FlyBase Gene Report: Spyo\Cas9

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Gene: Spyo\Cas9

General Information

Symbol

Spyo\Cas9

Species

S. pyogenes

Name

Cas9 nuclease

Annotation Symbol

Feature Type

engineered_foreign_gene

FlyBase ID

FBgn0284334

Gene Model Status

Stock Availability

200 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

Cas9

Foreign Gene Data

Foreign sequence; species == Streptococcus pyogenes; gene == 'Cas9, Cas9 nuclease'.

(FlyBase Curators, 1992-)

Summaries

Alleles, Insertions, Transgenic Constructs

Classical and Insertion Alleles ( 12 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 153 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Spyo\Cas9

Transgenic constructs containing regulatory region of Spyo\Cas9

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with EcR^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

lethal, with EcR^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

lethal, with EcR^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

lethal, with EcR^gRNA.pCFD3-2, Scer\GAL4^GMR71G10

lethal, with EcR^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

lethal, with EcR^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

lethal, with LpR1^{U6:3.2xgRNA.long}

Spyo\Cas9^Act5C.cPa

lethal, with Ogdh1^gRNA.pCFD3, Scer\GAL4^elav-C155

Spyo\Cas9^UAS.P2

lethal, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^tin.4xCΔ4

lethal, with Rpn8^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

lethal, with Rpn8^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

lethal, with Rpn8^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

lethal, with Rpn8^gRNA.pCFD3-2, Scer\GAL4^GMR71G10

lethal, with Rpn8^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

lethal, with Rpn8^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

lethal | female, with Flacc^TKO.GS00449

Spyo\Cas9^Act5C.cPa

lethal | female, with upd2^TOE.GS00171

Spyo\Cas9^{dxCas9-3.7::VPR.αTub84B}

lethal | male, with Scer\GAL4^elav-C155, Stim^{sgRNA.dual.snRNA:U6:96Ab}

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

lethal - all die before end of larval stage, with pyr^TOE.GS00085

lethal - all die before end of larval stage, with upd1^TOE.GS00169

lethal - all die before end of larval stage, with wg^gRNAx2

lethal - all die before end of P-stage, with hh^TOE.GS00191

lethal - all die before end of P-stage, with pyr^TOE.GS00085

lethal - all die before end of P-stage, with upd1^TOE.GS00169

Spyo\Cas9^{dCas9::VPR.foxo}

lethal - all die before end of P-stage, with upd2^TOE.GS00171

lethal - all die before end of P-stage, with upd3^TOE.GS00129

lethal - all die before end of P-stage, with wg^gRNAx2

lethal - all die during second instar larval stage, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^Act5C.cPa

lethal - all die during second instar larval stage | parental effect, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^αTub84B.PH

partially lethal, with Scer\GAL4^ple.TH-A, Stim^{sgRNA.dual.snRNA:U6:96Ab}

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

partially lethal, with Scer\GAL4^αTub84B.PL, Scer\GAL4^wor.PA, nolo^WKO.3-B3

Spyo\Cas9^nanos.cPa

partially lethal, with sloth1^sgRNA.JAB203

Spyo\Cas9^Act5C.cPa

partially lethal, with sloth2^sgRNA.JAB203

Spyo\Cas9^Act5C.cPa

partially lethal, with upd3^TOE.GS00129

Spyo\Cas9^{dCas9::VPR.wg-ΔC1}

partially lethal | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}, Trpm^U6:3.gRNA1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

partially lethal | maternal effect, with Trpm^U6:3.gRNA1

Spyo\Cas9^nanos.PU

partially lethal - majority die, with Cpr49Ah^UAS.gRNA, Scer\GAL4^phtm.PO

Spyo\Cas9^Act5C.cPa

partially lethal - majority die, with hh^TOE.GS00191

Spyo\Cas9^{dCas9::VPR.αTub84B}

partially lethal - majority die, with LpR1^{U6:3.2xgRNA.short}

Spyo\Cas9^Act5C.cPa

partially lethal - majority die, with Scer\GAL4^elav-C155, Stim^{sgRNA.dual.snRNA:U6:96Ab}

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

partially lethal - majority die, with Scer\GAL4^nSyb.PS, Stim^{sgRNA.dual.snRNA:U6:96Ab}

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

partially lethal - majority die, with Scer\GAL4^phtm.PO, pdm3^UAS.gRNA

Spyo\Cas9^Act5C.cPa

partially lethal - majority die, with Scer\GAL4^ple.PF, Stim^{sgRNA.dual.snRNA:U6:96Ab}

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

partially lethal - majority die | female, with upd1^TOE.GS00169

Spyo\Cas9^{dxCas9-3.7::VPR.αTub84B}

partially lethal - majority live, with Scer\GAL4^elav-C155, nAChRβ1^U6.pCFD4

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

viable, with CG9003^WKO.1-H5, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

viable, with CG34353^WKO.3-A2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

viable, with Dop1R2^WKO.1-C1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

viable, with EcR^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^UAS.P2

viable, with hh^TOE.GS00191

viable, with hid^{U6.gRNAx2.pCFD4}

viable, with Mmp2^WKO.3-C7, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

viable, with Pli^WKO.1-C10, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

viable, with pyr^TOE.GS00085

Spyo\Cas9^{dCas9::VPR.foxo}

viable, with Rpn8^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^UAS.P2

viable, with Scer\GAL4^da.PU, wall^sgRNA.UAS

Spyo\Cas9^UAS.P2

viable, with Scer\GAL4^GMR71G10, danr^WKO.3-B8

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

viable, with Scer\GAL4^GMR71G10, hppy^WKO.1-F10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

viable, with upd3^TOE.GS00129

Spyo\Cas9^{dxCas9-3.7::VPR.αTub84B}

viable, with vn^TOE.GS00144

viable, with wg^gRNAx2

Spyo\Cas9^{dCas9::VPR.wg-ΔC1}

viable | male, with upd1^TOE.GS00169

Spyo\Cas9^{dxCas9-3.7::VPR.αTub84B}

viable | male, with upd2^TOE.GS00171

Spyo\Cas9^{dxCas9-3.7::VPR.αTub84B}

Sterility

Allele

male sterile, with Cyt-c1L^TKO.GS04441

Spyo\Cas9^vas.PU

semi-sterile, with Scer\GAL4^elav-C155, nAChRβ1^U6.pCFD4

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

Other Phenotypes

Allele

abnormal adult locomotory behavior | progressive, with Scer\GAL4^GMR58E02, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

abnormal adult locomotory behavior | progressive, with Scer\GAL4^NP6510, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

abnormal cell migration | oogenesis, with Scer\GAL4^c306, not^WKO.P5-C6

Spyo\Cas9^UAS.P2

abnormal cell migration | oogenesis, with Scer\GAL4^slbo.2.6, not^WKO.P5-C6

Spyo\Cas9^UAS.P2

abnormal cell number, with Scer\GAL4^phtm.PO, Scer\GAL80^spok.1.45, sad^UAS.gRNAx2

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

abnormal cell number, with Scer\GAL4^phtm.PO, Scer\GAL80^spok.1.45, shd^UAS.gRNAx2

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

abnormal cell number | adult stage, with Hsap\RELA^AD.R12G04, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Hsap\RELA^AD.R20G07, Scer\GAL4^DBD.R18H11, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Scer\GAL4^0911-G4, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Scer\GAL4^Clk.1.5, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Scer\GAL4^Clk.-856, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Scer\GAL4^Clk.-856, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Scer\GAL4^Clk.int1-3, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Scer\GAL4^Dvir\Pdf.1.9, Scer\GAL4^GMR78G02, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Scer\GAL4^GMR27G05, bsh^HD_CFD00611

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00451

Spyo\Cas9^UAS.P2

abnormal cell number | adult stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

abnormal cell number | larval stage, with Scer\GAL4^dome-PG14, whd^TKO.GS00854

Spyo\Cas9^UAS.cUa

abnormal cell number | oogenesis, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

abnormal cell number | P-stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

abnormal cell number | spermatogenesis, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Hsap\RELA^AD.R12G04, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Hsap\RELA^AD.R12G04, Scer\GAL4^DBD.R18D09, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Hsap\RELA^AD.R20G07, Scer\GAL4^DBD.R18H11, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Hsap\RELA^AD.R20G07, Scer\GAL4^DBD.R18H11, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Hsap\RELA^AD.R67F03, Scer\GAL4^DBD.R10G01, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Hsap\RELA^AD.R67F03, Scer\GAL4^DBD.R10G01, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^0911-G4, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^0911-G4, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^Clk.1.5, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^Clk.1.5, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^Clk.-856, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^Clk.-856, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^Clk.-856, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^Clk.int1-3, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^Clk.int1-3, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^Dvir\Pdf.1.9, Scer\GAL4^GMR78G02, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | adult stage, with Scer\GAL4^Dvir\Pdf.1.9, Scer\GAL4^GMR78G02, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | conditional, with Scer\GAL4^Mai179, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | conditional, with Scer\GAL4^Mai179, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian behavior | conditional, with Scer\GAL4^P2.4.Pdf, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian rhythm, with Gba1b^TKO.GS00895, Scer\GAL4^GMR56F03, Scer\GAL4^GMR85G01

Spyo\Cas9^UAS.P2

abnormal circadian rhythm, with Gba1b^TKO.GS00895, Scer\GAL4^repo

Spyo\Cas9^UAS.P2

abnormal circadian rhythm | adult stage, with Scer\GAL4^Clk.-856, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian rhythm | adult stage, with Scer\GAL4^Pdf.PU, vri^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian rhythm | adult stage | progressive, with LKRSDH^TOE.GS01508, Scer\GAL4^{LKRSDH-CR70173-TG4.0}

Spyo\Cas9^UAS.cUa

abnormal circadian rhythm | adult stage | progressive, with LKRSDH^TOE.GS01508, Scer\GAL4^nSyb.PP

Spyo\Cas9^UAS.cUa

abnormal circadian rhythm | adult stage | progressive, with LKRSDH^TOE.GS01508, Scer\GAL4^repo.PU

Spyo\Cas9^UAS.cUa

abnormal circadian rhythm | conditional, with Scer\GAL4^Mai179, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian rhythm | conditional, with Scer\GAL4^Mai179, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian rhythm | conditional, with Scer\GAL4^P2.4.Pdf, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian rhythm | conditional, with Scer\GAL4^P2.4.Pdf, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian rhythm | conditional, with Scer\GAL4^tim.PE, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal circadian rhythm | conditional, with Scer\GAL4^tim.PE, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal courtship behavior | clone of cells, with Scer\GAL4^Act5C.PI, fru^HD_CFD02177

Spyo\Cas9^Hsp.geminin

abnormal developmental rate, with Scer\GAL4^elav-C155, Stim^{sgRNA.dual.snRNA:U6:96Ab}

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

abnormal developmental rate, with Scer\GAL4^nSyb.PS, Stim^{sgRNA.dual.snRNA:U6:96Ab}

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

abnormal developmental rate, with Scer\GAL4^ple.PF, Stim^{sgRNA.dual.snRNA:U6:96Ab}

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

abnormal developmental rate | larval stage, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^tin.4xCΔ4

abnormal feeding behavior, with AstC^UAS.KO.pCFD6, Scer\GAL4^pros-V1

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Hsap\RELA^AD.R12G04, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Hsap\RELA^AD.R12G04, Scer\GAL4^DBD.R18D09, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Hsap\RELA^AD.R20G07, Scer\GAL4^DBD.R18H11, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Hsap\RELA^AD.R67F03, Scer\GAL4^DBD.R10G01, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Hsap\RELA^AD.R67F03, Scer\GAL4^DBD.R10G01, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^0911-G4, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^Clk.1.5, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^Clk.-856, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^Clk.-856, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^Clk.-856, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^Clk.-856, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^Clk.int1-3, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^Clk.int1-3, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^Dvir\Pdf.1.9, Scer\GAL4^GMR78G02, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal feeding behavior | adult stage, with Scer\GAL4^Dvir\Pdf.1.9, Scer\GAL4^GMR78G02, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal immune response, with Scer\GAL4^αTub84B.PL, nAChRα6^TOE.GS01969

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

abnormal locomotor behavior, with Pzl^U6.sgRNA, Scer\GAL4^iav.PP

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal locomotor behavior | adult stage, with CapaR^UAS.cKa, CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^Act88F.1.3

Spyo\Cas9^UAS.P2

abnormal locomotor behavior | adult stage, with CapaR^UAS.cKa, CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^how-24B

Spyo\Cas9^UAS.P2

abnormal locomotor behavior | adult stage, with FoxP^UAS.4xgRNA, Scer\GAL4^elav.PU

Spyo\Cas9^UAS.cUa

abnormal locomotor behavior | adult stage, with FoxP^UAS.4xgRNA, Scer\GAL4^futsch-C380

Spyo\Cas9^UAS.cUa

abnormal locomotor behavior | adult stage, with FoxP^UAS.4xgRNA, Scer\GAL4^GMR55G08

Spyo\Cas9^UAS.cUa

abnormal locomotor behavior | adult stage, with FoxP^UAS.4xgRNA, Scer\GAL4^Toll-6-D42

Spyo\Cas9^UAS.cUa

abnormal locomotor behavior | adult stage, with Scer\GAL4^elav-C155, nAChRβ1^U6.pCFD4

abnormal locomotor behavior | adult stage | progressive, with CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^how-24B

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Hsap\RELA^AD.R20G07, Scer\GAL4^DBD.R18H11, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with NKCC^{UAS.4xgRNA.pCFD6}, Scer\GAL4^Clk.-856

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Clk.1.5, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Clk.-856, kcc^{UAS.3xgRNA.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Clk.-856, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Clk.-856, qsm^{UAS.4xgRNA.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Clk.-856, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Clk.-856, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Clk.-856, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Clk.int1-3, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Dvir\Pdf.1.9, Scer\GAL4^GMR78G02, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage, with Scer\GAL4^Dvir\Pdf.1.9, Scer\GAL4^GMR78G02, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage | light conditional, with NKCC^{UAS.4xgRNA.pCFD6}, Scer\GAL4^tim.PE

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage | light conditional, with Scer\GAL4^tim.PE, kcc^{UAS.3xgRNA.pCFD6}

Spyo\Cas9^UAS.P2

abnormal locomotor rhythm | adult stage | light conditional, with Scer\GAL4^tim.PE, qsm^{UAS.4xgRNA.pCFD6}

Spyo\Cas9^UAS.P2

abnormal neuroanatomy | adult stage, with EcR^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^UAS.P2

abnormal neuroanatomy | adult stage, with Eip75B^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Eip75B^gRNA.pCFD3-2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Eip75B^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^GMR56F03, Scer\GAL4^GMR85G01

Spyo\Cas9^UAS.P2

abnormal neuroanatomy | adult stage, with Hsap\RELA^AD.R31C06, Scer\GAL4^DBD.R34G07, bsh^HD_CFD00611

Spyo\Cas9^UAS.P2

abnormal neuroanatomy | adult stage, with peb^U6:3.gRNA

Spyo\Cas9^ey.3x211

abnormal neuroanatomy | adult stage, with Rpn6^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Rpn6^gRNA.pCFD3-2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Rpn6^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Rpn8^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^UAS.P2

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, bsk^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, bsk^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, bsk^gRNA.pCFD3-3

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, plum^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, plum^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, plum^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, plum^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, plum^WKO.1-F11

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, plum^WKO.5-D2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, Uba1^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, Uba1^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, Uba1^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, usp^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, usp^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, usp^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, Uvrag^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, Uvrag^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10, Uvrag^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | adult stage, with Scer\GAL4^Pdf.PU, vri^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

abnormal neuroanatomy | adult stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00451

Spyo\Cas9^UAS.P2

abnormal neuroanatomy | adult stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

abnormal neuroanatomy | adult stage, with Scer\GAL4^wor.PA, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

abnormal neuroanatomy | adult stage | conditional, with axed^U6:3.gRNA

Spyo\Cas9^ey.3x211

abnormal neuroanatomy | larval stage, with Cdc50^sgRNA.U6

Spyo\Cas9^ppk.PS

abnormal neuroanatomy | larval stage, with LpR1^{U6:3.2xgRNA.short}, Scer\GAL4^P2.4.Pdf

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | larval stage, with Nmnat^U6:3.gRNA

abnormal neuroanatomy | larval stage, with peb^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

abnormal neuroanatomy | larval stage, with Sarm^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

abnormal neuroanatomy | larval stage, with Sarm^U6:3.sgRNAx3, Scer\GAL4^tey-5053A

Spyo\Cas9^UAS.P2

abnormal neuroanatomy | larval stage, with Scer\GAL4^αTub84B.PL, Scer\GAL4^wor.PA, nolo^WKO.3-B3

Spyo\Cas9^nanos.cPa

abnormal neuroanatomy | pupal stage, with CG9003^WKO.1-H5, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with CG34353^WKO.3-A2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with Dop1R2^WKO.1-C1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with Mmp2^WKO.3-C7, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with Pli^WKO.1-C10, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with Scer\GAL4^GMR71G10, danr^WKO.3-B8

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with Scer\GAL4^GMR71G10, hppy^WKO.1-F10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with Scer\GAL4^GMR71G10, mamo^gRNA.pCFD3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with Scer\GAL4^GMR71G10, mamo^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with Scer\GAL4^GMR71G10, mamo^WKO.5-A2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neuroanatomy | pupal stage, with Scer\GAL4^GMR71G10, mamo^WKO.5-B2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

abnormal neurophysiology | adult stage, with NKCC^{UAS.4xgRNA.pCFD6}, Scer\GAL4^tim.PE

Spyo\Cas9^UAS.P2

abnormal neurophysiology | adult stage, with Scer\GAL4^tim.PE, kcc^{UAS.3xgRNA.pCFD6}

Spyo\Cas9^UAS.P2

abnormal neurophysiology | adult stage, with Scer\GAL4^tim.PE, qsm^{UAS.4xgRNA.pCFD6}

Spyo\Cas9^UAS.P2

abnormal neurophysiology | adult stage | conditional, with Scer\GAL4^Or47b.7.467, fru^TOE.GS02668

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

abnormal neurophysiology | larval stage, with Syt1^U6.gRNAx3

abnormal planar polarity | adult stage, with Scer\GAL4^nub-AC-62, fz^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

abnormal size | female, with Trpm^{CR7T.U6:3.gRNA2}

Spyo\Cas9^nanos.PU

abnormal size | female, with Trpm^U6:3.gRNA1

Spyo\Cas9^nanos.PU

abnormal size | larval stage, with Scer\GAL4^dome-PG14, whd^TKO.GS00854

Spyo\Cas9^UAS.cUa

abnormal sleep | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^GMR56F03, Scer\GAL4^GMR85G01

Spyo\Cas9^UAS.P2

abnormal sleep | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^GMR85G01

Spyo\Cas9^UAS.P2

abnormal sleep | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^repo

Spyo\Cas9^UAS.P2

abnormal starvation stress response | adult stage, with AstC-R2^UAS.KO.pCFD6, Scer\GAL4^Akh.PL

Spyo\Cas9^UAS.P2

abnormal starvation stress response | adult stage, with CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^Akh.PL

Spyo\Cas9^UAS.P2

abnormal starvation stress response | adult stage | female, with AstC^UAS.KO.pCFD6, Scer\GAL4^pros-V1

Spyo\Cas9^UAS.P2

abnormal stress response, with axed^U6:3.gRNA

Spyo\Cas9^ey.3x211

abnormal stress response | larval stage, with axed^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

abnormal stress response | larval stage, with drpr^U6:3.gRNA

Spyo\Cas9^shot.PJ

abnormal stress response | larval stage, with Sarm^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

abnormal taste perception, with Scer\GAL4^Poxn.13, fuss^{U6:96Ac.4xgRNA.tRNA}

Spyo\Cas9^UAS.P2

abnormal wound healing | adult stage, with Rubicon^TKO.GS04756, Scer\GAL4^repo

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

bang sensitive, with Ogdh1^{R261W.UAS.Tag:FLAG}, Ogdh1^gRNA.pCFD3, Scer\GAL4^elav-C155

Spyo\Cas9^UAS.P2

bang sensitive | progressive, with Ogdh1^{A343V.UAS.Tag:FLAG}, Ogdh1^gRNA.pCFD3, Scer\GAL4^elav-C155

Spyo\Cas9^UAS.P2

bang sensitive | progressive, with Ogdh1^{D507V.UAS.Tag:FLAG}, Ogdh1^gRNA.pCFD3, Scer\GAL4^elav-C155

Spyo\Cas9^UAS.P2

bang sensitive | progressive, with Ogdh1^{P867A.UAS.Tag:FLAG}, Ogdh1^gRNA.pCFD3, Scer\GAL4^elav-C155

Spyo\Cas9^UAS.P2

bang sensitive | progressive, with Ogdh1^{W237C.UAS.Tag:FLAG}, Ogdh1^gRNA.pCFD3, Scer\GAL4^elav-C155

Spyo\Cas9^UAS.P2

chemical resistant | larval stage, with Scer\GAL4^en-e16E, wg^TOE.GS00125

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

decreased body size | larval stage, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^tin.4xCΔ4

decreased body weight | larval stage, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^tin.4xCΔ4

decreased cell death | larval stage | conditional, with Scer\GAL4^en-e16E, wg^TOE.GS00125

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

decreased cell number | adult stage, with Scer\GAL4^wor.PA, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

decreased cell number | embryonic stage 16, with Scer\GAL4^Mef2.247, Scer\GAL4^twi.2PE, Ubx^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

decreased cell number | larval stage, with Scer\GAL4^GMR31H09, Shmt^TKO.GS04720

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

decreased cell number | larval stage, with Scer\GAL4^Pxn.PU, nAChRα6^TKO.GS00614

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

decreased cell number | oogenesis, with Scer\GAL4^{VP16.nanos.UTR}, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

decreased cell number | spermatogenesis, with Scer\GAL4^{VP16.nanos.UTR}, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

decreased efficacy of learning | adult stage, with Scer\GAL4^FoxP-iB-Gal4, aPKC^TKO.GS04189

Spyo\Cas9^UAS.cUa

decreased efficacy of learning | adult stage, with Scer\GAL4^futsch-C380, aPKC^TKO.GS04189

Spyo\Cas9^UAS.cUa

decreased efficacy of learning | adult stage | RU486 conditional, with FoxP^UAS.4xgRNA, Scer\GAL4^GS.nSyb.PB

Spyo\Cas9^UAS.cUa

decreased rate of adult locomotory behavior, with RNaseZ^{F155L.ΔPAM.Tag:V5}

Spyo\Cas9^tin.4xCΔ4

decreased rate of feeding behavior | adult stage, with CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^how-24B

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with FoxP^UAS.4xgRNA, Scer\GAL4^elav.PU

Spyo\Cas9^UAS.cUa

decreased rate of movement | adult stage, with FoxP^UAS.4xgRNA, Scer\GAL4^futsch-C380

Spyo\Cas9^UAS.cUa

decreased rate of movement | adult stage, with FoxP^UAS.4xgRNA, Scer\GAL4^GMR55G08

Spyo\Cas9^UAS.cUa

decreased rate of movement | adult stage, with FoxP^UAS.4xgRNA, Scer\GAL4^Toll-6-D42

Spyo\Cas9^UAS.cUa

decreased rate of movement | adult stage, with Hsap\RELA^AD.R12G04, Scer\GAL4^DBD.R18D09, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with Hsap\RELA^AD.R67F03, Scer\GAL4^DBD.R10G01, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with Scer\GAL4^0911-G4, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with Scer\GAL4^0911-G4, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with Scer\GAL4^Clk.1.5, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with Scer\GAL4^Clk.1.5, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with Scer\GAL4^Clk.-856, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

decreased rate of movement | adult stage, with Scer\GAL4^Dvir\Pdf.1.9, Scer\GAL4^GMR78G02, Scer\GAL80^Pdf.PS, tim^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

decreased size | adult stage, with Hsap\RELA^AD.R31C06, Scer\GAL4^DBD.R34G07, bsh^HD_CFD00611

Spyo\Cas9^UAS.P2

decreased size | adult stage, with Mnat9^{U6.gRNA.pCFD4}, Scer\GAL4^nub-AC-62

Spyo\Cas9^UAS.P2

decreased size | adult stage, with Scer\GAL4^ey-OK107, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

decreased size | adult stage, with Scer\GAL4^hh.PU, wg^{UAS.wg+intergenic-1.pCFD6}

Spyo\Cas9^UAS.P2

decreased size | adult stage, with Scer\GAL4^hh.PU, wg^{UAS.wg+intergenic-2.pCFD6}

Spyo\Cas9^UAS.P2

decreased size | adult stage, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

decreased size | adult stage, with Scer\GAL4^nub-AC-62, wg^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

decreased size | adult stage, with Scer\GAL4^nub-AC-62, wls^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

decreased size | adult stage, with Scer\GAL4^{VP16.nanos.UTR}, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

decreased size | adult stage, with Scer\GAL4^wor.PA, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

decreased size | larval stage, with Nmnat^U6:3.gRNA

decreased size | larval stage, with Noc1^HD_CFD01132, Scer\GAL4^hh.PU

Spyo\Cas9^UAS.uM

decreased sleep | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^GMR56F03, Scer\GAL4^GMR85G01

Spyo\Cas9^UAS.P2

decreased sleep | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^GMR85G01

Spyo\Cas9^UAS.P2

decreased sleep | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^repo

Spyo\Cas9^UAS.P2

flightless, with Flacc^TKO.GS00449

Spyo\Cas9^Act5C.cPa

increased cell death | larval stage, with Scer\GAL4^hh.PU, wg^HMS00794, y^{UAS.gRNA.pCFD6}

Spyo\Cas9^UAS.P2

increased cell death | larval stage, with Scer\GAL4^hh.PU, wg^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

increased cell death | larval stage, with Scer\GAL4^hh.PU, wg^{UAS.wg+intergenic-1.pCFD6}

Spyo\Cas9^UAS.P2

increased cell number | larval stage, with Scer\GAL4^Pxn.PU, nAChRα6^TOE.GS01969

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

increased mortality, with Cpr49Ah^UAS.gRNA, Scer\GAL4^phtm.PO

Spyo\Cas9^Act5C.cPa

increased mortality, with Scer\GAL4^phtm.PO, pdm3^UAS.gRNA

Spyo\Cas9^Act5C.cPa

increased mortality | adult stage, with Scer\GAL4^elav-C155, sgll^TKO.GS01766

Spyo\Cas9^UAS.P2

increased occurrence of cell division | adult stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

increased occurrence of cell division | larval stage, with Scer\GAL4^Pxn.PU, nAChRα6^TOE.GS01969

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

increased occurrence of cell division | P-stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

increased rate of copulation, with Scer\GAL4^elav-C155, spdt^TOE.GS02272

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

increased size | adult stage, with RNaseZ^{F155L.ΔPAM.Tag:V5}

Spyo\Cas9^tin.4xCΔ4

increased size | adult stage, with RNaseZ^{T494I.ΔPAM.Tag:V5}

Spyo\Cas9^tin.4xCΔ4

increased size | adult stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

increased size | larval stage, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^tin.4xCΔ4

increased sleep | adult stage, with AstC^UAS.KO.pCFD6, Scer\GAL4^pros-V1

Spyo\Cas9^UAS.P2

increased sleep | adult stage | nutrition conditional, with AstC-R2^UAS.KO.pCFD6, Scer\GAL4^Akh.PL

Spyo\Cas9^UAS.P2

long lived | adult stage, with CapaR^UAS.cKa, CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^Act88F.1.3

Spyo\Cas9^UAS.P2

majority die during embryonic stage | maternal effect, with Heatr5^{gRNA.U6:3.1+2}

Spyo\Cas9^nanos.cPa

majority die during embryonic stage | maternal effect, with Heatr5^{gRNA.U6:3.3+4}

Spyo\Cas9^nanos.cPa

majority die during embryonic stage | maternal effect, with Trpm^U6:3.gRNA1

Spyo\Cas9^nanos.PU

majority die during larval stage, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^tin.4xCΔ4

radiation resistant | larval stage, with Scer\GAL4^en-e16E, wg^TOE.GS00125

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

segment polarity phenotype, with wg^{gRNA.U6:1-U6:2-U6:3.P1-3}

Spyo\Cas9^Act5C.cPa

segment polarity phenotype, with wls^{gRNA.snRNA:U6:96Ac}

Spyo\Cas9^nanos.cPa

short lived, with CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^CapaR.1.5

Spyo\Cas9^UAS.P2

short lived, with CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^how-24B

Spyo\Cas9^UAS.P2

short lived, with RNaseZ^{F155L.ΔPAM.Tag:V5}

Spyo\Cas9^tin.4xCΔ4

short lived, with RNaseZ^{T494I.ΔPAM.Tag:V5}

Spyo\Cas9^tin.4xCΔ4

short lived, with Scer\GAL4^elav-C155, nAChRβ1^U6.pCFD4

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

short lived, with Scer\GAL4^GMR58E02, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

short lived, with upd3^TOE.GS00129

Spyo\Cas9^{dCas9::VPR.wg-ΔC1}

short lived | calorie restriction conditional, with CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^Akh.PL

Spyo\Cas9^UAS.P2

some die during embryonic stage | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}, Trpm^U6:3.gRNA1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

some die during larval stage, with Cpr49Ah^UAS.gRNA, Scer\GAL4^phtm.PO

Spyo\Cas9^Act5C.cPa

some die during larval stage, with Scer\GAL4^phtm.PO, pdm3^UAS.gRNA

Spyo\Cas9^Act5C.cPa

some die during P-stage, with Cpr49Ah^UAS.gRNA, Scer\GAL4^phtm.PO

Spyo\Cas9^Act5C.cPa

some die during P-stage, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^tin.4xCΔ4

some die during P-stage, with Scer\GAL4^phtm.PO, pdm3^UAS.gRNA

Spyo\Cas9^Act5C.cPa

some die during P-stage, with Scer\GAL4^αTub84B.PL, Scer\GAL4^wor.PA, nolo^WKO.3-B3

Spyo\Cas9^nanos.cPa

visible, with Scer\GAL4^en.PU, wls^{gRNA.snRNA:U6:96Ac}

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

visible | adult stage, with Flacc^TKO.GS00449

Spyo\Cas9^Act5C.cPa

visible | adult stage, with Mnat9^{U6.gRNA.pCFD4}, Scer\GAL4^nub-AC-62

Spyo\Cas9^UAS.P2

visible | adult stage, with Scer\GAL4^CCAP.PP, nAChRβ1^U6.pCFD4

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

visible | adult stage, with Scer\GAL4^elav-C155, nAChRβ1^U6.pCFD4

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

visible | adult stage, with Scer\GAL4^ey-OK107, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

visible | adult stage, with Scer\GAL4^hh.PU, wg^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

visible | adult stage, with Scer\GAL4^hh.PU, wg^{UAS.wg+intergenic-1.pCFD6}

Spyo\Cas9^UAS.P2

visible | adult stage, with Scer\GAL4^hh.PU, wg^{UAS.wg+intergenic-2.pCFD6}

Spyo\Cas9^UAS.P2

visible | adult stage, with Scer\GAL4^mirr-DE, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

visible | adult stage, with Scer\GAL4^nub-AC-62, wg^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

visible | adult stage, with Scer\GAL4^nub-AC-62, wls^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

visible | adult stage, with sloth1^sgRNA.JAB203

Spyo\Cas9^Act5C.cPa

visible | adult stage, with sloth2^sgRNA.JAB203

Spyo\Cas9^Act5C.cPa

visible | adult stage, with upd3^TOE.GS00129

Spyo\Cas9^{dCas9::VPR.wg-ΔC1}

visible | embryonic stage, with Raf^TKO.GS00615, Scer\GAL4^nanos.PU

Spyo\Cas9^UAS.cUa

Phenotype manifest in

Allele

actomyosin contractile ring | embryonic stage 5 | maternal effect, with Graf^TKO.GS00762

Spyo\Cas9^nanos.PR

adult brain, with Gba1b^TKO.GS00895, Scer\GAL4^9-137, Scer\GAL4^GMR83E12

Spyo\Cas9^UAS.P2

adult brain, with Gba1b^TKO.GS00895, Scer\GAL4^GMR56F03, Scer\GAL4^GMR85G01

Spyo\Cas9^UAS.P2

adult brain, with Gba1b^TKO.GS00895, Scer\GAL4^repo

Spyo\Cas9^UAS.P2

adult brain, with Hsap\RELA^AD.R12G04, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

adult brain, with Hsap\RELA^AD.R20G07, Scer\GAL4^DBD.R18H11, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

adult brain, with Hsap\RELA^AD.R65B09, Scer\GAL4^DBD.R18D09, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

adult brain, with Scer\GAL4^0911-G4, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

adult brain, with Scer\GAL4^Clk.1.5, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

adult brain, with Scer\GAL4^Clk.-856, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

adult brain, with Scer\GAL4^Clk.-856, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

adult brain, with Scer\GAL4^Clk.int1-3, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

adult brain, with Scer\GAL4^Dvir\Pdf.1.9, Scer\GAL4^GMR78G02, Scer\GAL80^Pdf.PS, per^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

adult central complex, with Scer\GAL4^pnt-14-94, svp^HD_CFD00451

Spyo\Cas9^UAS.P2

adult central complex, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

adult dopaminergic PAM neuron | adult stage | decreased number, with Scer\GAL4^wor.PA, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

adult fat body, with CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^Akh.PL

Spyo\Cas9^UAS.P2

adult heart, with RNaseZ^{F155L.ΔPAM.Tag:V5}

Spyo\Cas9^tin.4xCΔ4

adult heart, with RNaseZ^{T494I.ΔPAM.Tag:V5}

Spyo\Cas9^tin.4xCΔ4

adult heart ventral longitudinal muscle cell | P-stage, with Scer\GAL4^org-1.HN39, twi^UAS.gRNAx4

Spyo\Cas9^UAS.P2

adult marginal nerve wrapping glial cell, with Rubicon^TKO.GS04756, Scer\GAL4^repo

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

adult mushroom body, with Scer\GAL4^ey-OK107, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

adult mushroom body, with Scer\GAL4^wor.PA, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

adult olfactory receptor neuron Or22, with peb^U6:3.gRNA

Spyo\Cas9^ey.3x211

adult olfactory receptor neuron Or22 | conditional, with axed^U6:3.gRNA

Spyo\Cas9^ey.3x211

adult olfactory receptor neuron Or47b | adult stage | conditional, with Scer\GAL4^Or47b.7.467, fru^TOE.GS02668

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

adult protocerebral bridge 1 glomerulus-ellipsoid body tile-nodulus 1 neuron | adult stage | ectopic, with Scer\GAL4^pnt-14-94, svp^HD_CFD00451

Spyo\Cas9^UAS.P2

adult protocerebral bridge 1 glomerulus-ellipsoid body tile-nodulus 1 neuron | adult stage | ectopic, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

adult protocerebral bridge 1 glomerulus-fan-shaped body-nodulus neuron | adult stage | decreased number, with Scer\GAL4^pnt-14-94, svp^HD_CFD00451

Spyo\Cas9^UAS.P2

adult protocerebral bridge 1 glomerulus-fan-shaped body-nodulus neuron | adult stage | decreased number, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

adult s-LNv neuron, with Scer\GAL4^Pdf.PU, vri^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

adult s-LNv neuron | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^GMR56F03, Scer\GAL4^GMR85G01

Spyo\Cas9^UAS.P2

axon | adult stage, with EcR^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^UAS.P2

axon | adult stage, with Eip75B^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Eip75B^gRNA.pCFD3-2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Eip75B^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with peb^U6:3.gRNA

Spyo\Cas9^ey.3x211

axon | adult stage, with Rpn6^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Rpn6^gRNA.pCFD3-2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Rpn6^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Rpn8^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^UAS.P2

axon | adult stage, with Scer\GAL4^GMR71G10, bsk^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, bsk^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, bsk^gRNA.pCFD3-3

axon | adult stage, with Scer\GAL4^GMR71G10, plum^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, plum^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, plum^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, plum^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, plum^WKO.1-F11

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, plum^WKO.5-D2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, Uba1^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, Uba1^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, Uba1^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, usp^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, usp^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, usp^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, Uvrag^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, Uvrag^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage, with Scer\GAL4^GMR71G10, Uvrag^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | adult stage | conditional, with axed^U6:3.gRNA

Spyo\Cas9^ey.3x211

axon | larval stage, with axed^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

axon | pupal stage, with CG9003^WKO.1-H5, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with CG34353^WKO.3-A2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with Dop1R2^WKO.1-C1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with Mmp2^WKO.3-C7, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with Pli^WKO.1-C10, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with Scer\GAL4^GMR71G10, danr^WKO.3-B8

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with Scer\GAL4^GMR71G10, hppy^WKO.1-F10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with Scer\GAL4^GMR71G10, mamo^gRNA.pCFD3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with Scer\GAL4^GMR71G10, mamo^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with Scer\GAL4^GMR71G10, mamo^WKO.5-A2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon | pupal stage, with Scer\GAL4^GMR71G10, mamo^WKO.5-B2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

axon terminus | adult stage | somatic clone, with loaf^{gRNA.snRNA:U6:96Aa.snRNA:U6:96Ac}

Spyo\Cas9^UAS.P2

border follicle cell, with Scer\GAL4^c306, not^WKO.P5-C6

Spyo\Cas9^UAS.P2

border follicle cell, with Scer\GAL4^slbo.2.6, not^WKO.P5-C6

Spyo\Cas9^UAS.P2

cortical zone of lymph gland primary lobe | larval stage, with Scer\GAL4^dome-PG14, whd^TKO.GS00854

Spyo\Cas9^UAS.cUa

dendrite | larval stage, with axed^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

dendrite | larval stage, with Cdc50^sgRNA.U6

Spyo\Cas9^ppk.PS

dendrite | larval stage, with drpr^U6:3.gRNA

Spyo\Cas9^shot.PJ

dendrite | larval stage, with LpR1^{U6:3.2xgRNA.short}, Scer\GAL4^P2.4.Pdf

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

dendrite | larval stage, with Nmnat^U6:3.gRNA

dendrite | larval stage, with peb^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

dendrite | larval stage, with Sarm^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

distal axon | larval stage, with Sarm^U6:3.sgRNAx3, Scer\GAL4^tey-5053A

Spyo\Cas9^UAS.P2

egg, with Scer\GAL4^{VP16.mat.αTub67C}, Trpm^U6:3.gRNA1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

egg, with Trpm^U6:3.gRNA1

Spyo\Cas9^nanos.PU

egg chamber, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

ellipsoid body, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

embryo | maternal effect, with Src42A^gRNA.pCFD3

Spyo\Cas9^nanos.cPa

embryonic/first instar larval cuticle | embryonic stage, with Raf^TKO.GS00615, Scer\GAL4^nanos.PU

Spyo\Cas9^UAS.cUa

embryonic/larval heart | larval stage, with RNaseZ^U6.3xsgRNA

Spyo\Cas9^tin.4xCΔ4

embryonic/larval hemocyte | decreased number | larval stage, with Scer\GAL4^Pxn.PU, nAChRα6^TKO.GS00614

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

embryonic/larval hemocyte | increased number | larval stage, with Scer\GAL4^Pxn.PU, nAChRα6^TOE.GS01969

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

embryonic/larval hypodermal muscle cell | decreased number | embryonic stage 16, with Scer\GAL4^Mef2.247, Scer\GAL4^twi.2PE, Ubx^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

embryonic/larval hypodermal muscle cell | embryonic stage 16, with Scer\GAL4^Mef2.247, Scer\GAL4^twi.2PE, Ubx^{UAS.gRNAx4.pCFD6}

Spyo\Cas9^UAS.P2

embryonic/larval motor neuron | larval stage, with Sarm^U6:3.sgRNAx3, Scer\GAL4^tey-5053A

Spyo\Cas9^UAS.P2

embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4^αTub84B.PL, Scer\GAL4^wor.PA, nolo^WKO.3-B3

Spyo\Cas9^nanos.cPa

embryonic/larval optic lobe | larval stage, with Scer\GAL4^GMR31H09, Shmt^TKO.GS04720

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

enteroendocrine cell | decreased number, with Scer\GAL4^phtm.PO, Scer\GAL80^spok.1.45, sad^UAS.gRNAx2

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

enteroendocrine cell | decreased number, with Scer\GAL4^phtm.PO, Scer\GAL80^spok.1.45, shd^UAS.gRNAx2

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

extracellular vesicle | decreased number | larval stage, with shrb^U6.gRNAx2

extracellular vesicle | decreased number | larval stage, with TSG101^U6.gRNAx2

eye, with Scer\GAL4^ey-OK107, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

eye, with Scer\GAL4^mirr-DE, mbt^HD_CFD00807

Spyo\Cas9^UAS.uM

fan-shaped body, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

female germline cell | absent | adult stage, with Scer\GAL4^{VP16.nanos.UTR}, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

female germline cell | adult stage | increased number, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

gamma Kenyon cell | adult stage, with EcR^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^UAS.P2

gamma Kenyon cell | adult stage, with Eip75B^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Eip75B^gRNA.pCFD3-2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Eip75B^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Rpn6^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Rpn6^gRNA.pCFD3-2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Rpn6^gRNA.pCFD3-3, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Rpn8^gRNA.pCFD3-1, Scer\GAL4^GMR71G10

Spyo\Cas9^UAS.P2

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, bsk^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, bsk^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, bsk^gRNA.pCFD3-3

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, plum^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, plum^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, plum^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, plum^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, plum^WKO.1-F11

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, plum^WKO.5-D2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, Uba1^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, Uba1^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, Uba1^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, usp^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, usp^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, usp^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, Uvrag^gRNA.pCFD3-1

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, Uvrag^gRNA.pCFD3-2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10, Uvrag^gRNA.pCFD3-3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with CG9003^WKO.1-H5, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with CG34353^WKO.3-A2, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with Dop1R2^WKO.1-C1, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with Mmp2^WKO.3-C7, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with Pli^WKO.1-C10, Scer\GAL4^GMR71G10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with Scer\GAL4^GMR71G10, danr^WKO.3-B8

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with Scer\GAL4^GMR71G10, hppy^WKO.1-F10

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with Scer\GAL4^GMR71G10, mamo^gRNA.pCFD3

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with Scer\GAL4^GMR71G10, mamo^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with Scer\GAL4^GMR71G10, mamo^WKO.5-A2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

gamma Kenyon cell | pupal stage, with Scer\GAL4^GMR71G10, mamo^WKO.5-B2

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

germinal proliferation center hub, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

germinal proliferation center hub, with Scer\GAL4^{VP16.nanos.UTR}, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

Golgi apparatus | embryonic stage, with Heatr5^{gRNA.U6:3.1+2}

Spyo\Cas9^nanos.cPa

hypodermal muscle of A1-7 | larval stage, with Syt1^U6.gRNAx3

indirect flight muscle | adult stage, with Dld^TKO.GS00548, Scer\GAL4^Act88F.PB

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

indirect flight muscle | adult stage, with Dlst^TKO.GS03432, Scer\GAL4^Act88F.PB

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

indirect flight muscle | adult stage, with Ogdh1^TKO.GS00550, Scer\GAL4^Act88F.PB

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

intracellular vesicle | larval stage, with shrb^U6.gRNAx2

intracellular vesicle | larval stage, with TSG101^U6.gRNAx2

lamina | absent | larval stage, with Scer\GAL4^GMR31H09, Shmt^TKO.GS04720

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

lamina monopolar neuron | adult stage, with Scer\GAL4^GMR27G05, bsh^HD_CFD00611

Spyo\Cas9^UAS.P2

lamina monopolar neuron L4 | adult stage, with Hsap\RELA^AD.R31C06, Scer\GAL4^DBD.R34G07, bsh^HD_CFD00611

Spyo\Cas9^UAS.P2

larval brain | larval stage, with LpR1^{U6:3.2xgRNA.short}, Scer\GAL4^P2.4.Pdf

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

larval dorsal multidendritic neuron ddaC, with axed^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

larval dorsal multidendritic neuron ddaC, with drpr^U6:3.gRNA

Spyo\Cas9^shot.PJ

larval dorsal multidendritic neuron ddaC, with Nmnat^U6:3.gRNA

larval dorsal multidendritic neuron ddaC, with peb^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

larval dorsal multidendritic neuron ddaC, with Sarm^U6:3.gRNA

Spyo\Cas9^SOP.scE1x8

larval dorsal multidendritic neuron ddaC | larval stage, with Cdc50^sgRNA.U6

Spyo\Cas9^ppk.PS

larval dorsal multidendritic neuron ddaE, with drpr^U6:3.gRNA

Spyo\Cas9^shot.PJ

larval multidendritic class IV neuron | larval stage, with ATP8A^sgRNA.U6

Spyo\Cas9^ppk.PS

larval multidendritic class IV neuron | larval stage, with Cdc50^sgRNA.U6

Spyo\Cas9^ppk.PS

lipid droplet | adult stage, with CapaR^{UAS.gRNAx4.pCFD6}, Scer\GAL4^Akh.PL

Spyo\Cas9^UAS.P2

lipid droplet | adult stage | clone of cells | increased number, with Scer\GAL4^Act5C.PI, fru^HD_CFD02177

Spyo\Cas9^Hsp.geminin

LNv neuron | larval stage, with LpR1^{U6:3.2xgRNA.short}, Scer\GAL4^P2.4.Pdf

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

lysosome | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^9-137, Scer\GAL4^GMR83E12

Spyo\Cas9^UAS.P2

lysosome | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^GMR56F03, Scer\GAL4^GMR85G01

Spyo\Cas9^UAS.P2

lysosome | adult stage, with Gba1b^TKO.GS00895, Scer\GAL4^repo

Spyo\Cas9^UAS.P2

male germline cell | absent | adult stage, with Scer\GAL4^{VP16.nanos.UTR}, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

male germline cell | adult stage | increased number, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

marginal nerve, with Rubicon^TKO.GS04756, Scer\GAL4^repo

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

medulla | larval stage, with Scer\GAL4^GMR31H09, Shmt^TKO.GS04720

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

myofibril | adult stage, with Dld^TKO.GS00548, Scer\GAL4^Act88F.PB

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

myofibril | adult stage, with Dlst^TKO.GS03432, Scer\GAL4^Act88F.PB

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

myofibril | adult stage, with Ogdh1^TKO.GS00550, Scer\GAL4^Act88F.PB

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

nephrocyte, with Scer\GAL4^Ugt36A1.PK, Tbc1d8-9^2xsgRNA.U6

Spyo\Cas9^UAS.P2

nephrocyte, with Scer\GAL4^Ugt36A1.PK, Tbc1d8-9^U6.gRNA.B

Spyo\Cas9^UAS.P2

neuron projection | adult stage, with Scer\GAL4^Pdf.PU, vri^{UAS.gRNAx3.pCFD6}

Spyo\Cas9^UAS.P2

neuron projection | adult stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00451

Spyo\Cas9^UAS.P2

neuron projection | adult stage, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

NMJ bouton | decreased number | larval stage, with Scer\GAL4^αTub84B.PL, Scer\GAL4^wor.PA, nolo^WKO.3-B3

Spyo\Cas9^nanos.cPa

NMJ bouton | decreased number | larval stage, with Syx5^U6:3.gRNA.GQ

NMJ bouton | increased number | larval stage, with shrb^U6.gRNAx2

NMJ bouton | increased number | larval stage, with TSG101^U6.gRNAx2

nodulus, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

oocyte | absent, with Scer\GAL4^{VP16.nanos.UTR}, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

optic lobe neuroepithelial cell | decreased number | larval stage, with Scer\GAL4^GMR31H09, Shmt^TKO.GS04720

Spyo\Cas9^{UAS.Tag:NLS(Ude)}

outer medulla | adult stage | somatic clone, with loaf^{gRNA.snRNA:U6:96Aa.snRNA:U6:96Ac}

Spyo\Cas9^UAS.P2

ovary, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

ovary, with Scer\GAL4^{VP16.nanos.UTR}, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

ovary, with Trpm^{CR7T.U6:3.gRNA2}

Spyo\Cas9^nanos.PU

ovary, with Trpm^U6:3.gRNA1

Spyo\Cas9^nanos.PU

photoreceptor cell R7 | adult stage | somatic clone, with loaf^{gRNA.snRNA:U6:96Aa.snRNA:U6:96Ac}

Spyo\Cas9^UAS.P2

primary dendrite | adult stage, with Hsap\RELA^AD.R31C06, Scer\GAL4^DBD.R34G07, bsh^HD_CFD00611

Spyo\Cas9^UAS.P2

protocerebral bridge, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

sarcomere | adult stage, with Dld^TKO.GS00548, Scer\GAL4^Act88F.PB

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

sarcomere | adult stage, with Dlst^TKO.GS03432, Scer\GAL4^Act88F.PB

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

scutellar bristle, with sloth1^sgRNA.JAB203

Spyo\Cas9^Act5C.cPa

scutellar bristle, with sloth2^sgRNA.JAB203

Spyo\Cas9^Act5C.cPa

slit diaphragm, with Scer\GAL4^Ugt36A1.PK, Tbc1d8-9^2xsgRNA.U6

Spyo\Cas9^UAS.P2

slit diaphragm, with Scer\GAL4^Ugt36A1.PK, Tbc1d8-9^U6.gRNA.B

Spyo\Cas9^UAS.P2

spermatid, with Cyt-c1L^TKO.GS04441

Spyo\Cas9^vas.PU

spermatocyte | decreased number, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

spermatogonium | increased number, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

spermatozoon | absent, with Cyt-c1L^TKO.GS04441

Spyo\Cas9^vas.PU

synapse | adult stage | decreased number, with Hsap\RELA^AD.R31C06, Scer\GAL4^DBD.R34G07, bsh^HD_CFD00611

Spyo\Cas9^UAS.P2

testis, with Scer\GAL4^NP1624, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

testis, with Scer\GAL4^{VP16.nanos.UTR}, mRpL50^{U6.gRNA.pCFD4}

Spyo\Cas9^UAS.P2

type Ib terminal bouton | larval stage, with shrb^U6.gRNAx2

Spyo\Cas9^wor.PC

type II neuroblast | adult stage | increased number, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

type II neuroblast | P-stage | increased number, with Scer\GAL4^pnt-14-94, svp^HD_CFD00600

Spyo\Cas9^UAS.P2

ventral denticle belt | absent | embryonic stage, with Raf^TKO.GS00615, Scer\GAL4^nanos.PU

Spyo\Cas9^UAS.cUa

ventral denticle belt | embryonic stage, with Heatr5^{gRNA.U6:3.1+2}

Spyo\Cas9^nanos.cPa

wing, with Flacc^TKO.GS00449

Spyo\Cas9^Act5C.cPa

wing, with Mnat9^{U6.gRNA.pCFD4}, Scer\GAL4^nub-AC-62

Spyo\Cas9^UAS.P2

wing, with Scer\GAL4^CCAP.PP, nAChRβ1^U6.pCFD4

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

wing, with Scer\GAL4^elav-C155, nAChRβ1^U6.pCFD4

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

wing, with Scer\GAL4^en.PU, wls^{gRNA.snRNA:U6:96Ac}

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

wing, with Scer\GAL4^hh.PU, wg^{UAS.wg+intergenic-1.pCFD6}

Spyo\Cas9^UAS.P2

wing, with Scer\GAL4^hh.PU, wg^{UAS.wg+intergenic-2.pCFD6}

Spyo\Cas9^UAS.P2

wing, with Scer\GAL4^nub-AC-62, fz^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

wing, with Scer\GAL4^nub-AC-62, wg^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

wing, with Scer\GAL4^nub-AC-62, wls^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

wing disc | larval stage, with Noc1^HD_CFD01132, Scer\GAL4^hh.PU

Spyo\Cas9^UAS.uM

wing disc | third instar larval stage, with Scer\GAL4^dpp.PU, wg^TOE.GS00125

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

wing disc posterior compartment | larval stage, with Scer\GAL4^hh.PU, wg^HMS00794, y^{UAS.gRNA.pCFD6}

Spyo\Cas9^UAS.P2

wing disc posterior compartment | larval stage, with Scer\GAL4^hh.PU, wg^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

wing disc posterior compartment | larval stage, with Scer\GAL4^hh.PU, wg^{UAS.wg+intergenic-1.pCFD6}

Spyo\Cas9^UAS.P2

wing disc posterior compartment | larval stage | conditional, with Scer\GAL4^en-e16E, wg^TOE.GS00125

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

wing margin, with Scer\GAL4^hh.PU, wg^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

wing margin, with Scer\GAL4^nub-AC-62, wg^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

wing margin, with Scer\GAL4^nub-AC-62, wls^{UAS.gRNAx2.pCFD6}

Spyo\Cas9^UAS.P2

wing pouch | ectopic | third instar larval stage, with Scer\GAL4^dpp.PU, wg^TOE.GS00125

Spyo\Cas9^{dCas9::VPR.UAS.Tag:FLAG}

Z disc | adult stage, with Ogdh1^TKO.GS00550, Scer\GAL4^Act88F.PB

Spyo\Cas9^{UAS.Tag:NLS(Unk)}

Orthologs

Downloads

Download All DIOPT Orthologs

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 2 )

Allele

Disease

Evidence

References

Spyo\Cas9^UAS.P2

model of intestinal cancer

CEC with N^HD_CFD01184

(Bahuguna et al., 2021)

CEC with Mad^HD_CFD00651

(Bahuguna et al., 2021)

Spyo\Cas9^UAS.uM.-FRT

model of intestinal cancer

CEC with neur^HD_CFD01179

(Bahuguna et al., 2021)

CEC with N^HD_CFD01184

(Bahuguna et al., 2021)

CEC with Mad^HD_CFD00651

(Bahuguna et al., 2021)

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Other Interaction Browsers

Summary of Genetic Interactions

esyN Network Diagram

Other Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Class of Gene

engineered_foreign_gene

(FlyBase Curators, 1992-)

Stocks and Reagents

Stocks (200)

66554

y¹ M{vas-Cas9}ZH-2A

92760

w^* P{repo-Cas9.K}5D

90971

w^*; P{UAS-PE2}attP40

81927

P{R28E04-Cas9.P}5A, w^*

81930

w^*; P{Tub-Cas9.H}M13-1

54595

w¹¹¹⁸; P{UAS-Cas9.C}attP2

91792

w^*; P{bnk-dCas9::VPR}attP40

93004

w^*; P{nanos-gin.Cas9}attP40

51324

w¹¹¹⁸; PBac{vas-Cas9}VK00027

54596

w¹¹¹⁸; P{UAS-Cas9.D10A}attP2

77470

w¹¹¹⁸; PBac{CATCHA.1}VK00027

92793

w^*; P{Hsp-Cas9.T2A.GFP}attP2

More stocks available...

Other Comments

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Cas9

(González Morales et al., 2023, Trivedi et al., 2020, Pathak et al., 2017, Lin et al., 2015, Port and Bullock, 2015.1.13, Sebo et al., 2014, Gratz et al., 2013, Kondo and Ueda, 2013, Kondo and Ueda, 2013, Ren et al., 2013, Yu et al., 2013)

Spyo\Cas9

Zzzz\Cas9

Name Synonyms

Cas9 nuclease

Secondary FlyBase IDs

FBgn0284169
FBgn0266461

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 0 )

References (247)