A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Gene Dmel\l(3)neo38

General Information
SymbolDmel\l(3)neo38SpeciesD. melanogaster
Namelethal (3) neo38Annotation symbolCG6930
Feature typeprotein_coding_geneFlyBase IDFBgn0265276
Gene Model StatusCurrent Stock availability 22 publicly available
Also Known AsCG14725
Genomic Location
Chromosome (arm)3RRecombination map
Cytogenetic map86E18-86E18Sequence location3R:7,590,760..7,604,850 [-]

Genomic Maps

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Automatically generated summary

See sections below for more information
The gene lethal (3) neo38 is referred to in FlyBase by the symbol Dmel\l(3)neo38 (CG6930, FBgn0265276). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process: regulation of chromatin silencing; imaginal disc-derived wing morphogenesis. 28 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 10 annotated transcripts and 10 annotated polypeptides. Protein features are: Zinc finger C2H2-type/integrase DNA-binding domain; Zinc finger, C2H2; Zinc finger, C2H2-like. Gene sequence location is 3R:7590760..7604850.

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Description
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This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
86E18-86E18  
Limits computationally determined from genome sequence between P{EP}Lk6EP886 and P{PZ}svp07842  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
86F1-86F11  
(determined by in situ hybridisation)  
86F-86F  
(determined by in situ hybridisation)  
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
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Please see the GBrowse view of Dmel\l(3)neo38 for information on other features GBrowse View Help
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0082534 FBtr0082533 FBtr0307082 FBtr0307087 FBtr0110877 FBtr0330170 FBtr0307085 FBtr0307083 FBtr0307086 FBtr0305186 FBtr0110876 FBpp0082008 FBpp0297929 FBpp0297925 FBpp0297928 FBpp0297926 FBpp0082007 FBpp0297930 FBpp0293716 FBpp0110176 FBpp0303203 FBpp0110177 FBti0024389 FBti0103695 FBti0050079 FBti0045171 FBti0108710 FBti0024201 FBti0113143 FBti0103294 FBti0059192 FBti0070323 FBti0077083 FBti0029953 FBti0055030 FBti0011550 FBti0103753 FBti0057527 FBti0104315 FBti0111547 FBti0103691 FBti0059567 FBti0057882 FBti0058902 FBti0113329 FBti0108631 FBti0110350 FBti0112764 FBti0103403 FBti0034617 FBti0034705 FBti0030018 FBti0103139 FBti0111009 FBti0058881 FBti0054181 FBti0021139 FBti0029287 FBti0007862 FBti0008011 FBti0056154 FBti0011676 FBti0112490 FBti0100097 FBti0016513 FBti0011694 FBti0011390 FBti0016548 FBti0110947 FBti0011317 FBti0111318 FBti0033953 FBti0103164 FBti0107095 FBti0105651 FBti0021674 FBti0102567 FBti0109410 FBti0005607 FBti0099765 FBti0111904 FBti0106369 FBti0069086 FBti0028140 FBti0068649 FBti0021417 FBti0043501 FBti0064857 FBti0044406 FBti0036083 FBti0131578 FBti0047123 FBti0005041 FBti0100772 FBti0069677 FBti0070573 FBti0036227 FBti0055160 FBti0034080 FBti0100345 FBti0029737 FBti0029571 FBti0055707 FBti0105759 FBti0108955 FBti0103143 FBti0126541 FBti0044918 FBti0024783 FBti0007998 FBti0112347
Comments on Gene Model
Gene model reviewed during 5.44
Gene model reviewed during 5.49
Stop-codon suppression (UGA) postulated; FBrf0216884.
gene_with_stop_codon_read_through ; SO:0000697
Gene merge based on EST/cDNA data
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0082533
  1522
  380
FBtr0110876
  6236
  447
FBtr0110877
  2247
  447
FBtr0305186
  4963
  434
FBtr0307082
  1417
  373
FBtr0307083
  3815
  360
FBtr0307085
  1414
  373
FBtr0307086
  3691
  360
FBtr0307087
  1611
  447
FBtr0330170
  2247
  455
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
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Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0082007  
40.4  
380  
10.08  
FBpp0110176  
47.1  
447  
10.03  
FBpp0110177  
47.1  
447  
10.03  
FBpp0293716  
45.5  
434  
10.06  
FBpp0297925  
39.6  
373  
10.08  
FBpp0297926  
38.1  
360  
10.10  
FBpp0297928  
39.6  
373  
10.08  
FBpp0297929  
38.1  
360  
10.10  
FBpp0297930  
47.1  
447  
10.03  
FBpp0303203  
48.1  
455  
9.99  
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
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Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
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Crossreferences
hide Expression Data
hideTranscript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
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Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term
References
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Associated Tools
Reference
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
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FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
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modENCODE Temporal Expression Data (Graveley et al., 2011)
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hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
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Linkouts
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
hide Classical Alleles ( 24 )
For All Classical Alleles Show

Allele of l(3)neo38ClassMutagenStocksKnown lesion
l(3)neo3802
1 Yes
l(3)neo3811 Yes
l(3)neo385-HA-1560
1 --
l(3)neo385-HA-1823
1 --
l(3)neo38c01191
1 --
l(3)neo38c03131
1 --
l(3)neo38CB-0491-3
1 --
l(3)neo38d033251 --
l(3)neo38d050101 --
l(3)neo38e014811 --
l(3)neo38KG00059
1 --
l(3)neo38KG01200
1 --
l(3)neo38MI01923
1 --
l(3)neo38NP0970
1 --
l(3)neo38NP4640
1 --
l(3)neo38NP4779
1 --
l(3)neo38[EY07970]1 --
l(3)neo38c00790
0 --
l(3)neo38CA065560 Yes
l(3)neo38d01950
0 --
l(3)neo38d04629
0 --
l(3)neo38d071810 --
l(3)neo38d111570 --
l(3)neo38LAS1460 --
hide Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show

Allele of l(3)neo38ClassMutagenStocksKnown lesion
l(3)neo38GD120762 Yes
l(3)neo38GD171232 Yes
l(3)neo38KK1106841 Yes
l(3)neo38NIG.6930R0 Yes
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Disrupted in
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Transgenic Constructs
Type of construct
Name
Expression data
Insertions
Type of insertions
Name
Expression data
hide Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
hide Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term
References
Cellular Component ( 0 terms)
hide Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term
References
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
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Interacts with
Please look at the allele data for full details of the genetic interactions
l(3)neo38 allele
Gene
References
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Linkouts
hide Orthologs
hide OrthoDB Orthologs (34) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
No orthologs identified
hideOrthologs in Drosophila Species (EOG6NCN02)
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly 
 
 
Drosophila simulans
 
 
 
Drosophila sechellia
 
 
 
Drosophila erecta
 
 
 
Drosophila yakuba
 
 
 
Drosophila ananassae
 
 
 
Drosophila pseudoobscura pseudoobscura
 
 
 
Drosophila persimilis
 
 
 
Drosophila willistoni
 
 
 
Drosophila virilis
 
 
 
Drosophila mojavensis
 
 
 
Drosophila grimshawi
 
 
 
hideOrthologs in non-Drosophila Dipterans (EOG6XD414)
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Aedes aegypti
Yellow fever mosquito 
 
Anopheles gambiae
Malaria mosquito 
 
Culex quinquefasciatus
Southern house mosquito 
 
hideOrthologs in non-Dipteran Insects (EOG608M4F)
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Apis mellifera
Western honey bee 
Amel\GB44350
Y
Apis mellifera
Western honey bee 
Amel\LOC552585
Y
Nasonia vitripennis
Parasitic wasp 
Nvit\Nasvi2EG014269
Y
Nasonia vitripennis
Parasitic wasp 
Nvit\Nasvi2EG014426
Y
Acromyrmex echinatior
Panamanian leafcutter ant 
Aech\AECH23697
Y
Atta cephalotes
Leafcutter ant 
Acep\ACEP27884
Y
Atta cephalotes
Leafcutter ant 
Acep\ACEP27886
Y
Camponotus floridanus
Florida carpenter ant 
Cflo\CFLO25077
Y
Linepithema humile
Argentine ant 
Lhum\LH12771
Y
Pogonomyrmex barbatus
Red harvester ant 
Pbar\PB20879
Y
Solenopsis invicta
Red fire ant 
Sinv\SINV16194
Y
Acyrthosiphon pisum
Pea aphid 
Y
Bombyx mori
Silkmoth 
Y
Bombyx mori
Silkmoth 
Y
Pediculus humanus
Human body louse 
Y
Pediculus humanus
Human body louse 
Y
Tribolium castaneum
Red flour beetle 
Y
Tribolium castaneum
Red flour beetle 
Y
hideOrthologs in non-Insect Arthropods (EOG6X95ZM)
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Daphnia pulex
Water flea 
Y
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
hide Human Orthologs (0)
Gene
OMIM
HGNC
hideAAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
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hide Stocks Listed in FlyBase ( 22 )
Harvard
Kyoto
VDRC
hide Genomic Clones ( 2 )
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 255 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
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Linkouts
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hide Discoverer
A. Spradling.
 
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hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for database merge of
Source for merge of: l(3)neo38 anon-EST:fe2F4
Source for merge of: l(3)neo38 BcDNA:SD16005
Source for merge of: l(3)neo38 CG31364
Additional comments
Source for merge of l(3)neo38 BcDNA:SD16005 was a shared cDNA (date:030728).
hide Other Comments
New annotation (CG31364) in release 3 of the genome annotation. Annotation CG14725 was eliminated in release 3 of the genome annotation, October 2002.
Not created in release 3 of the genome annotation, April 2002. anon-EST:fe2F4 corresponds to no genome annotation - existence reported in FBrf0098343 and FBrf0120351 based on cDNAs primed from genomic runs of As in intronic or intergenic regions.
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Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
Linkouts
hide Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym
anon-EST:fe2F4
 
BcDNA:SD16005
 
Name Synonym
anon-fast-evolving-2F4
 
lethal (3) neo38
 
Secondary FlyBase IDs
  • FBan0006930
  • FBgn0011471
  • FBgn0022340
  • FBgn0037947
  • FBgn0037948
  • FBgn0051364
  • FBgn0062876
  • FBgn0086910
hide References ( 45 )
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hide Recent research papers ( 2 )
Carreira et al., 2011, BMC Dev. Biol. 11: 32
Genetic basis of wing morphogenesis in Drosophila: sexual dimorphism and non-allometric effects of shape variation. [FBrf0214273]
Hoskins et al., 2011, Genome Res. 21(2): 182--192
Genome-wide analysis of promoter architecture in Drosophila melanogaster. [FBrf0213090]