a member of the exocyst complex - promotes vesicular trafficking involved in cell growth and membrane protein insertion -required for membrane traffic and polarity in the oocyte - mediates embryo cellularization
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
The exocyst complex is composed of Sec3/Exoc1, Sec5/Exoc2, Sec6/Exoc3, Sec8/Exoc4, Sec10/Exoc5, Sec15/Exoc6, Exo70/Exoc7 and Exo84/Exoc8.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sec5 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Sec5 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
sec5 heterozygotes are viable but exhibit a reduced immune response to fungal invasion.
dsRNA directed against this gene causes defects in cytokinesis when tested in an RNAi screen in S2 cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Named "Sec5" after the S. cerevisiae ortholog.