l(3)tr, lethal translucida, lincRNA.S4366
Gene model reviewed during 5.45
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ltl using the Feature Mapper tool.
ltl transcripts are expressed in the wing disc in an asymmetric gradient domain, centered on the row of DPP-secreting cells along the AP compartment boundary of the blade primordium.
Transcripts are expressed in ventral cells of the blastoderm embryo. The posterior border coincides with the posterior limit of the ventral furrow. Anteriorly, expression extends up to the anterior pole. The expression is graded with the peak at the anterior end of the embryo. During germ band extension, expression is strong in the head and much weaker in the invaginated mesoderm. In late stages of germ band extension, new expression occurs in the mesoderm in a segmentally repeated pattern. In late embryos, expression is observed in the fat body.
GBrowse - Visual display of RNA-Seq signalsView Dmel\ltl in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: ltl CG32372
Hadorn, 16th Dec. 1940.
The gene is named "larval translucida" based on the translucent, edemic appearance of mutant larvae.