FlyBase Gene Report: Dmel\Atf-2

General Information

Symbol

Dmel\Atf-2

Species

D. melanogaster

Name

Activating transcription factor-2

Annotation Symbol

CG44246

Feature Type

protein_coding_gene

FlyBase ID

FBgn0265193

Gene Model Status

Stock Availability

7 publicly available

Gene Snapshot

Activating transcription factor-2 (Atf-2) encodes a trancription factor required for heterochromatin assembly. It is involved in stress response and fat metabolism regulation. [Date last reviewed: 2019-09-12]

Other Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

ATF2, dATF-2, dATF2

Key Links

Genomic Location

Cytogenetic map

Sequence location

2R:24,870,108..24,871,509 [+]

Recombination map

2-107

RefSeq locus

NT_033778 REGION:24870108..24871509

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (21 terms)

Molecular Function (6 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

enables DNA-binding transcription activator activity, RNA polymerase II-specific

inferred from direct assay

(Okamura et al., 2007, Sano et al., 2005)

enables protein homodimerization activity

inferred from direct assay

(Sano et al., 2005)

enables sequence-specific DNA binding

inferred from direct assay

(Sano et al., 2005)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables cAMP response element binding

inferred from biological aspect of ancestor with PANTHER:PTN001062067

(assigned by GO_Central )

(Gaudet et al., 2011)

enables DNA-binding transcription factor activity, RNA polymerase II-specific

inferred from biological aspect of ancestor with PANTHER:PTN004510459

(assigned by GO_Central )

(Gaudet et al., 2011)

enables RNA polymerase II cis-regulatory region sequence-specific DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN004510459

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (11 terms)

Terms Based on Experimental Evidence (10 terms)

CV Term

Evidence

References

involved_in cellular response to heat

inferred from direct assay

(Seong et al., 2011)

involved_in cellular response to osmotic stress

inferred from direct assay

(Seong et al., 2011, Sano et al., 2005)

involved_in heterochromatin maintenance

inferred from mutant phenotype

(Seong et al., 2011)

involved_in mucosal immune response

inferred from mutant phenotype

(Ha et al., 2009)

involved_in positive regulation of heterochromatin assembly

inferred from mutant phenotype

(Seong et al., 2011)

involved_in positive regulation of transcription by RNA polymerase II

inferred from direct assay

(Okamura et al., 2007, Sano et al., 2005)

involved_in regulation of triglyceride biosynthetic process

inferred from mutant phenotype

(Okamura et al., 2007)

involved_in response to salt stress

inferred from mutant phenotype

(Sano et al., 2005)

involved_in sleep

inferred from mutant phenotype

(Shimizu et al., 2008)

involved_in stress-activated MAPK cascade

inferred from direct assay

(Sano et al., 2005)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in regulation of transcription by RNA polymerase II

inferred from biological aspect of ancestor with PANTHER:PTN004510459

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (4 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

located_in nucleus

inferred from direct assay

(Okamura et al., 2007)

located_in pericentric heterochromatin

inferred from direct assay

(Seong et al., 2011)

located_in polytene chromosome band

inferred from direct assay

(Seong et al., 2011)

located_in polytene chromosome chromocenter

inferred from direct assay

(Seong et al., 2011)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTORS

Protein Family (UniProt)

-

Protein Signatures (InterPro)

Basic-leucine zipper domain

Summaries

Gene Group (FlyBase)

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTORS -: The basic leucine zipper (bZIP) transcription factors are sequence-specific DNA-binding proteins that regulate transcription. They are characterized by a 60-80 amino acid bZIP domain: a basic DNA binding domain followed by a leucine zipper dimerization domain. (Adapted from FBrf0152056).

Summary (Interactive Fly)

Interactive Fly

Gene Model and Products

Number of Transcripts

1

Number of Unique Polypeptides

1

Please see the JBrowse view of Dmel\Atf-2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.49

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.45

Gene model reviewed during 5.40

Sequence Ontology: Class of Gene

(FlyBase Genome Annotators, 2012)

protein_coding_gene

(FlyBase Genome Annotators, 2012)

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0339096

1349

381

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

FBpp0308241

41.9

381

7.33

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Basic-leucine zipper domain

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Atf-2 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Atf-2_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in nucleus

inferred from direct assay

(Okamura et al., 2007)

located_in pericentric heterochromatin

inferred from direct assay

(Seong et al., 2011)

located_in polytene chromosome band

inferred from direct assay

(Seong et al., 2011)

located_in polytene chromosome chromocenter

inferred from direct assay

(Seong et al., 2011)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Atf-2 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Atf-2

View exonic expression by tissue for Dmel\Atf-2

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0265193

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG30420

Images

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 4 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 14 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Atf-2

Transgenic constructs containing regulatory region of Atf-2

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation

Inferred from location

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Other Phenotypes

Allele

abnormal heat stress response

Atf-2^c06407

abnormal immune response

Atf-2^c06407

abnormal immune response, with Scer\GAL4^da.G32

Atf-2^dsRNA.UAS

abnormal locomotor behavior | adult stage

abnormal osmotic stress response, with Scer\GAL4^hs.PB

Atf-2^bZIP.UAS

abnormal stress response

Atf-2^+t13.6

abnormal stress response, with Scer\GAL4^c564

Atf-2^{dsRNA.UAS.cOa}

abnormal stress response, with Scer\GAL4^da.G32

Atf-2^{dsRNA.UAS.cOa}

decreased body size | adult stage, with Scer\GAL4^da.G32

Atf-2^{dsRNA.UAS.cOa}

suppressor of variegation

Atf-2^c06407

suppressor of variegation | maternal effect

Atf-2^c06407

visible, with Scer\GAL4^Bx-MS1096

Atf-2^bZIP.UAS

Phenotype manifest in

Allele

embryonic/larval fat body, with Scer\GAL4^c564

Atf-2^{dsRNA.UAS.cOa}

wing vein, with Scer\GAL4^Bx-MS1096

Atf-2^bZIP.UAS

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (17)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

7 of 15

Yes

Yes

6 of 15

No

Yes

6 of 15

No

Yes

6 of 15

No

Yes

Hsap\ATF7-NPFF

2 of 15

No

Yes

2 of 15

No

No

2 of 15

No

No

2 of 15

No

No

1

1 of 15

No

No

1 of 15

No

No

1

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (15)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

6 of 15

Yes

Yes

6 of 15

Yes

Yes

6 of 15

Yes

Yes

5 of 15

No

Yes

2 of 15

No

No

2 of 15

No

No

2 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

Rattus norvegicus (Norway rat) (12)

5 of 13

Yes

Yes

5 of 13

Yes

Yes

5 of 13

Yes

Yes

4 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

Xenopus tropicalis (Western clawed frog) (10)

4 of 12

Yes

Yes

4 of 12

Yes

Yes

3 of 12

No

Yes

2 of 12

No

No

1 of 12

No

No

1 of 12

No

No

1 of 12

No

No

1 of 12

No

No

1 of 12

No

No

1 of 12

No

No

Danio rerio (Zebrafish) (22)

6 of 15

Yes

Yes

6 of 15

Yes

Yes

6 of 15

Yes

Yes

6 of 15

Yes

Yes

5 of 15

No

Yes

4 of 15

No

Yes

4 of 15

No

Yes

2 of 15

No

No

2 of 15

No

No

2 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

Drer\si:ch211-59d15.4

1 of 15

No

No

Drer\si:ch211-153j24.3

1 of 15

No

No

Caenorhabditis elegans (Nematode, roundworm) (3)

5 of 15

Yes

Yes

3 of 15

No

No

1 of 15

No

No

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (3)

4 of 15

Yes

Yes

3 of 15

No

Yes

2 of 15

No

Yes

Schizosaccharomyces pombe (Fission yeast) (4)

3 of 12

Yes

Yes

3 of 12

Yes

Yes

3 of 12

Yes

Yes

3 of 12

Yes

Yes

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190B5V )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Dsuz\DS10_00003068

Drosophila simulans

Drosophila sechellia

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Drosophila persimilis

Drosophila willistoni

Drosophila virilis

Drosophila grimshawi

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150B8V )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Glossina morsitans

Tsetse fly

Gmor\GMOY009155

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_01615

Mayetiola destructor

Hessian fly

Mdes\Mdes013754

Mayetiola destructor

Hessian fly

Mdes\Mdes002385

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL013261

Anopheles darlingi

American malaria mosquito

Adar\ADAC007609

Anopheles gambiae

Malaria mosquito

Agam\AGAP008416

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ004851

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W072O )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA001375

Danaus plexippus

Monarch butterfly

Dple\DPOGS203627-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL015876

Apis florea

Little honeybee

Aflo\4332725908

Apis mellifera

Western honey bee

Amel\LOC100576527

Bombus impatiens

Common eastern bumble bee

Bombus terrestris

Buff-tailed bumblebee

Linepithema humile

Argentine ant

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:0017bc

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG021820

Dendroctonus ponderosae

Mountain pine beetle

Pediculus humanus

Human body louse

Phum\PHUM600910

Rhodnius prolixus

Kissing bug

Rpro\RPRC010697

Cimex lectularius

Bed bug

Clec\CLEC003972

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI49996

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_01083

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X06XS )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR008245

Ixodes scapularis

Black-legged tick

Isca\ISCW020204

Stegodyphus mimosarum

African social velvet spider

Smim\KFM63135.1

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_324326

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0AO8 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000006645

Gallus gallus

Domestic chicken

Gallus gallus

Domestic chicken

Ggal\ENSGALG00000003038

Gallus gallus

Domestic chicken

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (3)

Gene Symbol

Score

Source

Alignment

2 of 10

2 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

NPDC1; neural proliferation, differentiation and control 1

7 of 15

ATF2; activating transcription factor 2

6 of 15

ATF7; activating transcription factor 7

6 of 15

CREB5; cAMP responsive element binding protein 5

6 of 15

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

fluorescent resonance energy transfer

(Reinke et al., 2013)

two hybrid array

(Shokri et al., 2019)

Atf-2 - Su(var)205

anti bait coimmunoprecipitation, western blot

(Seong et al., 2011)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

enhanceable

(Seong et al., 2011)

suppressible

(Ha et al., 2009)

suppressible

(Sano et al., 2005)

enhanceable

(Sano et al., 2005)

enhanceable

(Seong et al., 2011)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Sano et al., 2005)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0265193

MIST (protein-protein) - An integrated Molecular Interaction Database

Atf-2

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

2R

Recombination map

2-107

Cytogenetic map

Sequence location

2R:24,870,108..24,871,509 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

60E4-60E5

Limits computationally determined from genome sequence between P{EP}Reg-5^EP1065 and P{EP}CG9047^EP560&P{EP}CG3760^EP936

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-107

(FlyBase, 2016)

2-111.7

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (7)

38627

w¹¹¹⁸; PBac{Atf-2-GFP.FLAG}VK00033

85980

w¹¹¹⁸; PBac{PB}Atf-2^c06407

26210

y¹ v¹; P{TRiP.JF02108}attP2

56715

y¹ w^*; Mi{MIC}Atf-2^MI12049

60124

y¹ sc^* v¹ sev²¹; P{TRiP.HMC05118}attP40

v330672

P{VSH330672}attP40

v341977

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD01306}attP40/CyO-GFP

Genomic Clones (15)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (7)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD34489

Other clones

DPiM_LD34489

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0265193

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

37978

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Shimizu et al., 2008)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: Atf-2 CG30420

(Sano, 2005.3.8)

Source for database merge of

Source for merge of: CG12850 CG3749

(FlyBase Genome Annotators, 2002-2003)

Additional comments

Annotation CG30420 split into CG44246 (which corresponds to Atf-2) and CG44247 in release 5.49 of the genome annotation.

(FlyBase Genome Annotators, 2012)

Split based in part on on data from FBrf0188065.

(FlyBase Genome Annotators, 2012)

Annotations CG12850 and CG3749 merged as CG30420 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Other Comments

dsRNA made from templates generated with primers directed against this gene results in embryonic lethality in 17% of cases. These embryos do not show a clear dorsal-open phenotype.

(Sano et al., 2005)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 21 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

37978

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0265193

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0265193

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Atf-2_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG30420

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

37978

InterPro - A database of protein families, domains and functional sites

Basic-leucine zipper domain

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG44246

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0265193

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

MIST (protein-protein) - An integrated Molecular Interaction Database

Atf-2

Synonyms and Secondary IDs (13)

Reported As

Symbol Synonym

ATF-2

(Potdar and Sheeba, 2013, Silver-Morse and Li, 2013, Shimizu et al., 2008)

ATF2

(El Chamy et al., 2015, Wongtrakul et al., 2014, Kuraishi et al., 2013, Lee and Brey, 2013, Igboin et al., 2012, Wongtrakul et al., 2012, Ryu et al., 2010, Ha et al., 2009, Ha et al., 2009)

Atf-2

(Bischof and FlyORF project members, 2019-, Sanuki et al., 2019, Early et al., 2017, Appocher et al., 2014, Das et al., 2013, FlyBase Genome Annotators, 2012, Japanese National Institute of Genetics, 2012.5.21, Mizrak et al., 2012, Spokony and White, 2012.5.22, Kühnlein, 2010)

Atf2

(Makhnovskii et al., 2020, Santabárbara-Ruiz et al., 2015, Appocher et al., 2014, Buchon et al., 2013)

CG12850

(Fassler et al., 2002, Anholt and Mackay, 2001)

CG30420

(Reinke et al., 2013, Perkins et al., 2009.3.31)

CG44246

(Meadows, 2018.10.31, FlyBase Genome Annotators, 2012, Perkins et al., 2009)

DM5

(Reinke et al., 2013)

FBgn0050420

(Shokri et al., 2019)

atf-2

(Chakrabarti et al., 2014)

dATF-2

(Seong et al., 2020, Terriente-Félix et al., 2017, Silver-Morse and Li, 2013, Seong et al., 2011, Shimizu et al., 2008, Okamura et al., 2007, Sano, 2005.3.8, Sano et al., 2005)

dATF2

(Santabárbara-Ruiz et al., 2015, Kohyama-Koganeya et al., 2011)

Name Synonyms

Activating transcription factor-2

(Kühnlein, 2010)

Secondary FlyBase IDs

FBgn0050420
FBgn0035072
FBtr0072381
FBpp0072288
FBtr0072382
FBpp0072289
FBgn0265181

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (65)