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FB2025_05
,
released December 11, 2025
Please see the JBrowse view of Dmel\drn for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Gene model reviewed during 5.43
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.53
Multiphase exon postulated: this gene shares a region of coding sequence with an overlapping gene, but different reading frames are utilized in the overlapping coding region.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\drn using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
JBrowse - Visual display of RNA-Seq signals
View Dmel\drn in JBrowse3-48
3-46.1
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
New stable cell line derived from S2-unspecified : S2 cell lines expressing circCG32369, circMCPH1, circeIF5B, circrl, circPde11, circCG17715, circzfh2, circTao, circcrol, circdrn, circMeltrin, circpxb, circfru, circdati, circstw, circSarm, circStim, circCG2991, circPvr, circHil, circmub, circsxc, circbnl, and circCG9743 were created. The author reports new stable cell lines S2-circMCPH1, S2-circCG32369, S2-Flag-Ddx56 , and S2-Flag-gw.
Source for merge of: CG43674 anon- EST:fe1B11
Source for merge of: CG33188 BcDNA:RE70963
Source for merge of: CG16750 anon-85Da
Source for merge of: CG43674 CG33937
Annotations CG43674 and CG33937 merged as CG45050 in release 5.53 of the genome annotation; merge based primarily on RNA-Seq junction and coverage data.
Annotation CG33936 split into CG43674 and CG43675 in release 5.43 of the genome annotation.
FlyBase curator comment: Correspondence with author Maeda revealed that 'drn' = 'CG33936'.
Gene order: Overall orientation not stated: Fps85D+ CG8129- CG18473- CG33936-
Annotation CG33187 split into CG33936 and CG33937 in release 4.2 of the genome annotation. In addition, release 4.2 annotation CG33936 contains sequences corresponding to release 4.1 annotation CG33188
Annotation CG33187 split into CG33936 and CG33937 in release 4.2 of the genome annotation. In addition, release 4.2 annotation CG33936 contains sequences corresponding to release 4.1 annotation CG33188.
Annotation CG16751 split into CG33187 and CG33188 in release 3 of the genome annotation. In addition, release 3 annotation CG33188 contains sequences correponding to release 2 annotation CG16750.
Source for merge of CG33188 BcDNA:RE70963 was a shared cDNA ( date:030728 ).
Source for identity of: drn CG45050
Named 'doctor no' after Ian Fleming's fictional character, whose heart was located on the right side of his chest, because the gene is required for normal left-right asymmetric development.
