FB2025_01 , released February 20, 2025
Gene: Hsap\H3-3B
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General Information
Symbol
Hsap\H3-3B
Species
H. sapiens
Name
H3.3 histone B
Annotation Symbol
Feature Type
engineered_foreign_gene
FlyBase ID
FBgn0283835
Gene Model Status
Not Applicable
Stock Availability
1 publicly available
Gene Summary
Contribute a Gene Snapshot for this gene.
All Summaries
Also Known As

H3F3B, H3 histone, family 3B

Key Links
Summaries
Alleles, Insertions, Transgenic Constructs
Classical and Insertion Alleles ( 0 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Hsap\H3-3B
Transgenic constructs containing regulatory region of Hsap\H3-3B
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Drosophila melanogaster (Fruit fly) (26)
His3.3A
12 of 14
Yes
Yes
0  
His3:CG33857
7 of 14
No
No
0  
His3:CG33803
6 of 14
No
No
0  
His3:CG33806
6 of 14
No
No
0  
His3:CG33809
6 of 14
No
No
0  
His3:CG33812
6 of 14
No
No
0  
His3:CG33815
6 of 14
No
No
0  
His3:CG33818
6 of 14
No
No
0  
His3:CG33821
6 of 14
No
No
0  
His3:CG33824
6 of 14
No
No
0  
His3:CG33827
6 of 14
No
No
0  
His3:CG33830
6 of 14
No
No
0  
His3:CG33833
6 of 14
No
No
0  
His3:CG33836
6 of 14
No
No
0  
His3:CG33839
6 of 14
No
No
0  
His3:CG33842
6 of 14
No
No
0  
His3:CG33845
6 of 14
No
No
0  
His3:CG33848
6 of 14
No
No
0  
His3:CG33851
6 of 14
No
No
0  
His3:CG33854
6 of 14
No
No
0  
His3:CG33860
6 of 14
No
No
0  
His3:CG33863
6 of 14
No
No
0  
His3:CG33866
6 of 14
No
No
0  
cid
2 of 14
No
No
0  
His3:CG31613
2 of 14
No
No
0  
His3.3B
1 of 14
No
No
0  
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Show/hide secondary interactors 
    (data from AllianceMine provided by esyN)
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    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Other Interaction Browsers
    View in FlyBase Interactions Browser   View in MIST tool (external link)
    Please see the Physical Interaction reports below for full details
    protein-protein
    Physical Interaction
    Assay
    References
    Hsap\H3-3B - trr
    enzymatic study, autoradiography
    (Nan et al., 2019)
    Summary of Genetic Interactions
    esyN Network Diagram
    Other Interaction Browsers
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    Class of Gene
    Stocks and Reagents
    Other Comments
    Relationship to Other Genes
    Source for database merge of
    Additional comments

    Foreign sequence; species == Homo sapiens; gene == H3-3B; HGNC:4765.

    (FlyBase Curators, 1992-)
    Nomenclature History
    Source for database identify of
    Nomenclature comments
    Etymology
    Synonyms and Secondary IDs (10)
    Datasets (0)
    Study focus (0)
    Experimental Role
    Project
    Project Type
    Title
    Study result (0)
    Result
    Result Type
    Title
    External Crossreferences and Linkouts ( 6 )
    Sequence Crossreferences
    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
    Other crossreferences
    Ensembl_Homo_sapiens -
    HUGO Gene Nomenclature Committee -
    MARRVEL - MARRVEL (human gene)
    OMIM_GENE - Online Mendelian Inheritance in Man (Genes)
    OMIM_PHENOTYPE - Online Mendelian Inheritance in Man (Phenotypes)
    References (4)