gfat, zep, zeppelin
Please see the JBrowse view of Dmel\Gfat1 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.47
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Gfat1 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: cyclical, peak ZT21-0
Comment: along where chitinous masticatory organs are synthesized
Expressed cyclically in the adult fat body.
Gfat1 transcript is expressed in cuticle-forming tissues.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Gfat1 in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
New annotation (CG40197) in release 3 of the genome annotation.
zep is required for normal epidermal development in the embryo.
Mutations in zep partially suppress the cuticular defects associated with shg mutations. Mutations in zep result in embryonic lethality; homozygous embryos secrete cuticles that show subtle epidermal patterning defects but a very dramatic increase in size relative to their wild-type siblings. This size difference does not appear to result from increased cell number or increased cell size, but rather may reflect a greater elasticity of either the epidermal layer or the cuticle itself.
Source for merge of: Gfat1 CG40197
Source for merge of: Gfat1 zep
Source for merge of Gfat1 CG40197 was sequence comparison ( date:030301 ).
Named for the extreme ballooning of the embryos when squashed under coverslips in the course of doing cuticle preparations.
