC0-DA0001-130700-119-E02 RC0-DA0001-130700-120-A08 RC0-DA0001-130700-120-G02 RC0-DA0001-130700-121-H03 RP003011557 RP003024090 RP003122410 RP003133553 RP003152661 RP003188709 RP003196511 RP003210556 RP003228905 RP003267631 RP003271276 RP003296232 RP003308405 RP003320039 RP003331638 RP003337608 RP003338487 RP003356946 RP003440990 RP003496382 RP003514574 RP003615838 RP003657955
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
Etymology
	The gene is named "grappa" because of the light yellow phenotype associated with the posterior-to-anterior transformation of the A5 and A6 male tergite plates seen in mutants (this light colour reminded one of the authors of a favourite drink from his not so distant youth and thus is the origin of the name). (Shanower et al., 2005)
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG10272 BcDNA:SD05230 (FlyBase, 1996-) Source for merge of: gpp anon-WO0118547.319 (FlyBase, 1996-) Source for merge of: gpp CG10272 l(3)03342 (Shanower et al., 2005) Source for merge of: gpp CG33324 (FlyBase Genome Annotators, 2010) Source for merge of: gpp l(3)S073214b (Link et al., 2007)
Additional comments	Annotations CG10272 and CG33324 merged as CG42803 in release 5.30 of the genome annotation. (FlyBase Genome Annotators, 2010) The 3' exon of release 2 annotation CG10272 (which was deleted in the release 3.1 version of CG10272) has been restored as a distinct annotation, CG33324, in release 3.2 of the genome annotation. (FlyBase Genome Annotators, 2004, FlyBase Genome Annotators, 2004) Source for merge of gpp anon-WO0118547.319 was sequence comparison (date:051113). (FlyBase, 1996-) Source for merge of CG10272 BcDNA:SD05230 was a shared cDNA (date:030728). (FlyBase, 1996-)
Other Comments
	gpp mutants exhibit phenotypes and genetic interactions that are characteristic of both Polycomb-Group and trithorax-Group genes. (Shanower et al., 2005) Area matching Drosophila EST AA735819. (Davies, 2001.3.15) A novel trithorax group gene, identified in a genetic screen devised for the isolation of dominant suppressors of pairing-sensitive miniwhite inactivation. (Muller et al., 1994)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_141398 NM_169142 NM_169143 NM_169144 NM_001275387 RefSeq (Proteins) • NP_649655 NP_731083 NP_731084 NP_731085 NP_001262316 DDBJ / EMBL / GenBank • AA202529 AA735819 AAF54122 AAL25506 AAN13378 AAN13379 AAN13380 AAS65121 AGB95699 AI533426 AI945519 AI946523 AW944404 AX094195 AY060467 BI237662 CL706559 G01163 Entrez Gene - A searchable database of RefSeq genes. • 40793 2768660 UniProtKB/Swiss-Prot • Q8INR6 UniProtKB/TrEMBL • Q7KSW9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Histone H3-K79 methyltransferase (IPR025789) Histone H3-K79 methyltransferase, metazoa (IPR021169) Histone methylation DOT1 (IPR013110)
Linkouts
Synonyms & Secondary IDs ( 17 )
Reported As
Symbol Synonym	0732/14 (Deak et al., 1997) anon-WO0118547.319   BcDNA:SD05230   CG10272 (Keleman et al., 2009.8.5, Dlakic, 2001, Shanower et al., 2005, FlyBase, 1996-, Buszczak et al., 2007, Quinones-Coello, 2007, Deloger et al., 2009, Oliver, 2001.8.16, Ni et al., 2008) CG33324   CG42803 (Ni et al., 2011.7.19, FlyBase Genome Annotators, 2010, Ni et al., 2010.12.1) dDot1 (Mohan et al., 2010) dDOT1L (Feng et al., 2002) gpp (Link et al., 2007, Gresens and Cook, 2006.8.29, Vazquez et al., 2006, Quinones-Coello, 2007, Doheny et al., 2008, Christensen et al., 2009.2.28, List et al., 2009, Mohan et al., 2010, Zhou et al., 2008) Gpp (Hochwagen, 2006, Deloger et al., 2009) grp   l(3)03342 (Spradling et al., 1999, BDGP Project Members, 1994-1999, ) l(3)S073214b   l(3)sA3484
Name Synonym	grappa (Shanower, 2006.12.12, Doheny et al., 2008, List et al., 2009, Mohan et al., 2010, Link et al., 2007) Grappa (Pressman et al., 2012) lethal (3) S073214b
Secondary FlyBase IDs
	FBgn0010795 FBgn0011041 FBgn0014963 FBgn0037444 FBgn0046759 FBgn0053324 FBgn0060693 FBgn0062097 FBgn0261972
References ( 53 )
Generate a list of	All references relating to this gene ( 53 )
List References by type	Research paper  ( 16 ) Supplementary material  ( 5 ) Review  ( 2 ) Personal communication to FlyBase  ( 17 ) Abstract  ( 5 ) FlyBase analysis  ( 6 ) Patent  ( 1 ) DNA/RNA sequence record  ( 1 )
Recent research papers ( 1 )
	Pressman et al., 2012, G3 (Bethesda) 2(4): 437--448 A Systematic Genetic Screen to Dissect the MicroRNA Pathway in Drosophila. [FBrf0218180] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...