• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG44252

General Information
Symbol	Dmel\CG44252	Species	D. melanogaster
Name		Annotation symbol	CG44252
Feature type	protein_coding_gene	FlyBase ID	FBgn0265187
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	CG30194
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	59C2-59C2	Sequence location	2R:18,942,997..18,949,072 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG44252 (FBgn0265187). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: fatty acid transporter activity; very long-chain fatty acid-CoA ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process: fatty acid transport. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Gene sequence location is 2R:18942997..18949072.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 59C2-59C2
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG44252 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Genes with CDS overlap: isoforms of CG44252 and CG44253 share promoter, first exon and N-terminal coding sequences; overlapping structure not conserved outside of insects. Certain protein isoforms of two separate genes, CG44252 and CG44253, share 28 N-terminal residues. Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG44252-RB FBtr0339110     2538   703 CG44252-RD FBtr0339109     2651   714 CG44252-RE FBtr0339108     2745   714
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG44252-PB   FBpp0308255   78.3   703   8.88       CG44252-PD   FBpp0308254   78.6   714   8.54       CG44252-PE   FBpp0308253   78.6   714   8.54
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AY084139   BF488896   BF490249   BI483318   BI579411   BI579778   BT031178   BT044476
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 13 -- 16   dorsal head epidermis   (Fisher et al., 2012) embryonic antennal sense organ   (Fisher et al., 2012) embryonic epipharynx   (Fisher et al., 2012) embryonic labial sensory complex   (Fisher et al., 2012) embryonic proventriculus   (Fisher et al., 2012) embryonic salivary gland duct   (Fisher et al., 2012) embryonic/larval posterior spiracle   (Fisher et al., 2012) embryonic/larval salivary gland common duct   (Fisher et al., 2012) labral sensory complex   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
[an error occurred while processing this directive] FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
[an error occurred while processing this directive]
modENCODE Development RNA-Seq
[an error occurred while processing this directive] modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
[an error occurred while processing this directive]
modENCODE Treatments RNA-Seq
[an error occurred while processing this directive]
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG44252c01052 viable, with Scer\GAL4pnr-MD237 CG44252GD2170 Sterility Allele fertile CG44252c01052 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG44252 Class Mutagen Stocks Known lesion CG44252c01052 piggyBac transposase 2 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG44252 Class Mutagen Stocks Known lesion CG44252GD16599 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG44252GD2170 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG44252KK102884 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG44252c01052 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
fatty acid transporter activity inferred from sequence or structural similarity with UniProtKB:Q60714 (Curators, 2008--) very long-chain fatty acid-CoA ligase activity inferred from sequence or structural similarity with UniProtKB:Q60714 (Curators, 2008--)
Biological Process
CV term Evidence References
fatty acid transport inferred from sequence or structural similarity with UniProtKB:Q60714 (Curators, 2008--)
Cellular Component
CV term Evidence References
integral to membrane inferred from sequence model (Curators, 2008--)
Sequence Ontology: Class of Gene
	nuclear_gene (FlyBase Genome Annotators, 2012) protein_coding_gene (FlyBase Genome Annotators, 2012)
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG44252 allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (93) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups - Dmel gene model changed subsequent to version 5.45
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6QJS6S Dipteran inclusive ortholog search EOG666VV4 Insect inclusive ortholog search EOG6W9H0B Arthropod inclusive ortholog search EOG6W3R32 Metazoa inclusive ortholog search EOG6C2W3G
Orthologs in Drosophila Species (EOG6QJS6S)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG44252     Drosophila melanogaster fruit fly  Dmel\CG44253     Drosophila simulans   Dsim\GD11732   Y Drosophila erecta   Dere\GG22821   Y Drosophila yakuba   Dyak\GE14256   Y Drosophila ananassae   Dana\GF13560   Y Drosophila pseudoobscura pseudoobscura   Dpse\GA24654   Y Drosophila persimilis   Dper\GL11230   Y Drosophila willistoni   Dwil\GK19548   Y Drosophila virilis   Dvir\GJ21578   Y Drosophila mojavensis   Dmoj\GI21309   Y Drosophila grimshawi   Dgri\GH20973   Y
Orthologs in non-Drosophila Dipterans (EOG666VV4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000572 Y Anopheles gambiae Malaria mosquito  Agam\AGAP001763 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ007302 Y
Orthologs in non-Dipteran Insects (EOG6W9H0B)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC408920 Y Apis mellifera Western honey bee  Amel\GB45935 Y Apis mellifera Western honey bee  Amel\GB47608 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010460 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG002612 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG002609 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH12820 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14441 Y Atta cephalotes Leafcutter ant  Acep\ACEP26312 Y Atta cephalotes Leafcutter ant  Acep\ACEP22050 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO19581 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO22977 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15307 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL22653 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15306 Y Linepithema humile Argentine ant  Lhum\LH13610 Y Linepithema humile Argentine ant  Lhum\LH12252 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB16358 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB16868 Y Solenopsis invicta Red fire ant  Sinv\SINV13626 Y Solenopsis invicta Red fire ant  Sinv\SINV13034 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI005769 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI007790 Y Bombyx mori Silkmoth  Bmor\BGIBMGA014057 Y Bombyx mori Silkmoth  Bmor\BGIBMGA006185 Y Bombyx mori Silkmoth  Bmor\BGIBMGA006187 Y Bombyx mori Silkmoth  Bmor\BGIBMGA006189 Y Pediculus humanus Human body louse  Phum\PHUM248470 Y Pediculus humanus Human body louse  Phum\PHUM551950 Y Tribolium castaneum Red flour beetle  Tcas\TC009593 Y Tribolium castaneum Red flour beetle  Tcas\TC013521 Y
Orthologs in non-Insect Arthropods (EOG6W3R32)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_193158 Y Ixodes scapularis Deer tick  Isca\ISCW004925 Y Ixodes scapularis Deer tick  Isca\ISCW001799 Y
Orthologs in non-Arthropod Metazoa (EOG6C2W3G)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\acs-20 Y Caenorhabditis elegans Nematode  Cele\acs-22 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_013166gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028572gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016520gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000417gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015837gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_025392gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_015836gn Y Danio rerio Zebrafish  Drer\slc27a2 Y Danio rerio Zebrafish  Drer\ENSDARG00000046054 Y Danio rerio Zebrafish  Drer\slc27a1b Y Danio rerio Zebrafish  Drer\slc27a1a Y Danio rerio Zebrafish  Drer\slc27a4 Y Danio rerio Zebrafish  Drer\zgc:158482 Y Danio rerio Zebrafish  Drer\slc27a6 Y Danio rerio Zebrafish  Drer\LOC100004228 Y Danio rerio Zebrafish  Drer\ENSDARG00000088119 Y Xenopus tropicalis Western clawed frog  Xtro\slc27a2 Y Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000014521 Y Xenopus tropicalis Western clawed frog  Xtro\slc27a3 Y Xenopus tropicalis Western clawed frog  Xtro\slc27a6 Y Gallus gallus Domestic chicken  Ggal\SLC27A6 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000014008 Y Gallus gallus Domestic chicken  Ggal\SLC27A4 Y Gallus gallus Domestic chicken  Ggal\ENSGALG00000013303 Y Mus musculus House mouse  Mmus\Slc27a4 Y Mus musculus House mouse  Mmus\Slc27a3 Y Mus musculus House mouse  Mmus\Slc27a6 Y Mus musculus House mouse  Mmus\Slc27a1 Y Mus musculus House mouse  Mmus\Slc27a5 Y Mus musculus House mouse  Mmus\Slc27a2 Y Rattus norvegicus Norway rat  Rnor\Slc27a1 Y Rattus norvegicus Norway rat  Rnor\Slc27a3 Y Rattus norvegicus Norway rat  Rnor\Slc27a4 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000010128 Y Rattus norvegicus Norway rat  Rnor\Slc27a6 Y Rattus norvegicus Norway rat  Rnor\Slc27a5 Y Homo sapiens Human  Hsap\SLC27A1 Y Homo sapiens Human  Hsap\SLC27A2 Y Homo sapiens Human  Hsap\SLC27A5 Y Homo sapiens Human  Hsap\SLC27A6 Y Homo sapiens Human  Hsap\ENSG00000143554 Y Homo sapiens Human  Hsap\SLC27A4 Y
Human Orthologs (6)
Gene OMIM HGNC Hsap\SLC27A1     Hsap\SLC27A2     Hsap\SLC27A5     Hsap\SLC27A6     Hsap\ENSG00000143554     Hsap\SLC27A4
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	10356 w1118; PBac{PB}CG44252c01052
Harvard	- PBac{PB}CG44252c01052
VDRC	v106140 P{KK102884}VIE-260B v50234 w1118 P{GD16599}v50234 v50235 w1118; P{GD16599}v50235 v3527 w1118; P{GD2170}v3527/CyO v3528 w1118; P{GD2170}v3528/CyO
Genomic Clones ( 2 )
	BACR08P09 BACR37H13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 10 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT18166 RE22703 RE60616
Other clones	DPiM_AT18166 DPiM_RE60616
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT24569 AT26569 RE66190 RE73438 RE73859
Other clones
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG13536 CG3037 (FlyBase Genome Annotators, 2002-2003)
Additional comments	Annotation CG30194 split into CG44252 and CG44253 in release 5.49 of the genome annotation. (FlyBase Genome Annotators, 2012) The two annotations share a common 5' exon which encodes 28 N-terminal amino acid residues, but otherwise encode two distinct proteins. (FlyBase Genome Annotators, 2012) Comments: Annotations CG13536 and CG3037 merged as CG30194 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG30194 (Keleman et al., 2009.8.5, Liu and Lehmann, 2008) CG44252 (FlyBase Genome Annotators, 2012)
Name Synonym
Secondary FlyBase IDs
	FBgn0050194
References ( 12 )
Research paper	Liu and Lehmann, 2008, Insect Mol. Biol. 17(2): 91--101 Genes and biological processes controlled by the Drosophila FOXA orthologue Fork head. [FBrf0204414]
Supplementary material	Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]
FlyBase analysis	FlyBase Genome Annotators, 2012, Changes affecting gene model number or type in release 5.49 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.49 of the annotated D.melanogaster genome. [FBrf0219499] FlyBase Curators, 2010-, Gene Ontology (GO) annotation review. Gene Ontology (GO) annotation review. [FBrf0216433] Curators, 2008--, Assigning Gene Ontology (GO) terms by sequence similarity in FlyBase. Assigning Gene Ontology (GO) terms by sequence similarity in FlyBase. [FBrf0202953] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]