ang, CG 8487, sec7-family GEF
Gene model reviewed during 5.49
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\garz using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\garz in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
garz is not involved in invagination or in the elongation of salivary gland cells, but is involved in apical membrane expansion.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Identification: in a screen for genes which when overexpressed cause motorneuron pathfinding and or synaptogenesis errors.
Involved in endocytosis/membrane trafficking.
Mittler and Goldberg, 16th Sep. 1948.
The gene is named "angina" based on the narrow tracheal lumen phenotype seen in mutant embryos.