FB2025_05 , released December 11, 2025
Gene: Dmel\vib
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General Information
Symbol
Dmel\vib
Species
D. melanogaster
Name
vibrator
Annotation Symbol
CG5269
Feature Type
protein_coding_gene
FlyBase ID
FBgn0267975
Gene Model Status
Current
Stock Availability
15 publicly available
Gene Summary
vibrator (vib) is an essential gene that encodes a conserved phosphatidylinositol transfer protein. The vib protein is enriched at the cleavage furrow and it is required for cytokinesis. [Date last reviewed: 2019-03-21] (FlyBase Gene Snapshot)
All Summaries
Also Known As

gio, giotto, PITP, l(3)j7A3, l(3)j4A3

Key Links
Genomic Location
Cytogenetic map
91F11-91F12
Sequence location
Recombination map
3-66
RefSeq locus
NT_033777 REGION:19215434..19226651
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (22 terms)
Molecular Function (5 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (5 terms)
CV Term
Evidence
References
enables phosphatidylcholine binding
inferred from biological aspect of ancestor with PANTHER:PTN000069712
(GO Reference Genome Project, 2011-)
enables phosphatidylcholine transporter activity
inferred from biological aspect of ancestor with PANTHER:PTN000069712
(GO Reference Genome Project, 2011-)
enables phosphatidylinositol binding
inferred from biological aspect of ancestor with PANTHER:PTN000069712
(GO Reference Genome Project, 2011-)
enables phosphatidylinositol transfer activity
inferred from biological aspect of ancestor with PANTHER:PTN000069712
(GO Reference Genome Project, 2011-)
enables phospholipid transporter activity
inferred from electronic annotation with InterPro:IPR001666
(InterPro Project Members, 2004-)
Biological Process (10 terms)
Terms Based on Experimental Evidence (9 terms)
CV Term
Evidence
References
involved_in actomyosin contractile ring contraction
inferred from mutant phenotype
(Giansanti et al., 2004)
involved_in cleavage furrow ingression
inferred from mutant phenotype
(Gatt and Glover, 2006, Giansanti et al., 2006)
involved_in male meiosis cytokinesis
inferred from mutant phenotype
(Giansanti et al., 2007)
involved_in meiosis I cytokinesis
inferred from mutant phenotype
(Giansanti et al., 2004)
involved_in meiosis II cytokinesis
inferred from mutant phenotype
(Giansanti et al., 2004)
involved_in meiotic cytokinesis
inferred from mutant phenotype
(Gatt and Glover, 2006, Giansanti et al., 2006)
involved_in meiotic spindle organization
inferred from mutant phenotype
(Giansanti et al., 2004)
involved_in spermatocyte division
inferred from mutant phenotype
(Giansanti et al., 2007)
involved_in spermatogenesis
inferred from mutant phenotype
(Gatt and Glover, 2006)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in phospholipid transport
inferred from electronic annotation with InterPro:IPR001666
(InterPro Project Members, 2004-)
Cellular Component (7 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
located_in cleavage furrow
inferred from direct assay
(Belloni et al., 2012, Giansanti et al., 2006)
located_in Golgi apparatus
inferred from direct assay
(Belloni et al., 2012)
located_in Nebenkern
inferred from direct assay
(Gatt and Glover, 2006)
located_in nuclear membrane
inferred from direct assay
(Gatt and Glover, 2006)
located_in plasma membrane
inferred from direct assay
(Gatt and Glover, 2006)
located_in spindle envelope
inferred from direct assay
(Belloni et al., 2012, Giansanti et al., 2006)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000069712
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
vibrator (vib) is an essential gene that encodes a conserved phosphatidylinositol transfer protein. The vib protein is enriched at the cleavage furrow and it is required for cytokinesis. [Date last reviewed: 2019-03-21]
Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
2

Please see the JBrowse view of Dmel\vib for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry A0A0B4KGG5)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.54

Gene model reviewed during 5.42

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
vib-RA
FBtr0083745
NM_079680
1178
272
vib-RB
FBtr0310064
NM_001275797
3491
273
vib-RC
FBtr0344554
NM_001300473
3395
272
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
vib-PA
FBpp0083159
31.3
272
5.94
Q9VDY8
NP_524404
AAF55650
vib-PB
FBpp0301765
31.6
273
5.68
A0A0B4KGG5
NP_001262726
AGB96106
vib-PC
FBpp0310907
31.3
272
5.94
Q9VDY8
NP_001287402
AHN57401
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

272 aa isoforms: vib-PA, vib-PC
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\vib using the Feature Mapper tool.

External Data
Crossreferences
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-1.60

Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage | male & spermatogenesis
primary spermatocyte in meiotic telophase I
(Belloni et al., 2012)
secondary spermatocyte in meiotic telophase II
(Belloni et al., 2012)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in cleavage furrow
inferred from direct assay
(Belloni et al., 2012, Giansanti et al., 2006)
located_in Golgi apparatus
inferred from direct assay
(Belloni et al., 2012)
located_in Nebenkern
inferred from direct assay
(Gatt and Glover, 2006)
located_in nuclear membrane
inferred from direct assay
(Gatt and Glover, 2006)
located_in plasma membrane
inferred from direct assay
(Gatt and Glover, 2006)
located_in spindle envelope
inferred from direct assay
(Belloni et al., 2012, Giansanti et al., 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\vib in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 28 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 13 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of vib
Transgenic constructs containing regulatory region of vib
Aberrations (Deficiencies and Duplications) ( 1 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal | embryonic stage | maternal effect
lethal | recessive
lethal - all die before end of larval stage (with Df(3R)BSC850)
lethal - all die before end of P-stage
lethal - all die before end of P-stage (with Df(3R)Delta-BX12)
lethal - all die before end of pupal stage
lethal - all die before end of pupal stage (with Df(3R)Delta-BX12)
lethal - all die before end of second instar larval stage
lethal - all die before end of second instar larval stage (with Df(3R)BSC850)
lethal - all die before end of second instar larval stage (with Df(3R)Delta-BX12)
lethal - all die during embryonic stage
viable
viable (with Df(3R)Delta-BX12)
Sterility
Allele
female fertile (with Df(3R)Delta-BX12)
fertile (with Df(3R)Delta-BX12)
male sterile
male sterile (with Df(3R)Delta-BX12)
sterile (with Df(3R)Delta-BX12)
Other Phenotypes
Allele
abnormal cell number | larval stage | somatic clone
abnormal cell polarity | larval stage (with Df(3R)BSC850)
abnormal cell polarity | larval stage (with vib133)
abnormal cell polarity | larval stage (with vib1105)
abnormal cell polarity | larval stage (with vibj5A6)
abnormal cytokinesis
abnormal cytokinesis (with Df(3R)Delta-BX12)
abnormal cytokinesis (with vibS045002c)
abnormal cytokinesis (with vibS110416)
abnormal cytokinesis | larval stage (with vib133)
abnormal cytokinesis | larval stage (with vibj5A6)
abnormal cytokinesis | male
abnormal cytokinesis | male (with Df(3R)Delta-BX12)
abnormal cytokinesis | male | recessive
abnormal meiotic cell cycle (with Df(3R)Delta-BX12)
abnormal meiotic cell cycle | male (with Df(3R)Delta-BX12)
abnormal meiotic cell cycle | male | recessive
abnormal mitotic cell cycle | male | recessive
decreased cell number | larval stage | somatic clone
decreased cell size | larval stage | somatic clone
increased cell number | larval stage | somatic clone
some die during embryonic stage
some die during pharate adult stage
some die during pharate adult stage (with Df(3R)Delta-BX12)
some die during pupal stage
some die during pupal stage (with Df(3R)Delta-BX12)
some die during second instar larval stage
some die during second instar larval stage (with Df(3R)Delta-BX12)
Phenotype manifest in
Allele
contractile ring & meiotic telophase I | male
contractile ring & meiotic telophase I | male (with Df(3R)Delta-BX12)
contractile ring & meiotic telophase II | male
contractile ring & meiotic telophase II | male (with Df(3R)Delta-BX12)
embryonic/first instar larval cuticle | maternal effect
head | maternal effect
larval brain
larval brain | larval stage (with vib133)
larval brain | larval stage (with vibj5A6)
larval brain | larval stage | somatic clone
larval neuroblast (with Df(3R)Delta-BX12)
Nebenkern
Nebenkern (with Df(3R)Delta-BX12)
neuroblast | larval stage (with Df(3R)BSC850)
neuroblast | larval stage (with vib133)
neuroblast | larval stage (with vib1105)
neuroblast | larval stage (with vibj5A6)
secondary spermatocyte (with Df(3R)Delta-BX12)
spermatid
spermatid (with Df(3R)Delta-BX12)
spermatid & nucleus | supernumerary
spermatid & nucleus | supernumerary (with Df(3R)Delta-BX12)
spermatocyte ring canal (with Df(3R)Delta-BX12)
spermatozoon
spindle
spindle & meiotic telophase I | male
spindle & meiotic telophase I | male (with Df(3R)Delta-BX12)
spindle & meiotic telophase II | male
spindle & meiotic telophase II | male (with Df(3R)Delta-BX12)
type II neuroblast | larval stage | somatic clone
type I neuroblast | larval stage | somatic clone
ventral denticle belt | embryonic stage | maternal effect
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (9)
Hsap\PITPNB
13 of 14
Yes
Yes
1  
Hsap\PITPNA
12 of 14
No
Yes
1  
Hsap\PITPNC1
3 of 14
No
No
Hsap\PITPNM1
2 of 14
No
No
Hsap\PITPNM2
2 of 14
No
No
Hsap\LPIN1
1 of 14
No
No
Hsap\LPIN2
1 of 14
No
No
Hsap\LPIN3
1 of 14
No
No
Hsap\PITPNM3
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (8)
Rnor\Pitpnb
13 of 14
Yes
Yes
Rnor\Pitpna
11 of 14
No
Yes
Rnor\Pitpnm1
2 of 14
No
No
Rnor\Pitpnm2
2 of 14
No
No
Rnor\Lpin1
1 of 14
No
No
Rnor\Lpin2
1 of 14
No
No
Rnor\Lpin3
1 of 14
No
No
Rnor\Pitpnc1
1 of 14
No
No
Mus musculus (laboratory mouse) (9)
Mmus\Pitpna
12 of 14
Yes
Yes
Mmus\Pitpnb
12 of 14
Yes
Yes
Mmus\Pitpnc1
3 of 14
No
No
Mmus\Pitpnm1
2 of 14
No
No
Mmus\Pitpnm2
2 of 14
No
No
Mmus\Lpin1
1 of 14
No
No
Mmus\Lpin2
1 of 14
No
No
Mmus\Lpin3
1 of 14
No
No
Mmus\Pitpnm3
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (10)
Xtro\pitpnb.2
11 of 13
Yes
Yes
Xtro\pitpnb
10 of 13
No
Yes
Xtro\pitpna
6 of 13
No
Yes
Xtro\pitpnc1
2 of 13
No
No
Xtro\ebf3
1 of 13
No
No
Xtro\LOC100493137
1 of 13
No
No
Xtro\osbpl9
1 of 13
No
No
Xtro\pitpnc1l
1 of 13
No
No
Xtro\pitpnm2
1 of 13
No
No
Xtro\reep6
1 of 13
No
No
Danio rerio (Zebrafish) (9)
Drer\pitpnb
13 of 14
Yes
Yes
Drer\pitpnaa
12 of 14
No
Yes
Drer\pitpnbl
12 of 14
No
Yes
Drer\pitpnab
10 of 14
No
Yes
Drer\pitpnc1b
3 of 14
No
No
Drer\pitpnc1a
2 of 14
No
No
Drer\lpin1a
1 of 14
No
No
Drer\pitpnm2
1 of 14
No
No
Drer\pitpnm3
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (4)
Cele\Y54F10AR.1
13 of 14
Yes
Yes
Cele\Y71G12B.17
4 of 14
No
No
Cele\pitp-1
2 of 14
No
No
Cele\lpin-1
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (4)
Agam\AgaP_AGAP001957
11 of 12
Yes
Yes
Agam\AgaP_AGAP000033
3 of 12
No
No
Agam\AgaP_AGAP004469
2 of 12
No
No
Agam\AgaP_AGAP007636
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (2)
Atha\PAH1
1 of 13
Yes
No
Atha\PAH2
1 of 13
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\PAH1
1 of 13
Yes
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\ned1
1 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:vib. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (3)
rdgBβ
5 of 13
rdgB
5 of 13
Lpin
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 2 )
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    PITPNB; phosphatidylinositol transfer protein beta
    13 of 14
    606876
         
        PITPNA; phosphatidylinositol transfer protein alpha
        12 of 14
        600174
             
            PITPNC1; phosphatidylinositol transfer protein cytoplasmic 1
            3 of 14
            605134
                Functional Complementation Data
                Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                Interactions
                Summary of Physical Interactions
                Summary of Genetic Interactions
                Interaction Browsers
                View in FlyBase Interactions Browser   View in MIST tool (external link)
                Please look at the allele data for full details of the genetic interactions
                Starting gene(s)
                Interaction type
                Interacting gene(s)
                Reference
                Starting gene(s)
                Interaction type
                Interacting gene(s)
                Reference
                pbl
                suppressible
                vib
                (Gregory et al., 2007)
                External Data
                Linkouts
                MIST (protein-protein) - An integrated Molecular Interaction Database
                Pathways
                Signaling Pathways (FlyBase)
                Metabolic Pathways
                FlyBase
                External Links
                Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.
                External Data
                Linkouts
                Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                Class of Gene
                Genomic Location and Detailed Mapping Data
                Chromosome (arm)
                3R
                Recombination map
                3-66
                Cytogenetic map
                91F11-91F12
                Sequence location
                FlyBase Computed Cytological Location
                Cytogenetic map
                Evidence for location
                91F11-91F12
                Left limit from in situ hybridisation (FBrf0067338) Right limit from in situ hybridisation (FBrf0067338); Limits computationally determined from genome sequence between P{EP}EP650 and P{PZ}l(3)1058510585
                Experimentally Determined Cytological Location
                Cytogenetic map
                Notes
                References
                Location based on deficiency mapping.
                (Giansanti et al., 2004)
                91F1-92D6
                (Giansanti et al., 2004)
                91F10-91F11
                (Spana, 2000.3.18)
                91F10-91F11
                (determined by in situ hybridisation)
                (Spradling et al., 1999, Perrimon et al., 1996)
                92A-92A
                (determined by in situ hybridisation)
                (Szeged Stock Center, 1998-)
                91F10-91F13
                (determined by in situ hybridisation)
                (Deak et al., 1997)
                91F11-91F12
                (BDGP Project Members, 1994-1999)
                Experimentally Determined Recombination Data
                Location

                3-66

                (FlyBase, 2016)

                3-66.1

                (Comeron et al., 2012)

                3-

                (Giansanti et al., 2004)
                Left of (cM)
                Right of (cM)
                Notes
                Stocks and Reagents
                Stocks (15)
                Genomic Clones (16)
                 

                Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                cDNA Clones (183)
                 

                Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

                cDNA clones, fully sequenced
                BDGP DGC clones
                Other clones
                Drosophila Genomics Resource Center cDNA clones

                For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                cDNA Clones, End Sequenced (ESTs)
                BDGP DGC clones
                Other clones
                RNAi and Array Information
                Linkouts
                Antibody Information
                Laboratory Generated Antibodies
                 

                polyclonal

                (Koe et al., 2018, Gatt and Glover, 2006, Giansanti et al., 2006)
                Commercially Available Antibodies
                 
                Cell Line Information
                Publicly Available Cell Lines
                 
                  Other Stable Cell Lines
                   
                    Other Comments

                    vib has a number of roles throughout development. These roles may be separated into two classes: actin based processes and signal transduction processes.

                    (Spana and Perrimon, 1999)

                    vib mutants show phenotypes in oogenesis (collapsed ring canals), bristle differentiation (unpigmented, flaccid bristles) and hair production (multiple hairs per cell).

                    (Spana and Perrimon, 1999)

                    The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation.

                    (Perrimon et al., 1996)
                    Relationship to Other Genes
                    Source for database merge of

                    Source for merge of: vib anon-WO0142479.3 anon-WO0172774.12 anon-WO0172774.16 anon-WO0172774.28

                    (FlyBase, 1996-)

                    Source for merge of: vib CG5269

                    (FlyBase, 1996-)

                    Source for merge of: l(3)j5A6 l(3)j4A3 l(3)j7A3

                    (Beaton, 1999.12.12)

                    Source for merge of: vib gio l(3)j5A6

                    (Giansanti et al., 2006)

                    Source for merge of: vib l(3)S045002c l(3)S110416

                    (Gatt and Glover, 2006)

                    Source for merge of: vib PITP

                    (FlyBase, 1996-)
                    Additional comments

                    Source for merge of vib anon-WO0142479.3 anon-WO0172774.12 anon-WO0172774.16 anon-WO0172774.28 was sequence comparison ( date:051113 ).

                    (FlyBase, 1996-)

                    Source for merge of vib CG5269 was sequence comparison ( date:000401 ).

                    (FlyBase, 1996-)

                    Source for merge of vib PITP was that FBrf0112171 states that 'PITP' corresponds to cDNA clone HL04023, and HL04023 corresponds to CG5269 (vib) by BLAST against the release 6 genome (date: 141028).

                    (FlyBase, 1996-)
                    Nomenclature History
                    Source for database identify of
                    Nomenclature comments
                    Etymology
                    Synonyms and Secondary IDs (27)
                    Reported As
                    Symbol Synonym
                    0450/02
                    (Deak et al., 1997)
                    1104/16
                    (Deak et al., 1997)
                    CG5269
                    (Trivedi et al., 2020, Meadows, 2018.10.31, Cockcroft and Raghu, 2016, Jiang et al., 2016, Cammarato et al., 2011, Monzo et al., 2010, Puri et al., 2008, Giansanti et al., 2006, Giansanti et al., 2006)
                    Dm-PITPα
                    (Yadav et al., 2015)
                    Gio
                    (Frappaolo et al., 2017)
                    PITP
                    (Cockcroft and Raghu, 2016, Cockcroft et al., 2016)
                    PITP-DM
                    (Fullwood et al., 1999)
                    Vib
                    (Deng and Wang, 2022, Puri et al., 2008)
                    anon-WO0142479.3
                    anon-WO0172774.12
                    anon-WO0172774.16
                    anon-WO0172774.28
                    gio
                    (Balakrishnan et al., 2015, Belloni et al., 2012, Giansanti and Fuller, 2012, Giansanti et al., 2012, Lesch and Page, 2012, Giansanti et al., 2007, Giansanti et al., 2006, Giansanti et al., 2006)
                    giotto
                    (Thanh et al., 2020)
                    l(3)S045002
                    l(3)S045002c
                    l(3)S110416
                    l(3)j4A3
                    (BDGP Project Members, 1994-1999)
                    l(3)j5A6
                    (Giansanti et al., 2006)
                    l(3)j7A3
                    (BDGP Project Members, 1994-1999)
                    l(3)j7C8
                    vib
                    (Wang et al., 2020, Abruzzi et al., 2017, Cockcroft and Raghu, 2016, Balakrishnan et al., 2015, Del Caño-Espinel et al., 2015, Gene Disruption Project members, 2015-, Yadav et al., 2015, Ashwal-Fluss et al., 2014, Luck et al., 2014, Japanese National Institute of Genetics, 2012.5.21, Monzo et al., 2010, Branco et al., 2008, Buszczak et al., 2007, Giansanti et al., 2006, Giansanti et al., 2006)
                    Name Synonyms
                    PITP
                    Vibrator
                    (Giansanti et al., 2012, Branco et al., 2008)
                    giotto
                    (Belloni et al., 2012, Lesch and Page, 2012, Giansanti et al., 2007, Gregory et al., 2007, Giansanti et al., 2006, Giansanti et al., 2004)
                    lethal (3) S045002c
                    lethal (3) S110416
                    lethal (3) j5A6
                    vibrator
                    (Thanh et al., 2020, Yuan et al., 2019, Cammarato et al., 2011, Gatt and Glover, 2006, Giansanti et al., 2006, Spana and Perrimon, 1999)
                    Secondary FlyBase IDs
                    • FBgn0262468
                    • FBgn0260992
                    • FBgn0026158
                    • FBgn0038689
                    • FBgn0044524
                    • FBgn0046402
                    • FBgn0046440
                    • FBgn0046474
                    • FBgn0083089
                    • FBgn0011376
                    • FBgn0011359
                    • FBgn0011404
                    • FBgn0024527
                    • FBgn0028148
                    • FBgn0028011
                    • FBgn0028702
                    Datasets (0)
                    Study focus (0)
                    Experimental Role
                    Project
                    Project Type
                    Title
                    Study result (0)
                    Result
                    Result Type
                    Title
                    External Crossreferences and Linkouts ( 56 )
                    Sequence Crossreferences
                    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                    UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                    Other crossreferences
                    AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                    DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                    EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                    FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                    InterPro - A database of protein families, domains and functional sites
                    KEGG Genes - Molecular building blocks of life in the genomic space.
                    MARRVEL_MODEL - MARRVEL (model organism gene)
                    Linkouts
                    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                    FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                    MIST (protein-protein) - An integrated Molecular Interaction Database
                    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                    Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.
                    References (79)