• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\RapGAP1

General Information
Symbol	Dmel\RapGAP1	Species	D. melanogaster
Name	Rap GTPase activating protein 1	Annotation symbol	CG44086
Feature type	protein_coding_gene	FlyBase ID	FBgn0264895
Gene Model Status	Current	Stock availability	30 publicly available
Also Known As	Rapgap1, CG13791, CG13790, CG34374, CG33529
Genomic Location
Chromosome (arm)	2L	Recombination map	2-
Cytogenetic map	28A4-28B2	Sequence location	2L:7,497,805..7,578,680 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Rap GTPase activating protein 1 is referred to in FlyBase by the symbol Dmel\RapGAP1 (CG44086, FBgn0264895). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: Rap GTPase activator activity. There is experimental evidence that it is involved in the biological process: inter-male aggressive behavior; activation of Rap GTPase activity. 42 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum; pigment cell. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: GoLoco motif; Rap GTPase activating proteins domain. Gene sequence location is 2L:7497805..7578680.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03	Alleles RapGAP1[MI07759]
FB2013_02	Controlled Vocabulary Terms activation of Rap GTPase activity Rap GTPase activator activity
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 28A4-28B2   Limits computationally determined from genome sequence between P{PZ}cuc10607 and P{EP}EP2419EP2419&P{EP}EP575; Limits computationally determined from genome sequence between P{EP}EP2419EP2419&P{EP}EP575 and P{PZ}l(2)rL220rL220
Experimentally Determined Cytological Location
Cytogenetic map Notes References 28B-28B     (Chen, 1997.9.9)
Experimentally Determined Recombination Data
Location	2- (Chen, 1997.9.9)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RapGAP1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47 Gene merge based on EST/cDNA data Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RapGAP1-RD FBtr0334846  NM_144299   4545   933 RapGAP1-RE FBtr0334847  NM_001014478   4951   850 RapGAP1-RF FBtr0334848  NM_001014479   4222   876 RapGAP1-RH FBtr0334849  NM_001103644   4221   959 RapGAP1-RI FBtr0334850  NM_001273279   4462   933
Additional Transcript Data & Comments
Reported size (kB)	4.5 (northern blot) (Chen et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RapGAP1-PD   FBpp0306870   101.3   933   7.19     NP_652556   AAF52528 RapGAP1-PE   FBpp0306871   92.9   850   7.12     NP_001014478   AAF52526 RapGAP1-PF   FBpp0306872   96.1   876   7.39     NP_001014479   AAX52662 RapGAP1-PH   FBpp0306873   104.9   959   7.41     NP_001097114   ABV53642 RapGAP1-PI   FBpp0306874   101.3   933   7.19     NP_001260208   AGB92744
Additional Polypeptide Data & Comments
Reported size (kDa)	850 (aa); 94 (kD predicted) (Chen et al., 1997)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • GoLoco motif (IPR003109) Rap GTPase activating proteins domain (IPR000331)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA567060   AA697924   AE014134 AAF52526   AE014134 AAF52528   AE014134 AAX52662   AE014134 ABV53642   AF023478 AAB87873   AE014134 AGB92744   AI133843   AI296463   AI297556   AI532562   AW941921   AY060820 AAL28368   AY231834   BF487296   BI484804   BI484898   BI623871   BP541456   BT022715   CA805635   CO178311   CO186461   CO191036   CO192671   CO261846   CO263323   CO272520   CO275283   CO280370   CO281125   CO283839   CO283898   CO290042   CO293593   CO293915   CO294762   CO296554   CO302429   CO303971   CO306948   CO311926   CO315501   CO316898   CO318247   CO322153   CO325805   CO327252   CO327627   CO327674   CO328407   CO330395   CO338080   CO340349   CO340600   CZ481569   CZ481570   CZ482401   CZ482402   EC051792   EC052302   EC053314   EC055325   EC056864   EC057060   EC058812   EC060849   EC062610   EC064265   EC065069   EC066771   EC074766   EC075228   EC082161   EC082971   EC084773   EC085952   EC087861   EC204079   EC205038   EC205795   EC207227   EC210535   EC216318   EC225416   EC226794   EC228748   EC229159   EC229653   EC234114   EC236476   EC238448   EC241444   EC242693   EC247268   EC249199   EC253266   EC257067   EC258159   EC259120   EC259191   EC260197   EC266191   EV577493   GH945925   GH949545   GH978147
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q59DZ5 Q9VM00 A8DYW8 O44090 Q95SF4 Q9VM02 Q9VLZ9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References regulatory region FBsf0000435106 2L:7,515,915..7,516,716 evidence=Reporter construct (in vivo) (Aerts et al., 2010, Halfon, 2012.6.19)
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   pole plasm   (Fisher et al., 2012) Comment:maternally deposited organism   • pole plasm (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   anlage in statu nascendi   (Fisher et al., 2012) dorsal ectoderm anlage   (Fisher et al., 2012) Comment:anlage in statu nascendi mesoderm anlage   (Fisher et al., 2012) Comment:anlage in statu nascendi pole cell   (Fisher et al., 2012) ventral ectoderm anlage   (Fisher et al., 2012) Comment:anlage in statu nascendi embryonic stage 7 -- 8   anterior endoderm anlage   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) pole cell   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   antennal primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium central brain primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium visual primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium dorsal head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium lateral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium ventral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium anterior endoderm   (Fisher et al., 2012) germline cell   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) central brain primordium   (Fisher et al., 2012) dorsal epidermis primordium   (Fisher et al., 2012) garland cell primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium visceral muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic/larval garland cell   (Fisher et al., 2012) embryonic/larval lymph gland   (Fisher et al., 2012)
Additional Descriptive Data
	RapGAP1 transcripts are first detected in the posterior pole of the embryo. They are observed in the pole cells as they form. They are detected in pole cells until they migrate through the midgut wall. During germ band extension, they are found in groups of cells in the neurectoderm. After germ band retraction, they are detected in cells of the PNS, in the garland cells and in the gut. In larvae, RapGAP1 transcripts are observed in imaginal discs. In the eye disc, they are observed in most cells of the morphogenetic furrow. Immediate y posterior to the furrow, expression is rapidly restricted to the developing ommatidial clusters. (Chen et al., 1997)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage | early   pole cell   (Chen et al., 1997) embryonic stage 8 -- 11   ventral neurectoderm   (Chen et al., 1997) embryonic stage 13 -- 17   garland cell   (Chen et al., 1997) presumptive embryonic/larval peripheral nervous system   (Chen et al., 1997) embryonic/larval midgut   (Chen et al., 1997) larval stage   embryonic/larval optic lobe   (Chen et al., 1997) optic nerve   • axon (Chen et al., 1997) eye disc   (Chen et al., 1997) morphogenetic furrow   (Chen et al., 1997) morphogenetic furrow | posterior to   (Chen et al., 1997) ommatidial precursor cluster   (Chen et al., 1997)
Additional Descriptive Data
	RapGAP1 protein is first detected in the posterior pole of the embryo in the pole cells as they form. It is detected in pole cells until they migrate through the midgut wall. During germ band extension, RapGAP1 protein is found in groups of cells in the neurectoderm. After germ band retraction, it is detected in cells of the PNS, in the garland cells and in the gut. In larvae, RapGAP1 protein is observed in imaginal discs. In the eye disc, it is observed in most cells of the morphogenetic furrow. Immediately posterior to the furrow expression is rapidly restricted to the developing ommatidial clusters. It is also detected in the axons of the optic nerve and in the optic lobe. (Chen et al., 1997)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    21 central nervous system, pupae P8    32 head, virgin 1-day female    14 head, virgin 4-day female    13 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    19 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    3 fat body, larvae L3 wandering    2 fat body, white prepupae    6 fat body, pupae P8    17 carcass, larvae L3 wandering    11 carcass, 1-day adult    6 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    17 ovary, mated 4-day female    17 testis, mated 4-day male    2 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    21 central nervous system, pupae P8  (32) head, virgin 1-day female    14 head, virgin 4-day female    13 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    19 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    3 fat body, larvae L3 wandering    2 fat body, white prepupae    6 fat body, pupae P8    17 carcass, larvae L3 wandering    11 carcass, 1-day adult    6 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    17 ovary, mated 4-day female    17 testis, mated 4-day male    2 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    21 central nervous system, pupae P8    32 head, virgin 1-day female    14 head, virgin 4-day female    13 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    19 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    3 fat body, larvae L3 wandering    2 fat body, white prepupae    6 fat body, pupae P8    17 carcass, larvae L3 wandering    11 carcass, 1-day adult    6 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    17 ovary, mated 4-day female    17 testis, mated 4-day male    2 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    21 central nervous system, pupae P8    32 head, virgin 1-day female    14 head, virgin 4-day female    13 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    19 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    3 fat body, larvae L3 wandering    2 fat body, white prepupae    6 fat body, pupae P8    17 carcass, larvae L3 wandering    11 carcass, 1-day adult    6 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    17 ovary, mated 4-day female    17 testis, mated 4-day male    2 accessory gland, mated 4-day male    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    21 central nervous system, pupae P8    32 head, virgin 1-day female    14 head, virgin 4-day female    13 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    19 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    3 fat body, larvae L3 wandering    2 fat body, white prepupae    6 fat body, pupae P8    17 carcass, larvae L3 wandering    11 carcass, 1-day adult    6 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    17 ovary, mated 4-day female    17 testis, mated 4-day male    2 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    21 central nervous system, pupae P8  32 head, virgin 1-day female    14 head, virgin 4-day female    13 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    19 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    3 fat body, larvae L3 wandering    2 fat body, white prepupae    6 fat body, pupae P8    17 carcass, larvae L3 wandering    11 carcass, 1-day adult    6 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    17 ovary, mated 4-day female    17 testis, mated 4-day male    2 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    21 central nervous system, pupae P8    32 head, virgin 1-day female    14 head, virgin 4-day female    13 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    19 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    3 fat body, larvae L3 wandering    2 fat body, white prepupae    6 fat body, pupae P8    17 carcass, larvae L3 wandering    11 carcass, 1-day adult    6 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    17 ovary, mated 4-day female    17 testis, mated 4-day male    2 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    9 central nervous system, larvae L3    21 central nervous system, pupae P8    32 head, virgin 1-day female    14 head, virgin 4-day female    13 head, virgin 20-day female    8 head, mated 1-day female    14 head, mated 4-day female    10 head, mated 20-day female    8 head, mated 1-day male    17 head, mated 4-day male    19 head, mated 20-day male    17 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    3 digestive system, 4-day adult    4 digestive system, 20-day adult    3 fat body, larvae L3 wandering    2 fat body, white prepupae    6 fat body, pupae P8    17 carcass, larvae L3 wandering    11 carcass, 1-day adult    6 carcass, 4-day adult    6 carcass, 20-day adult    5 ovary, virgin 4-day female    17 ovary, mated 4-day female    17 testis, mated 4-day male    2 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    18 embryo 04-06hr    36 embryo 06-08hr    36 embryo 08-10hr    30 embryo 10-12hr    17 embryo 12-14hr    27 embryo 14-16hr    28 embryo 16-18hr    30 embryo 18-20hr    23 embryo 20-22hr    13 embryo 22-24hr    15 larva L1    7 larva L2    8 larva L3 12hr old    4 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    7 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    16 pupae 2d postWPP    21 pupae 3d postWPP    21 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    6 adult male 30day    6 adult female 01day    9 adult female 05day    12 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    18 embryo 04-06hr  (36) embryo 06-08hr  (36) embryo 08-10hr  (30) embryo 10-12hr    17 embryo 12-14hr  (27) embryo 14-16hr  (28) embryo 16-18hr  (30) embryo 18-20hr    23 embryo 20-22hr    13 embryo 22-24hr    15 larva L1    7 larva L2    8 larva L3 12hr old    4 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    7 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    16 pupae 2d postWPP    21 pupae 3d postWPP    21 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    6 adult male 30day    6 adult female 01day    9 adult female 05day    12 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    18 embryo 04-06hr    36 embryo 06-08hr    36 embryo 08-10hr    30 embryo 10-12hr    17 embryo 12-14hr    27 embryo 14-16hr    28 embryo 16-18hr    30 embryo 18-20hr    23 embryo 20-22hr    13 embryo 22-24hr    15 larva L1    7 larva L2    8 larva L3 12hr old    4 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    7 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    16 pupae 2d postWPP    21 pupae 3d postWPP    21 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    6 adult male 30day    6 adult female 01day    9 adult female 05day    12 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    18 embryo 04-06hr    36 embryo 06-08hr    36 embryo 08-10hr    30 embryo 10-12hr    17 embryo 12-14hr    27 embryo 14-16hr    28 embryo 16-18hr    30 embryo 18-20hr    23 embryo 20-22hr    13 embryo 22-24hr    15 larva L1    7 larva L2    8 larva L3 12hr old    4 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    7 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    16 pupae 2d postWPP    21 pupae 3d postWPP    21 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    6 adult male 30day    6 adult female 01day    9 adult female 05day    12 adult female 30day    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    18 embryo 04-06hr    36 embryo 06-08hr    36 embryo 08-10hr    30 embryo 10-12hr    17 embryo 12-14hr    27 embryo 14-16hr    28 embryo 16-18hr    30 embryo 18-20hr    23 embryo 20-22hr    13 embryo 22-24hr    15 larva L1    7 larva L2    8 larva L3 12hr old    4 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    7 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    16 pupae 2d postWPP    21 pupae 3d postWPP    21 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    6 adult male 30day    6 adult female 01day    9 adult female 05day    12 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    18 embryo 04-06hr  (36) embryo 06-08hr  (36) embryo 08-10hr  30 embryo 10-12hr    17 embryo 12-14hr  27 embryo 14-16hr  28 embryo 16-18hr  30 embryo 18-20hr    23 embryo 20-22hr    13 embryo 22-24hr    15 larva L1    7 larva L2    8 larva L3 12hr old    4 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    7 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    16 pupae 2d postWPP    21 pupae 3d postWPP    21 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    6 adult male 30day    6 adult female 01day    9 adult female 05day    12 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    18 embryo 04-06hr    36 embryo 06-08hr    36 embryo 08-10hr    30 embryo 10-12hr    17 embryo 12-14hr    27 embryo 14-16hr    28 embryo 16-18hr    30 embryo 18-20hr    23 embryo 20-22hr    13 embryo 22-24hr    15 larva L1    7 larva L2    8 larva L3 12hr old    4 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    7 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    16 pupae 2d postWPP    21 pupae 3d postWPP    21 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    6 adult male 30day    6 adult female 01day    9 adult female 05day    12 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    16 embryo 02-04hr    18 embryo 04-06hr    36 embryo 06-08hr    36 embryo 08-10hr    30 embryo 10-12hr    17 embryo 12-14hr    27 embryo 14-16hr    28 embryo 16-18hr    30 embryo 18-20hr    23 embryo 20-22hr    13 embryo 22-24hr    15 larva L1    7 larva L2    8 larva L3 12hr old    4 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    7 larva L3 puffstage 7-9    9 white prepupae new    12 white prepupae 12hr    15 white prepupae 24hr    16 pupae 2d postWPP    21 pupae 3d postWPP    21 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    6 adult male 30day    6 adult female 01day    9 adult female 05day    12 adult female 30day    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    1 embryonic 1182-4H    3 embryonic GM2    5 embryonic Kc167    4 embryonic S1    7 embryonic S3    5 leg disc CME L1    2 wing disc CME-W2    7 wing disc ML-DmD8    22 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    1 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    10 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    3 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    1 embryonic 1182-4H    3 embryonic GM2    5 embryonic Kc167    4 embryonic S1    7 embryonic S3    5 leg disc CME L1    2 wing disc CME-W2    7 wing disc ML-DmD8    22 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    1 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    10 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    3 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    1 embryonic 1182-4H    3 embryonic GM2    5 embryonic Kc167    4 embryonic S1    7 embryonic S3    5 leg disc CME L1    2 wing disc CME-W2    7 wing disc ML-DmD8    22 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    1 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    10 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    3 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    1 embryonic 1182-4H    3 embryonic GM2    5 embryonic Kc167    4 embryonic S1    7 embryonic S3    5 leg disc CME L1    2 wing disc CME-W2    7 wing disc ML-DmD8    22 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    1 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    10 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    3 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    1 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    1 embryonic 1182-4H    3 embryonic GM2    5 embryonic Kc167    4 embryonic S1    7 embryonic S3    5 leg disc CME L1    2 wing disc CME-W2    7 wing disc ML-DmD8    22 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    1 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    10 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    3 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    1 embryonic 1182-4H    3 embryonic GM2    5 embryonic Kc167    4 embryonic S1    7 embryonic S3    5 leg disc CME L1    2 wing disc CME-W2    7 wing disc ML-DmD8    22 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    1 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    10 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    3 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    1 embryonic 1182-4H    3 embryonic GM2    5 embryonic Kc167    4 embryonic S1    7 embryonic S3    5 leg disc CME L1    2 wing disc CME-W2    7 wing disc ML-DmD8    22 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    1 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    10 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    3 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    2 Schneider line 2 Sg4    1 embryonic 1182-4H    3 embryonic GM2    5 embryonic Kc167    4 embryonic S1    7 embryonic S3    5 leg disc CME L1    2 wing disc CME-W2    7 wing disc ML-DmD8    22 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    16 wing disc ML-DmD21    1 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    10 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    10 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    3 tumorous blood cells mbn2    9 ovary fGS/OSS    5 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    14 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    14 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    14 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    14 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    14 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    14 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    14 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    6 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    14 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    20 Zinc 5 mM 12 hrs, larvae L3    3 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    10 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    6 Paraquat 5 mM 48 hrs, 4-day adult    11 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_31
External Data & Images
Linkouts	BDGP expression data • GM01042
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4da.Switch.PT RapGAP1GX5503-1 viable RapGAP1e04634 viable, with Scer\GAL4pnr-MD237 RapGAP1GD8118 RapGAP1GD12000 Sterility Allele fertile RapGAP1e04634 Other Phenotypes Allele behavior defective | recessive RapGAP1BG01433 visible RapGAP1GMR.PC visible, with Scer\GAL4pnr-MD237 RapGAP1GD12000 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 RapGAP1GD12000 pigment cell RapGAP1GMR.PC trichogen cell, with Scer\GAL4pnr-MD237 RapGAP1GD12000
Classical Alleles ( 33 )
For All Classical Alleles Show
Allele of RapGAP1 Class Mutagen Stocks Known lesion RapGAP1e04634 piggyBac transposase 2 -- RapGAP1LA00889 2 -- RapGAP1BG02277 1 -- RapGAP1c02115 1 -- RapGAP1c02439 1 -- RapGAP1c02661 1 -- RapGAP1c03248 1 -- RapGAP1d11550 1 -- RapGAP1e00163 1 -- RapGAP1e03026 1 -- RapGAP1e03821 piggyBac transposase 1 -- RapGAP1EY03523a 1 -- RapGAP1EY09287 1 -- RapGAP1f03299 1 -- RapGAP1f04374 1 -- RapGAP1f04795 1 -- RapGAP1f06572 1 -- RapGAP1MI07458 1 -- RapGAP1NP1198 1 -- RapGAP1NP6306 1 -- RapGAP122 0 -- RapGAP147 0 -- RapGAP1BG01433 0 -- RapGAP1d06093 0 -- RapGAP1d09127 0 -- RapGAP1d09613 0 -- RapGAP1DG25104 P-element activity 0 -- RapGAP1e03980 0 -- RapGAP1excision loss of function allele P-element activity 0 Yes RapGAP1GS9003 0 Yes RapGAP1GX5503-1 Delta2-3 0 -- RapGAP1MI07759 0 -- RapGAP1SH1453 0 --
Alleles Carried on Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RapGAP1 Class Mutagen Stocks Known lesion RapGAP1GD16772 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes RapGAP1GD12000 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RapGAP1GL01152 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RapGAP1JF01766 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RapGAP1KK105002 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RapGAP1KK109949 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RapGAP1KK110079 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RapGAP1GD15148 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes RapGAP1GD8118 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes RapGAP1GMR.PC in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6018 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}RapGAP1MI07458 NA Mi{MIC}RapGAP1MI07759 NA P{GT1}BG00931 NA P{GT1}RapGAP1BG01433 NA P{GT1}RapGAP1BG02277 NA P{Switch2}GSG176 NA P{UASp-YFP.Rab4}09 NA P{wHy}RapGAP1DG25104 NA PBac{PB}RapGAP1c02115 NA PBac{PB}RapGAP1c02439 NA PBac{PB}RapGAP1c02661 NA PBac{PB}RapGAP1c03248 NA PBac{RB}RapGAP1e00163 NA PBac{RB}RapGAP1e03026 NA PBac{RB}RapGAP1e03821 NA PBac{RB}RapGAP1e03980 NA PBac{RB}RapGAP1e04634 NA PBac{WH}RapGAP1f03299 NA PBac{WH}RapGAP1f04374 NA PBac{WH}RapGAP1f04795 NA PBac{WH}RapGAP1f06572 NA insertion of mobile activating element P{EP}EP575 NA P{EP}EP923 NA P{EP}EP2163 NA P{EP}EP2419EP2419 NA P{EP}EP2579 NA P{EP}EP2625 NA P{EP}RapGAP1GX5503-1 NA P{EPgy2}EY01137a NA P{EPgy2}RapGAP1EY03523a NA P{EPgy2}RapGAP1EY09287 NA P{GSV6}RapGAP1GS9003 NA P{Mae-UAS.6.11}RapGAP1LA00889 NA P{XP}RapGAP1d06093 NA P{XP}RapGAP1d09127 NA P{XP}RapGAP1d09613 NA P{XP}RapGAP1d11550 NA insertion of enhancer trap binary system P{GawB}OK6 No P{GawB}RapGAP1NP1198 No P{GawB}RapGAP1NP6306 No insertion of enhancer trap P{lacW}A1-2-29 No P{lacW}RapGAP1SH1453 No P{PZ}259-179 No P{PZ}rM455 No
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function
CV term Evidence References
Rap GTPase activator activity inferred from direct assay (Chen et al., 1997)
Biological Process
CV term Evidence References
activation of Rap GTPase activity inferred from direct assay (Chen et al., 1997) inter-male aggressive behavior inferred from mutant phenotype (Edwards et al., 2009)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
Ras GTPase activator activity inferred from sequence or structural similarity with NCBI_gi:450641 (FlyBase, 1992-)
Biological Process
CV term Evidence References
Ras protein signal transduction inferred from sequence or structural similarity with human RAP1GAP (FlyBase, 1992-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RapGAP1 allele Gene References Rapgap1GMR.PC R (Chen et al., 1997) unspecified grim (Mueller et al., 2005) H (Mueller et al., 2005) pbl (Gregory et al., 2007) rpr (Mueller et al., 2005)
External Data
Linkouts
Orthologs
OrthoDB Orthologs (57) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6GB7T1, EOG6GQQQG Dipteran inclusive ortholog search EOG632167 Insect inclusive ortholog search EOG6MCVVS Arthropod inclusive ortholog search EOG6WPZJ0 Metazoa inclusive ortholog search EOG68M44C
Orthologs in Drosophila Species (EOG6GB7T1, EOG6GQQQG)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\RapGAP1     Drosophila simulans   Dsim\GD22485 Y   Drosophila simulans   Dsim\GD22487     Drosophila sechellia   Dsec\GM13500 Y   Drosophila sechellia   Dsec\GM13529     Drosophila erecta   Dere\GG23522 Y   Drosophila erecta   Dere\GG23525     Drosophila yakuba   Dyak\GE18348 Y   Drosophila yakuba   Dyak\Rapgap1     Drosophila ananassae   Dana\GF19651 Y   Drosophila ananassae   Dana\GF14020     Drosophila pseudoobscura pseudoobscura   Dpse\GA12532 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA25836     Drosophila persimilis   Dper\GL18864 Y   Drosophila persimilis   Dper\GL18868     Drosophila willistoni   Dwil\GK24371 Y   Drosophila willistoni   Dwil\GK24374     Drosophila virilis   Dvir\GJ23590 Y   Drosophila virilis   Dvir\GJ23610     Drosophila mojavensis   Dmoj\GI23066 Y   Drosophila mojavensis   Dmoj\GI23099     Drosophila grimshawi   Dgri\GH10580 Y   Drosophila grimshawi   Dgri\GH10582
Orthologs in non-Drosophila Dipterans (EOG632167)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL005998   Anopheles gambiae Malaria mosquito  Agam\AGAP009533   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ018142
Orthologs in non-Dipteran Insects (EOG6MCVVS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Rapgap1   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG008207   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH18090   Atta cephalotes Leafcutter ant  Acep\ACEP19426   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17974   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL22667   Linepithema humile Argentine ant  Lhum\LH17239   Pogonomyrmex barbatus Red harvester ant  Pbar\PB11811   Solenopsis invicta Red fire ant  Sinv\SINV22654   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008129   Bombyx mori Silkmoth  Bmor\BGIBMGA008858   Pediculus humanus Human body louse  Phum\PHUM268890   Tribolium castaneum Red flour beetle  Tcas\TC006305
Orthologs in non-Insect Arthropods (EOG6WPZJ0)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\GLA
Orthologs in non-Arthropod Metazoa (EOG68M44C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\F53A10.2   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005447gn   Danio rerio Zebrafish  Drer\ENSDARG00000088735   Danio rerio Zebrafish  Drer\zgc:153898   Danio rerio Zebrafish  Drer\zgc:175145   Danio rerio Zebrafish  Drer\ENSDARG00000053272   Danio rerio Zebrafish  Drer\ENSDARG00000056554   Xenopus tropicalis Western clawed frog  Xtro\rap1gap   Xenopus tropicalis Western clawed frog  Xtro\rap1gap2   Gallus gallus Domestic chicken  Ggal\ENSGALG00000005868   Gallus gallus Domestic chicken  Ggal\RAP1GAP   Mus musculus House mouse  Mmus\Rap1gap2   Mus musculus House mouse  Mmus\Rap1gap   Rattus norvegicus Norway rat  Rnor\Rap1gap   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000002652   Homo sapiens Human  Hsap\RAP1GAP   Homo sapiens Human  Hsap\RAP1GAP2
Human Orthologs (2)
Gene OMIM HGNC Hsap\RAP1GAP     Hsap\RAP1GAP2
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22485 Drosophila sechellia Dsec\GM13500 Drosophila erecta Dere\GG23522 Drosophila yakuba Dyak\GE18348 Drosophila ananassae Dana\GF19651 Drosophila pseudoobscura pseudoobscura Dpse\GA12532 Drosophila persimilis Dper\GL18864 Drosophila willistoni Dwil\GK24371 Drosophila virilis Dvir\GJ23590 Drosophila mojavensis Dmoj\GI23066 Drosophila grimshawi Dgri\GH10580
Stocks & Reagents
Stocks Listed in FlyBase ( 30 )
Harvard	- P{XP}RapGAP1d11550 - PBac{PB}RapGAP1c02115 - PBac{PB}RapGAP1c02439 - PBac{PB}RapGAP1c02661 - PBac{PB}RapGAP1c03248 - PBac{RB}RapGAP1e00163 - PBac{RB}RapGAP1e03026 - PBac{RB}RapGAP1e03821 - PBac{RB}RapGAP1e04634
VDRC	v101846 P{KK109949}VIE-260B v102659 P{KK105002}VIE-260B v106358 P{KK110079}VIE-260B
	More stocks available...
Genomic Clones ( 2 )
	BACR13D17 BACR30I17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 93 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM01042 RE67551
Other clones	yak-em_Rapgap1
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT22056 GH10572 HL03466 LP10375 LP11880 RE67959 RE68074 RH56228 SD04109
Other clones	29301 37829 40188 46190 55981 61989 65799 73645 75279 80615 97035 104016 105222 145188 159940 160414 162527 166473 192380 194080 299370 CK01.1C.B10 CK01.1C.B12 CK01.1D.B10 CK01.13D.F5 CK01.18A.F4 CK01.43B.F8 CK01.62D.F9 CK01.70D.H4 CK01.93C.A2 CK01.105C.F5 CK01.167C.C4 Dmel_dig_008933_0624_3422 EC34259 EC051792 EC052302 EC053314 EC055325 EC253266 EC257067 EC258159 EC259120 EC259191 EK019954 EK050523 EK056362 EK072933 EK080523 EK088223 EK107505 EK117003 EK153910 EK156025 EK164542 EK164747 EK184130 EK187430 EK203809 EK205127 EK207619 EK213959 EK227231 EK243314 EK252837 EK261701 EK266116 EK271147 EK295142 EN15918 EP02548 EP06539 EP07739 EP07839 EP09145 EP10457 EP10958 ESG0119a.B21_A07 FGC001H02 RP004182479 RP004226910 RP004262877
RNAi & Array Information
Linkouts
Antibody Information
	polyclonal (Chen et al., 1997)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Rapgap1 CG6682 (Deng, 1999.11) Source for identity of: RapGAP1 Rapgap1 (FlyBase, 2009-)
Source for database merge of	Source for merge of: Rapgap1 CG13789 (FlyBase Genome Annotators, 2005) Source for merge of: Rapgap1 CG13790 (FlyBase Genome Annotators, 2007) Source for merge of: Rapgap1 CG13791 (FlyBase Genome Annotators, 2012)
Additional comments	Annotations CG34374 and CG13791 merged as CG44086 in release 5.47 of the genome annotation. Merge supported by RNA-seq junction and expression data. (FlyBase Genome Annotators, 2012) FlyBase curator comment: 'Rapgap1' changed to 'RapGAP1' to capitalize the 'GAP' to be consistent with all other GAP gene symbols. (FlyBase, 2009-) Annotations CG33529 and CG13790 merged as CG34374 in release 5.2 of the genome annotation. (FlyBase Genome Annotators, 2007) Annotations CG13789 and CG6682 merged as CG33529 (which corresponds to Rapgap1) in release 4.1 of the genome annotation. (FlyBase Genome Annotators, 2005) "CG13791" may correspond to "Scim14". Sequence analysis off ends of P{SUPor-P} in Scim insertion mutant places "Scim14" near/in "CG13791". (Dobie and Karpen, 2001.4.18)
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Regulation of Rapgap1 mRNA and protein localisation by posterior group genes during the formation of pole plasm is studied. (Chen et al., 1997) Rapgap1 gene product is a GTPase activating protein. (Chen et al., 1995)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_144299 NM_001014478 NM_001014479 NM_001103644 NM_001273279 RefSeq (Proteins) • NP_652556 NP_001014478 NP_001014479 NP_001097114 NP_001260208 DDBJ / EMBL / GenBank • AA567060 AAB87873 AAF52526 AAF52526.1 AAF52527.1 AAF52528 AAF52529 AAL28368 AAN10634.1 AAX52662 ABV53642 AF023478 AGB92744 AW941921 AY060820 CZ481569 CZ481570 CZ482401 CZ482402 Entrez Gene - A searchable database of RefSeq genes. • 34032 34034 UniProtKB/TrEMBL • A8DYW8 O44090 Q9VLZ9 Q9VM00 Q9VM02 Q59DZ5 Q95SF4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • GoLoco motif (IPR003109) Rap GTPase activating proteins domain (IPR000331) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GM01042
Linkouts
Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	CG6682   CG13789   CG13790 (Gregory et al., 2007, Nicholson et al., 2008, Zhang et al., 2007, Manak et al., 2006, Cole et al., 2012.7.6) CG13791 (Nicholson et al., 2008, Zhang et al., 2007, Keleman et al., 2009.8.5, Edwards et al., 2009, Dubruille et al., 2009, Reis et al., 2010, Cole et al., 2012.7.6) CG33529 (Macdonald and Long, 2006, Aerts et al., 2010) CG34374 (FlyBase Genome Annotators, 2007, Keleman et al., 2009.8.5, Ni et al., 2008) CG44086 (Ni et al., 2010.12.1, FlyBase Genome Annotators, 2012) Q9VM02_DROME (Fukuyama et al., 2012) RapGAP1   Rapgap1 (Paik et al., 2012, Lloret-Llinares et al., 2012, Cherbas et al., 2011, Aerts et al., 2010, Foley et al., 2010, Saja et al., 2010, Dubruille et al., 2009, Manak et al., 2006, Sanyal, 2009, Kwon et al., 2008, Bakal et al., 2007, ) RapGap1 (Bakal et al., 2007) rapgap1 (Rangan et al., 2009, Rangan et al., 2008)
Name Synonym	CG13790   Rapgap1 (Kopein and Katanaev, 2009, ) Rap GTPase activating protein 1
Secondary FlyBase IDs
	FBgn0014015 FBgn0031922 FBgn0031923 FBgn0040955 FBgn0053529 FBgn0085403 FBpp0079080 FBpp0079081 FBpp0079082 FBtr0079452 FBtr0079453 FBtr0079454
References ( 65 )
Generate a list of	All references relating to this gene ( 65 )
List References by type	Research paper  ( 27 ) Supplementary material  ( 8 ) Review  ( 1 ) Personal communication to FlyBase  ( 16 ) Abstract  ( 2 ) FlyBase analysis  ( 6 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 3 ) Website  ( 1 )
Recent research papers ( 5 )
	Fukuyama et al., 2012, J. Proteomics 75(15): 4610--4619 On-bead tryptic proteolysis: An attractive procedure for LC-MS/MS analysis of the Drosophila caspase 8 protein complex during immune response against bacteria. [FBrf0218992] Lloret-Llinares et al., 2012, Nucleic Acids Res. 40(19): 9493--9505 dKDM5/LID regulates H3K4me3 dynamics at the transcription-start site (TSS) of actively transcribed developmental genes. [FBrf0219748] Paik et al., 2012, Mech. Ageing Dev. 133(5): 234--245 Misexpression screen delineates novel genes controlling Drosophila lifespan. [FBrf0218389] Weber et al., 2012, PLoS ONE 7(4): e34745 Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073] Cherbas et al., 2011, Genome Res. 21(2): 301--314 The transcriptional diversity of 25 Drosophila cell lines. [FBrf0213077] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...