BEST:CK02318 , LKR, lys, lysine
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\LKRSDH using the Feature Mapper tool.
The expression of this gene along with several others is induced in salivary glands in pupae at the time of head eversion. This stage is characterized by an increase in the ecdysone titer as well as large amounts of cell death in this tissue.
GBrowse - Visual display of RNA-Seq signalsView Dmel\LKRSDH in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Renamed from 'LKR' to 'LKRSDH' to minimise confusion with the 'Lkr' ('Leucokinin receptor') gene symbol, from which it differed only by case. Moreover, 'LKRSDH' better reflects the symbol used in the original paper ('dLKR/SDH') which initially characterised the gene (FBrf0205793).
Source for merge of CG7144 anon-WO0149856.1 was sequence comparison ( date:051113 ).
LKR regulates hormone-mediated histone arginine methylation and transcription of cell death genes.
Identification: cDNA screen for secreted and transmembrane proteins expressed during embryogenesis.
E. H. Grell, 1957.