MRE1
Please see the JBrowse view of Dmel\CG45263 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Stop-codon suppression (UAG) postulated (FBrf0222776, FlyBase analysis); supported by conservation of the extended ORF across Drosophila species (FBrf0202906).
Gene model reviewed during 5.56
Gene model reviewed during 5.45
Gene model reviewed during 5.55
Gene model reviewed during 6.02
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.40
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG45263 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: reported as dorsal vessel specific anlage
Comment: reported as dorsal/lateral sensory complexes
Expression pattern inferred from unspecified enhancer trap line.
JBrowse - Visual display of RNA-Seq signals
View Dmel\CG45263 in JBrowse3-48
3-45.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Area matching Drosophila EST AI402854.
Source for merge of: CG31369 CG42285 CG42286
Source for merge of: CG31264 BcDNA:AT05815 anon- EST:Posey178 BcDNA:GH22170
Source for merge of: PQBP-1 CG31264
Source for merge of: PQBP-1 MRE1
Source for merge of: CG43462 CG31462
Annotations CG43462 and CG31462 merged as CG45263 in release 5.56 of the genome annotation, based on RNA-Seq coverage data.
The putative non-coding RNA "MRE1" identified in FBrf0190572 corresponds to the 5'UTR of the CG31369 annotation.
Merge supported by RNA-seq junction and RNA-seq expression data.
Annotations CG31369, CG42285, and CG42286 merged as CG43462 in release 5.40 of the genome annotation.
The gene corresponding to the CG31369 annotation was previously called PQBP-1 (Poly-glutamine tract binding protein 1) in FlyBase, based on the name given in the GenBank accession AJ278495 (which matches part of CG31369 by BLASTN). However, BLAST analysis indicates that CG31369 is not an ortholog of human PQBP-1, and that the D. melanogaster ortholog of human PQBP-1 is CG11820. The gene corresponding to the CG31369 annotation has thus been renamed CG31369 in FlyBase, and the gene corresponding to the CG11820 annotation has been renamed to PQBP1 (as suggested in FBrf0212135).
Annotation CG11718 split into CG42285 and CG42286 in release 5.9 of the genome annotation.
Source for split of: CG11718
Annotation CG11729 split into CG31462 and part of CG31264 in release 3 of the genome annotation. Annotation CG11731 split in release 3 of the genome annotation, corresponding to parts of release 3 annotations CG31264 and CG31369.
Source for merge of CG31264 BcDNA:AT05815 was shared cDNA (AT05815) ( date:030530 ).
