AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 6.03
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\PRAS40 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\PRAS40 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: PRAS40 CG46146
FBrf0151277 reports that the L (Lobe) mutant complementation group corresponds to the CG10109 annotation (based on the ability of a CG10109 construct to rescue L mutant phenotypes and mapping of the lesion in a L mutant). However, FBrf0217295 reports that L does not correspond to the CG10109 annotation (based on the failure to of a CG10109 construct to rescue L mutant phenotypes and the viability of a L mutant allele over a deficiency that removes CG10109). The L (Lobe) mutant complementation group has been split out from the CG10109 annotation in FlyBase until this is resolved. Thus, in release 6.03 of the genome annotation, annotation CG46146 replaces CG10109 and is split from the Lobe (L) gene.