l(1)G0255, l(1)G0290, lethal (1) G0255, Fum
Gene model reviewed during 5.52
Low-frequency RNA-Seq exon junction(s) not annotated.
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Fum1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Fum1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Fum1 l(1)G0255
The effect of dietary sucrose and ethanol on Fum activity in the third larval instar has been studied.
The structural gene for fumarase (FUM; L-malate hydro-lyase). Enzyme level observed depends on genetic background (Laurie-Ahlberg, Maroni, Bewley, Lucchesi and Wier, 1980). Enzyme levels higher in females than in males in midlarval, pupal and pharate-adult stages; female levels drop and are surpassed by male levels in older adults (Whitney and Lucchesi, 1972). Head and thorax have higher activities than abdomen (Pipkin, Chakrabarthy and Bremner, 1977). Activity equally distributed between mitochondrial and cytoplasmic fractions (Pipkin et al., 1977).