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Gene Dmel\CG44245

General Information
Symbol	Dmel\CG44245	Species	D. melanogaster
Name		Annotation symbol	CG44245
Feature type	protein_coding_gene	FlyBase ID	FBgn0265180
Gene Model Status	Current	Stock availability	None publicly available
Also Known As	CG9480
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	57D1-57D1	Sequence location	2R:17,087,988..17,100,474 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG44245 (FBgn0265180). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: mesoderm development. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is 2R:17087988..17100474.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 57D1-57D1
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG44245 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49 Certain protein isoforms of two separate genes, Glycogenin and CG44245, share 28 N-terminal residues. Genes with CDS overlap: isoforms of Glycogenin and CG44245 share promoter, first exon and N-terminal coding sequences; overlapping structure not conserved outside of Drosophila. Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG44245-RA FBtr0339094     1836   436 CG44245-RB FBtr0339095     2123   440
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG44245-PA   FBpp0308239   49.2   436   6.04       CG44245-PB   FBpp0308240   49.7   440   5.92
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA801711   AI063314   AI295366   AI389543   BI165948   BI168925   BI213473   BI613651   BI619070   BT001571   BT072855   CO262653   CO271226   CO274145   CO276971   CO278593   CO284209   CO284346   CO298989   CO300266   CO309981   CO312749   CO316349   CO321862   CO323374   CO323821   CO333032   CO341606   CZ471714   CZ490466   EC080415   EC083117   EC087934   EC089395   EC197725   EC205335   EC211978   EC220925   EC221558   EC222658   EC225053   EC231084   EC242530   EC246272   EC248957   EC254524   ES696965   GH941471   GH942172   GH943480   GH944277   GH945246   GH945460   GH946664   GH946676   GH947028   GH947547   GH947594   GH948438   GH951733   GH951766   GH954815   GH958527   GH960058   GH960417   GH965398   GH968385   GH969738   GH974658   GH975926   GH976238   GH976696   GH980032   GH982564   GH982646   GH983539
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Dorus et al., 2006) day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
[an error occurred while processing this directive] FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
[an error occurred while processing this directive]
modENCODE Development RNA-Seq
[an error occurred while processing this directive] modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
[an error occurred while processing this directive]
modENCODE Treatments RNA-Seq
[an error occurred while processing this directive]
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of CG44245 Class Mutagen Stocks Known lesion CG442455-SZ-3612 0 Yes CG442455-SZ-4034 0 -- CG442455-SZ-4120 0 -- CG44245d00632 0 -- CG44245f07729 0 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG44245 Class Mutagen Stocks Known lesion CG44245KK115469 in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS5}Glycogenin5-SZ-3612 NA P{RS5}Glycogenin5-SZ-4034 NA P{RS5}Glycogenin5-SZ-4120 NA PBac{WH}Glycogeninf07729 NA insertion of mobile activating element P{XP}Glycogenind00632 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
	There is no information supporting a cellular component or molecular function term for this gene. (Based on a review of available data on: 2012-10-25)
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mesoderm development inferred from expression pattern (Furlong et al., 2001)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene (FlyBase Genome Annotators, 2012) protein_coding_gene (FlyBase Genome Annotators, 2012)
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG44245 allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (47) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups - Dmel gene model changed subsequent to version 5.45
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG615H0K Dipteran inclusive ortholog search EOG6VX2F3 Insect inclusive ortholog search EOG6WM3QK Arthropod inclusive ortholog search EOG63TXB9 Metazoa inclusive ortholog search EOG664C5Z
Orthologs in Drosophila Species (EOG615H0K)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Glycogenin     Drosophila melanogaster fruit fly  Dmel\CG44245     Drosophila simulans   Dsim\GD11576   Y Drosophila sechellia   Dsec\GM15817   Y Drosophila erecta   Dere\GG22100   Y Drosophila yakuba   Dyak\GE12180   Y Drosophila ananassae   Dana\GF12803   Y Drosophila pseudoobscura pseudoobscura   Dpse\GA21819   Y Drosophila persimilis   Dper\GL11328   Y Drosophila willistoni   Dwil\GK15794   Y Drosophila virilis   Dvir\GJ22086   Y Drosophila mojavensis   Dmoj\GI20361   Y Drosophila grimshawi   Dgri\GH21859   Y
Orthologs in non-Drosophila Dipterans (EOG6VX2F3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014863 Y Anopheles gambiae Malaria mosquito  Agam\AGAP007724 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ013596 Y
Orthologs in non-Dipteran Insects (EOG6WM3QK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB42652 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003411 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14078 Y Atta cephalotes Leafcutter ant  Acep\ACEP27296 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO16362 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18285 Y Linepithema humile Argentine ant  Lhum\LH12589 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB22257 Y Solenopsis invicta Red fire ant  Sinv\SINV25626 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI005296 Y Bombyx mori Silkmoth  Bmor\BGIBMGA002596 Y Pediculus humanus Human body louse  Phum\PHUM407280 Y Tribolium castaneum Red flour beetle  Tcas\TC004671 Y
Orthologs in non-Insect Arthropods (EOG63TXB9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\psbA Y Ixodes scapularis Deer tick  Isca\ISCW006112 Y Ixodes scapularis Deer tick  Isca\ISCW017044 Y Ixodes scapularis Deer tick  Isca\ISCW005321 Y
Orthologs in non-Arthropod Metazoa (EOG664C5Z)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\F56B6.4 Y Caenorhabditis elegans Nematode  Cele\gyg-2 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016241gn Y Danio rerio Zebrafish  Drer\gyg2 Y Danio rerio Zebrafish  Drer\gygl Y Danio rerio Zebrafish  Drer\gyg1 Y Xenopus tropicalis Western clawed frog  Xtro\gyg1 Y Xenopus tropicalis Western clawed frog  Xtro\gyg2 Y Gallus gallus Domestic chicken  Ggal\GYG1 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000016655 Y Mus musculus House mouse  Mmus\Gyg Y Rattus norvegicus Norway rat  Rnor\Gyg1 Y Homo sapiens Human  Hsap\GYG1 Y Homo sapiens Human  Hsap\ENSG00000056998 Y
Human Orthologs (2)
Gene OMIM HGNC Hsap\GYG1     Hsap\ENSG00000056998
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 1 )
	BACR12O13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 72 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE21586
Other clones	MIP06967
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH03053 GH20752 GM03370 LP08970 RE05951 RE09835 RE18880 RH42856 RH50038
Other clones	1292 1356 12498 18513 50155 60242 63619 97716 105007 121244 161190 214247.66 280726 CK01.31A.E12 CK01.102A.F7 EK086024 EK102420 EK113343 EK122530 EK130519 EK165513 EK165839 EK174242 EK177804 EK186549 EK190336 EK191609 EK220121 EK229910 EK264711 EK305514 EP12805 RP004030851 RP004107963 RP004153857 RP004154421 RP004198787 RP004206842 RP004207367 RP004207720 RP004213512 RP004217695 RP004217969 RP004218500 RP004219780 RP004230645 RP004232226 RP004245453 RP004246721 RP004249835 RP004258734 RP004267758 RP004312711 RP004324415 RP004331561 RP004358949 RP004437273 RP004455322 RP004492959 RP004545064 RP004549485
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	Annotation CG9480 split into CG44244 (which corresponds to Glycogenin) and CG44245 in release 5.49 of the genome annotation. The two annotations share a common 5' exon which encodes 3 N-terminal amino acid residues, but otherwise encode two distinct proteins. (FlyBase Genome Annotators, 2012)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	DDBJ / EMBL / GenBank • CZ471714 CZ490466
Other Crossreferences
Linkouts
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG9480 (Cammarato et al., 2011, Arbeitman et al., 2002, Furlong et al., 2001) CG44245 (FlyBase Genome Annotators, 2012)
Name Synonym
Secondary FlyBase IDs
	FBgn0034603
References ( 9 )
Research paper	Liu et al., 2005, Nat. Genet. 37(12): 1361--1366 Sex-specific role of Drosophila melanogaster HP1 in regulating chromatin structure and gene transcription. [FBrf0191273] Arbeitman et al., 2002, Science 297(5590): 2270--2275 Gene expression during the life cycle of Drosophila melanogaster. [FBrf0152339] Furlong et al., 2001, Science 293(5535): 1629--1633 Patterns of gene expression during Drosophila mesoderm development. [FBrf0138533]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] Dorus et al., 2006, Nat. Genet. 38(12): Supplementary Table 1. Genes encoding the Drosophila melanogaster sperm proteome. [FBrf0206129]
FlyBase analysis	FlyBase Genome Annotators, 2012, Changes affecting gene model number or type in release 5.49 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.49 of the annotated D.melanogaster genome. [FBrf0219499] FlyBase Curators, 2010-, Gene Ontology (GO) annotation review. Gene Ontology (GO) annotation review. [FBrf0216433] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]