General Information
Symbol
Dmel\rn
Species
D. melanogaster
Name
rotund
Annotation Symbol
CG42277
Feature Type
FlyBase ID
FBgn0267337
Gene Model Status
Stock Availability
Gene Snapshot
Rotund is a member of the Kruppel zinc-finger transcription factor family. It functions as an olfactory neuron specification factor required for diversification of multiple developmental lineages. Its mutants are defective for multiple distal structures in the adult, including smaller legs, wings and eyes. [Date last reviewed: 2016-06-16]
Also Known As
roe, tot, P5.3, tod
Genomic Location
Cytogenetic map
Sequence location
3R:7,272,617..7,309,629 [-]
Recombination map
3-48
Sequence
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
GO Summary Ribbons
Families, Domains and Molecular Function
Gene Group Membership (FlyBase)
Protein Family (UniProt, Sequence Similarities)
Belongs to the krueppel C2H2-type zinc-finger protein family. (Q9VI93)
Summaries
Gene Group Membership
C2H2 ZINC FINGER TRANSCRIPTION FACTORS -
Zinc finger C2H2 transcription factors are sequence-specific DNA binding proteins that regulate transcription. They possess DNA-binding domains that are formed from repeated Cys2His2 zinc finger motifs. (Adapted from PMID:1835093, FBrf0220103 and FBrf0155739).
UniProt Contributed Function Data
Transcription factor involved in imaginal disks development. Isoform rn is required in the wings, antenna, haltere, proboscis and legs disks, while isoform roe is required in the eye disk. Together with nab corepressor, it is involved in the initiation and maintenance of wingless (wg) expression in the wing hinge, by limiting the expression of wg to this compartment. Also required for the epithelial-mesenchymal transition branch of basolateral junctions signaling.
(UniProt, Q9VI93)
Phenotypic Description from the Red Book (Lindsley and Zimm 1992)
rn: rotund (S. Kerridge)
thumb
rn: rotund
From Bridges and Brehme, 1944, Carnegie Inst. Washington Publ. No. 552: 159.
All alleles are viable as homozygotes. Both males and females are sterile; sterility is not germ line dependent. Two transcripts from the rotund region of Drosophila show similar positional specificities in imaginal disc tissues. Adult defects are restricted to homologous distal parts of the appendages, i.e., the antennae, legs, wings, halteres, and proboscis. In the antenna the basal capsule is missing and the third antennal segment is reduced in size; all other antennal and eye disc derivatives are normal. In all three pairs of legs abnormalities caused by the lack of rn+ product are localized specifically in the tarsus; instead of five individual tarsal segments, a single tarsus-like segment differentiates. The distal claw and proximal leg articulations (tibia, femur, trochanter, and coxa) are unaffected. Incomplete and duplicated joints seen at the presumptive positions of the tarsus 1-2 and 4-5 joints; intermediate joints virtually absent (Held, Duarte, and Derakhshanian, 1986, Wilhelm Roux's Arch. Dev Biol. 195: 145-57). Of the wing disc derivatives, the medial and distal costa are fused and the corresponding region in the posterior wing, the alula, is smaller, making the wing as a whole appear shorter; distal wing and mesonotum are formed as in wild type. Vein L5 and to a lesser extent L2 interrupted (rn3). Specific and localized deficiencies of labial and haltere disc derivatives are also evident. Genital and abdominal patterns are indistinguishable from wild-type patterns; however, seminal receptacles shorter than in wild-type females. Examination of the imaginal discs from third-instar rn larvae shows localized cell death in regions determined from fate maps to give rise to distal appendage parts (Cavallin).
rnD: rotund-Dominant
Dominant mutation with complete penetrance and high expressivity. In Dipr/+ flies the distal wing blade reduced to two-thirds normal length; triple row replaced by two to three rows of irregularly sized bristles resembling those found on costa; occasionally these bristles may be bracted as are those of proximal costa. Posterior row of marginal bristles absent distally. Venation in proximal portion of wing irregular and crowded but more nearly normal distally. Trichomes of wing blade organized into whorls. Capitellum of haltere covered with small adventitious bristles and sometimes pedicellar-like sensilla. Pleura, coxa, trochanter, femur, tibia, and fifth tarsal segment unaffected; other tarsal segments reduced; tarsal segments two to four variably fused; ectopic sex combs form on second tarsal segment in 70-90% of forelegs. Basal cylinder of antenna reduced or missing; replaced by bristle elements at third-segment-arista junction resembling those on third segment. Proboscis contains five to seven rows of pseudotracheae rather than normal twelve; replaced by bristles laterally. Kerridge suggests transformation of distal into more proximal appendage elements. Homozygotes survive and are more extreme.
roe: roughened eye
Produces a slight roughening of the eye owing to the irregular disposition of the facets; interommatidial bristles lost from posterior portion of the eye. Extreme expression in mutant/deficiency heterozygotes and more so in deficiency homozygotes; enhanced roughening and posterior loss of ommatidial bristles; in addition the eye is reduced in size and remaining interommatidial bristles are clumped. RK1.
Gene Model and Products
Number of Transcripts
4
Number of Unique Polypeptides
4

Please see the GBrowse view of Dmel\rn or the JBrowse view of Dmel\rn for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model
Gene model reviewed during 5.49
Gene model reviewed during 5.44
Stop-codon suppression (UAG) postulated; FBrf0216884.
gene_with_stop_codon_read_through ; SO:0000697
Due to an oversight in the implementation of gene annotation merges, the symbols for some of the transcripts and polypeptides of this gene were changed to non-unique designations in r5.8. Although there were no conflicts within a given release, the same symbols were used for different isoforms in different releases. The affected gene product symbols have now been changed to symbols not used previously in the database; see individual transcript reports for details.
Gene model reviewed during 5.43
Sequence Ontology: Class of Gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0299637
3565
692
FBtr0300518
5014
946
FBtr0299639
4270
927
FBtr0330140
5014
952
Additional Transcript Data and Comments
Reported size (kB)
1.7 (unknown)
5.3, 1.7 (northern blot)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
FBpp0288912
75.8
692
9.40
FBpp0289745
100.9
946
8.24
FBpp0288914
99.6
927
8.23
FBpp0303173
101.6
952
8.23
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
384, 383 (aa)
384 (aa); 44 (kD)
Comments
It is unclear which ATG is used for translation initiation. If the downstream ATG is the actual initation site, the protein is 362aa and 41kD.
External Data
Subunit Structure (UniProtKB)
Interacts with nab; which acts as a corepressor.
(UniProt, Q9VI93)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\rn using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Gene Ontology (10 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN002553252
(assigned by GO_Central )
Biological Process (6 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
inferred from biological aspect of ancestor with PANTHER:PTN002553252
(assigned by GO_Central )
inferred from sequence or structural similarity with WB:WBGene00003015
Expression Data
Transcript Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
organism

Comment: maternally deposited

adepithelial cell of wing disc

Comment: reference states 0-2 hr APF

antennal disc

Comment: reference states 0-2 hr APF

wing disc

Comment: reference states 0-2 hr APF

haltere disc

Comment: reference states 0-2 hr APF

genital disc

Comment: reference states 0-2 hr APF

labial disc

Comment: reference states 0-2 hr APF

northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
pcr
Stage
Tissue/Position (including subcellular localization)
Reference
RT-PCR
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Detection is shown for isoforms rn-RC, rn-RF and rn-RE. No assay for rn-RG-isoform.
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
wing pouch

Comment: area that corresponds to distal region of wing

Additional Descriptive Data
rn expression is first observed just posterior to the broad stripe of ato expression that is anterior to and within the morphogenetic furrow. rn is initially seen within the first column of nascent R8 nuclei as well as in nuclei surrounding these R8 cells. It then appears to be expressed only in the nuclei immediately surrounding the second column of R8 cells and is no longer expressed near the third column of R8 cells.
Expression first seen in the wing disc during middle to late second instar in an area that corresponds to the distal region of the wing. The nub domain is a bit broader than the rn domain.
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{GawB}rnGAL4-5
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: TI{TI}rnEF.EGFP
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: TI{TI}rnEF.FLAG
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: TI{TI}rnKI.EGFP
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: TI{TI}rnKI.FLAG
Stage
Tissue/Position (including subcellular localization)
Reference
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\rn in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
Images
Alleles, Insertions, Transgenic Constructs and Phenotypes
Classical and Insertion Alleles ( 82 )
For All Classical and Insertion Alleles Show
 
Allele of rn
Class
Mutagen
Associated Insertion
Stocks
Known lesion
Other relevant insertions
Transgenic Constructs ( 9 )
Deletions and Duplications ( 46 )
Summary of Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
Orthologs
Human Orthologs (via DIOPT v7.1)
Homo sapiens (Human) (12)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
3 of 15
Yes
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
No
Model Organism Orthologs (via DIOPT v7.1)
Mus musculus (laboratory mouse) (8)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
3 of 15
Yes
Yes
2 of 15
No
No
1 of 15
No
No
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
Yes
Rattus norvegicus (Norway rat) (9)
2 of 13
Yes
Yes
2 of 13
Yes
Yes
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (3)
1 of 12
Yes
No
1 of 12
Yes
Yes
1 of 12
Yes
Yes
Danio rerio (Zebrafish) (8)
3 of 15
Yes
Yes
3 of 15
Yes
Yes
3 of 15
Yes
Yes
2 of 15
No
Yes
1 of 15
No
Yes
1 of 15
No
No
1 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (6)
5 of 15
Yes
Yes
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (0)
No orthologs reported.
Saccharomyces cerevisiae (Brewer's yeast) (1)
1 of 15
Yes
No
Schizosaccharomyces pombe (Fission yeast) (0)
No orthologs reported.
Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG09190452 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila melanogaster
fruit fly
Drosophila suzukii
Spotted wing Drosophila
Drosophila simulans
Drosophila sechellia
Drosophila erecta
Drosophila yakuba
Drosophila ananassae
Drosophila pseudoobscura pseudoobscura
Drosophila persimilis
Drosophila willistoni
Drosophila virilis
Drosophila mojavensis
Drosophila grimshawi
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091508DI )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Musca domestica
House fly
Glossina morsitans
Tsetse fly
Lucilia cuprina
Australian sheep blowfly
Mayetiola destructor
Hessian fly
Mayetiola destructor
Hessian fly
Aedes aegypti
Yellow fever mosquito
Aedes aegypti
Yellow fever mosquito
Aedes aegypti
Yellow fever mosquito
Anopheles darlingi
American malaria mosquito
Anopheles gambiae
Malaria mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0CP8 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Danaus plexippus
Monarch butterfly
Heliconius melpomene
Postman butterfly
Apis florea
Little honeybee
Apis mellifera
Western honey bee
Bombus impatiens
Common eastern bumble bee
Bombus terrestris
Buff-tailed bumblebee
Linepithema humile
Argentine ant
Nasonia vitripennis
Parasitic wasp
Dendroctonus ponderosae
Mountain pine beetle
Tribolium castaneum
Red flour beetle
Pediculus humanus
Human body louse
Rhodnius prolixus
Kissing bug
Cimex lectularius
Bed bug
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Zootermopsis nevadensis
Nevada dampwood termite
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X08WH )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Stegodyphus mimosarum
African social velvet spider
Tetranychus urticae
Two-spotted spider mite
Daphnia pulex
Water flea
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Human Disease Model Data
FlyBase Human Disease Model Reports
    Alleles Reported to Model Human Disease (Disease Ontology)
    Download
    Models ( 0 )
    Allele
    Disease
    Evidence
    References
    Interactions ( 0 )
    Allele
    Disease
    Interaction
    References
    Comments ( 0 )
     
    Human Orthologs (via DIOPT v7.1)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Interactions Browser

    Please look at the Interaction Group reports for full details of the physical interactions
    RNA-RNA
    Interacting group
    Assay
    References
    Summary of Genetic Interactions
    esyN Network Diagram
    esyN Network Key:
    Suppression
    Enhancement

    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    enhanceable
    External Data
    Subunit Structure (UniProtKB)
    Interacts with nab; which acts as a corepressor.
    (UniProt, Q9VI93 )
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    Pathways
    Gene Group - Pathway Membership (FlyBase)
    External Data
    Linkouts
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    3R
    Recombination map
    3-48
    Cytogenetic map
    Sequence location
    3R:7,272,617..7,309,629 [-]
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    84D3-84D3
    Limits computationally determined from genome sequence between P{EP}EP3060EP3060 and P{PZ}grn05930
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    84D-84E
    (determined by in situ hybridisation)
    84D3-84D4
    (determined by in situ hybridisation)
    Experimentally Determined Recombination Data
    Location
    Left of (cM)
    Right of (cM)
    Notes
    Mapping based on rn3.
    Stocks and Reagents
    Stocks (110)
    Genomic Clones (42)
    cDNA Clones (13)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequences
    BDGP DGC clones
    Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    BDGP DGC clones
      RNAi and Array Information
      Linkouts
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      Antibody Information
      Laboratory Generated Antibodies
      Commercially Available Antibodies
       
      Other Information
      Relationship to Other Genes
      Source for database identify of
      Source for database merge of
      Source for merge of: rn CG32467
      Source for merge of: rn CG14603
      Source for merge of: rn CG10040 CG14600 CG14601
      Source for merge of: rn tot tod
      Additional comments
      Annotations CG32466 and CG32467 merged as CG42277 in release 5.8 of the genome annotation.
      Annotation CG14601 split into CG32467 and part of CG32466 (rn) in release 3 of the genome annotation. Release 3 annotation CG32466 contains sequences corresponding to release 2 annotations CG10040, CG14603, CG14600 and part of CG14601.
      Source for merge of rn CG10040 CG14600 CG14601 was sequence comparison ( date:020121 ).
      The RacGAP84C gene is not responsible for the rn mutant phenotype.
      "rn" and "roe" may correspond to a single gene, since mutations which affect "rn" often also affect "roe", or they may be two closely linked genes.
      "h-NC13" may correspond to "rn"; molecular lesions within the "h-NC13" transcription unit are found in the rnroe-1 and rnroe-2 alleles.
      "rn" shares an intimate relationship with "roe", mutagenesis of one locus often results in simultaneous mutagenesis of the other.
      Other Comments
      RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
      dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
      The rn locus encodes two different transcripts ("rotund" and "roughened eye") which are expressed in non-overlapping domains in the larval imaginal discs. The "rotund" and "roughened eye" proteins share a C-terminus but have unique N-termini. Each transcript can rescue only its corresponding mutation and they show negative effects when expressed in each other's domain of expression. The "rotund" and "roughened eye" phenotypes are genetically separable. In direction of increasing cytology: rn- RacGAP84C+ rn-
      "rn" and "roe" functions of the rn gene are encoded by two transcripts which use different origins of transcription but share the same 3' exons. The proteins encoded by the two transcripts are functionally different; "UAS-rn" constructs can rescue the "rn" phenotype but not "roe", whereas "UAS-roe" constructs rescue "roe" phenotypes but not "rn".
      Expression of rn transcription in rn mutants suggests that the m5.3 transcript encodes rn morphogenetic function in the imaginal discs. Expression partitions all major imaginal discs into domains along the proximo-distal axis: two in the wing and haltere discs, and at least three in the leg and antennae discs. The m5.3 transcript is sex-regulated in the genital disc and is only expressed in the female, suggesting that this disc is organised similar to other imaginal discs. It is not yet clear whether rn function is required for establishment or maintainance of patterning in the proximo-distal axis.
      All alleles are viable as homozygotes. Both males and females are sterile; sterility is not germ line- dependent. Two transcripts from the rotund region of Drosophila show similar positional specificities in imaginal disc tissues. Adult defects are restricted to homologous distal parts of the appendages, i.e., the antennae, legs, wings, halteres and proboscis. In the antenna the basal capsule is missing and the third antennal segment is reduced in size; all other antennal and eye disc derivatives are normal. In all three pairs of legs abnormalities caused by the lack of rn+ product are localized specifically in the tarsus; instead of five individual tarsal segments, a single tarsus-like segment differentiates. The distal claw and proximal leg articulations (tibia, femur, trochanter, and coxa) are unaffected. Incomplete and duplicated joints seen at the presumptive positions of the tarsus 1-2 and 4-5 joints; intermediate joints virtually absent. Of the wing disc derivatives, the medial and distal costa are fused and the corresponding region in the posterior wing, the alula, is smaller, making the wing as a whole appear shorter; distal wing and mesonotum are formed as in wild type. Vein L5 and to a lesser extent L2 interrupted (rn3). Specific and localized deficiencies of labial and haltere disc derivatives are also evident. Genital and abdominal patterns are indistinguishable from wild-type patterns; however, seminal receptacles shorter than in wild-type females. Examination of the imaginal discs from third instar rn larvae shows localized cell death in regions determined from fate maps to give rise to distal appendage parts.
      rn mutants lack structures in the distal parts of all appendages.
      The abnormal rn phenotype is due to a developmental defect: late occurring defects. Adult eye is rough and slightly reduced, eye disc pattern appears normal.
      Clonal analysis demonstrates that the rn gene is required for normal morphogenesis of specific distal parts of the adult appendages.
      Origin and Etymology
      Discoverer
      Etymology
      Named for transformation of T1 type trichoid sensillae on the antennae to non T1 type trichoid sensillae.
      Named for lack of T1 type trichoid sensillae on the antennae.
      Identification
      External Crossreferences and Linkouts ( 38 )
      Crossreferences
      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
      UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
      UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
      Other crossreferences
      BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
      InterPro - A database of protein families, domains and functional sites
      Linkouts
      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center cDNA clones
      DroID - A comprehensive database of gene and protein interactions.
      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
      iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
      Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
      KEGG Genes - Molecular building blocks of life in the genomic space.
      Synonyms and Secondary IDs (21)
      Reported As
      Symbol Synonym
      CG14600
      CG14601
      CG14603
      Dipr
      Secondary FlyBase IDs
      • FBgn0259172
      • FBgn0003263
      • FBgn0003269
      • FBgn0037494
      • FBgn0037495
      • FBgn0037496
      • FBgn0037497
      • FBgn0052466
      • FBgn0052467
      • FBgn0260876
      • FBgn0260875
      Datasets (0)
      Study focus (0)
      Experimental Role
      Project
      Project Type
      Title
      References (156)