FlyBase Gene Report: Dmel\Camta

General Information

Symbol

Dmel\Camta

Species

D. melanogaster

Name

Calmodulin-binding transcription activator

Annotation Symbol

CG42332

Feature Type

protein_coding_gene

FlyBase ID

FBgn0287478

Gene Model Status

Current

Stock Availability

61 publicly available

Gene Summary

Calmodulin-binding transcription activator (Camta) encodes a Ca[2+]-responsive transcription factor that either binds directly to DNA sequences containing a CGCG core motif or functions as a coactivator of NKX2 transcription factors. It mediates various physiological functions, including the regulation of visual signal transduction, memory formation and cell survival. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

dCAMTA, croaker, cro, Calmodulin-binding transcription factor, DmCAMTA

Key Links

Genomic Location

Cytogenetic map

45D8-45E1

Sequence location

2R:9,446,046..9,480,076 [+]

Recombination map

2-60

RefSeq locus

NT_033778 REGION:9446046..9480076

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (12 terms)

Molecular Function (6 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

enables calmodulin binding

inferred from direct assay

(Bouche et al., 2002)

enables DNA-binding transcription activator activity, RNA polymerase II-specific

inferred from direct assay

(Gong et al., 2007, Bouche et al., 2002)

inferred from mutant phenotype

(Han et al., 2006)

enables transcription cis-regulatory region binding

inferred from direct assay

(Gong et al., 2007, Bouche et al., 2002)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables DNA binding

inferred from electronic annotation with InterPro:IPR005559

(InterPro Project Members, 2004-)

enables double-stranded DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN000596526

(GO Reference Genome Project, 2011-)

enables transcription coregulator activity

inferred from biological aspect of ancestor with PANTHER:PTN000596526

(GO Reference Genome Project, 2011-)

Biological Process (5 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

involved_in cellular response to calcium ion

inferred from genetic interaction with FLYBASE:Cam; FB:FBgn0000253

(Han et al., 2006)

involved_in negative regulation of opsin-mediated signaling pathway

inferred from mutant phenotype

(Bouche et al., 2002)

involved_in positive regulation of transcription by RNA polymerase II

inferred from direct assay

(Gong et al., 2007, Bouche et al., 2002)

involved_in response to light stimulus

inferred from mutant phenotype

(Gong et al., 2007)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in regulation of transcription by RNA polymerase II

inferred from biological aspect of ancestor with PANTHER:PTN000596526

(GO Reference Genome Project, 2011-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

is_active_in nucleus

inferred from direct assay

(Han et al., 2006)

located_in nucleus

inferred from direct assay

(Gong et al., 2007, Bouche et al., 2002)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000596526

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

UNCLASSIFIED DNA BINDING DOMAIN TRANSCRIPTION FACTORS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Gene Group (FlyBase)

UNCLASSIFIED DNA BINDING DOMAIN TRANSCRIPTION FACTORS -: This group comprises DNA-binding transcription factors that do not classify under other domain-based transcription factor groups in FlyBase.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Camta for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry B7YZU4)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Multiphase exon postulated: exon reading frame differs in alternative transcripts; overlap >20aa.

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.49

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Camta-RB

FBtr0299845

NM_001144153

6877

2005

Camta-RD

FBtr0299846

NM_136647

6273

1881

Camta-RE

FBtr0299847

NM_001144154

6156

1842

Camta-RF

FBtr0300527

NM_001144152

6994

2044

Camta-RG

FBtr0301766

NM_001169627

6874

2004

Camta-RH

FBtr0339381

NM_001299320

7588

1675

Camta-RI

FBtr0339382

NM_001299321

6902

1988

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Camta-PB

FBpp0289123

219.8

2005

7.58

FBpp0289124

208.0

1881

6.86

FBpp0289125

204.1

1842

7.04

FBpp0289754

223.6

2044

7.14

FBpp0290980

219.7

2004

7.58

FBpp0308472

185.8

1675

6.38

FBpp0308473

217.2

1988

7.83

A0A0B4LF15

NP_001286250

AHN56048

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Camta using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.74

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic brain

(Fisher et al., 2012)

embryonic Malpighian tubule

(Fisher et al., 2012)

embryonic proventriculus

(Fisher et al., 2012)

embryonic/larval midgut

(Fisher et al., 2012)

organism | faint | ubiquitous

(Fisher et al., 2012)

larval ventral nerve cord

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

is_active_in nucleus

inferred from direct assay

(Han et al., 2006)

located_in nucleus

inferred from direct assay

(Gong et al., 2007, Bouche et al., 2002)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Camta in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Camta

View exonic expression by tissue for Dmel\Camta

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35974/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0287478

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0259234

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0287478

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 16 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 25 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Camta

Transgenic constructs containing regulatory region of Camta

Aberrations (Deficiencies and Duplications) ( 8 )

Inferred from experimentation ( 8 )

Gene disrupted in

Df(2R)11

(Georgiev et al., 2012)

Df(2R)BSC408

(Sato et al., 2019)

Df(2R)ED1791

(Sato et al., 2019)

Df(2R)Np5

(Sato et al., 2019)

Df(2R)w45-19g

(Han et al., 2006)

Df(2R)w45-30n

(Sato et al., 2019)

Gene not disrupted in

Df(2R)Np5

(Georgiev et al., 2012)

Df(2R)w73-1

(Georgiev et al., 2012, Han et al., 2006)

Df(2R)w73-2

(Sato et al., 2019)

Inferred from location ( 5 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | recessive

Camta^{MI04570-TG4.1}

lethal - all die before end of pupal stage, with Scer\GAL4^pnr-MD237

Camta^GD14755

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Camta^GD14756

viable, with Scer\GAL4^Mef2.PR

Camta^GD14756

viable, with Scer\GAL4^pnr-MD237

Camta^GD14756

viable, with Scer\GAL4^tin.CΔ4

Camta^GD14756

Sterility

Allele

fertile

Camta^f05489

Other Phenotypes

Allele

abnormal courtship behavior | female

Camta^cro

abnormal courtship behavior | male

Camta^cro

abnormal flight | male

Camta^cro

abnormal learning | adult stage

Camta^12.132

abnormal neurophysiology

abnormal song, with Scer\GAL4^{Camta-MI04570-TG4.1}

Camta^GLV21048

abnormal song, with Scer\GAL4^elav-C155

Camta^GLV21048

abnormal song, with Scer\GAL4^fru.PU

Camta^GLV21048

abnormal song, with Scer\GAL4^nSyb.PU

Camta^GLV21048

abnormal song (with Camta^cro)

abnormal song (with Camta^MI01580)

Camta^cro

abnormal song (with Camta^MI04570)

Camta^cro

abnormal song (with Camta^{MI04570-TG4.1})

Camta^cro

abnormal song | recessive

Camta^cro

abnormal song | somatic clone, with Scer\FLP1^{FLPo.oc.Tag:NLS(SV40-largeT)}, Scer\GAL4^fru.PU

Camta^GLV21048

abnormal song | somatic clone, with Scer\FLP1^fru, Scer\GAL4^p52a

Camta^GLV21048

some die during pupal stage, with Scer\GAL4^pnr-MD237

Camta^GD14755

visible, with Scer\GAL4^pnr-MD237

Camta^GD14756

Phenotype manifest in

Allele

eye photoreceptor cell

trichogen cell, with Scer\GAL4^pnr-MD237

Camta^GD14756

trichogen cell | increased number, with Scer\GAL4^pnr-MD237

Camta^GD14756

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (7)

Hsap\CAMTA2

11 of 14

Yes

Hsap\CAMTA1

10 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (6)

Rnor\Camta2

11 of 14

Yes

Rnor\Camta1

10 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (6)

Mmus\Camta2

11 of 14

Yes

Mmus\Camta1

10 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (3)

Xtro\camta1

8 of 13

Yes

Xtro\camta2

7 of 13

Yes

Xtro\vn2r1p

1 of 13

Yes

Danio rerio (Zebrafish) (7)

Drer\camta1b

11 of 14

Yes

Drer\camta1a

8 of 14

Yes

Drer\LOC100334756

4 of 14

Yes

Drer\camta2

3 of 14

Yes

Drer\aspm

1 of 14

Drer\LOC110439124

1 of 14

Yes

Drer\myo5b

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (3)

Cele\camt-1

10 of 14

Yes

Cele\cutl-18

1 of 14

Cele\hum-7

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (2)

Agam\AgaP_AGAP007133

10 of 12

Yes

Agam\AgaP_AGAP003703

1 of 12

Arabidopsis thaliana (thale-cress) (11)

Atha\AT1G67310

7 of 13

Yes

Atha\AT3G16940

7 of 13

Yes

Atha\AT4G16150

7 of 13

Yes

Atha\AT5G64220

7 of 13

Yes

Atha\EICBP.B

7 of 13

Yes

Atha\SR1

7 of 13

Yes

Atha\AT4G17100

6 of 13

Yes

Atha\AT4G35335

6 of 13

Atha\FH3

6 of 13

Yes

Atha\NRPD4

6 of 13

Yes

Atha\MYA1

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPAC26H5.05

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Camta. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

CAMTA1; calmodulin binding transcription activator 1

model of nonprogressive cerebellar ataxia with mental retardation

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CAMTA2; calmodulin binding transcription activator 2

11 of 14

611508

CAMTA1; calmodulin binding transcription activator 1

10 of 14

611501

CEREBELLAR DYSFUNCTION WITH VARIABLE COGNITIVE AND BEHAVIORAL ABNORMALITIES; CECBA

nonprogressive cerebellar ataxia with mental retardation

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Show neighbor-neighbor interactions:

Off

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

Select Layout:

Force Directed

Circle

Concentric

Legend:

Protein

RNA

Selected Interactor(s)

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Camta

pull down, western blot

(Gong et al., 2007)

Camta - Deaf1

two hybrid array

(Shokri et al., 2019)

Camta - NC2α

two hybrid array

(Shokri et al., 2019)

Camta - pzg

two hybrid array, bimolecular fluorescence complementation, fluorescence microscopy

(Shokri et al., 2019)

Camta - sqz

two hybrid array

(Shokri et al., 2019)

Summary of Genetic Interactions

esyN Network Diagram

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

esyN Network Key:

Suppression

Enhancement

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

enhanceable

(Han et al., 2006)

suppressible

(Han et al., 2006)

suppressible

(Han et al., 2006)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Arr2

enhanceable

Camta

(Han et al., 2006)

External Data

Linkouts

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-60

Cytogenetic map

45D8-45E1

Sequence location

2R:9,446,046..9,480,076 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

45D8-45E1

Limits computationally determined from genome sequence between P{lacW}wun^k09507&P{lacW}l(2)k12402^k12402 and P{EP}EP2165&P{lacW}l(2)k01301^k01301

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

45E-45E

(determined by in situ hybridisation)

(Yokokura et al., 1995)

Experimentally Determined Recombination Data

Location

2-60

(FlyBase, 2016)

2-59.1

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (61)

Aberrations including deletions of this gene Aberrations including duplications of this gene

FlyORF

F004817

M{UAS-Camta.ORF-VN}ZH-86Fb

F000702

M{UAS-Camta.ORF.3xHA.GW}ZH-86Fb

Korea

12605

P{VT014097-GAL4}attP2

13403

P{VT014093-GAL4}attP2

15058

P{VT014095-GAL4}attP2

15059

P{VT014099-GAL4}attP2

15925

P{GMR93G05-lexA}JK22C

8809R-1

8809R-4

v106025

v107270

v318590

PBac{fTRG00536.sfGFP-TVPTBF}VK00033

More stocks available...

Genomic Clones (30)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (19)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD15680

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Sato et al., 2019)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Isolated in a screen for aberrant courtship song.

(Yokokura et al., 1995)

Mutant males are characterised by low mating success, aberrant courtship song patterns and poor flying ability.

(Yokokura et al., 1995)

Relationship to Other Genes

Source for database merge of

Source for merge of: Camta cro

(Sato et al., 2019)

Source for merge of: Camta CG13952 CG13953

(FlyBase Genome Annotators, 2008)

Additional comments

Annotations CG8809, CG13952 and CG13953 merged as CG42332 in release 5.9 of the genome annotation.

(FlyBase Genome Annotators, 2008)

Nomenclature History

Source for database identify of

Source for identity of: Camta CG8809

(Bouche, 2002.4.2)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (14)

Reported As

Symbol Synonym

CG13952

(Keleman et al., 2009.8.5, Markstein et al., 2008, Han et al., 2006)

CG13953

(Keleman et al., 2009.8.5, Han et al., 2006)

CG42332

(National Institute of Genetics Fly Stocks, 2022-, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Perkins et al., 2009.3.31, FlyBase Genome Annotators, 2008)

CG8809

(Keleman et al., 2009.8.5, Bouche, 2002.4.2)

Camta

(Fisher et al., 2023, Pang et al., 2021, Knudsen et al., 2020, Chai et al., 2019, Gaspar et al., 2019, Sato et al., 2019, Shokri et al., 2019, Bischof et al., 2018, Hall et al., 2018, Transgenic RNAi Project members, 2017-, Mishra et al., 2016, Sarov et al., 2016, Schwartz et al., 2016, Gene Disruption Project members, 2015-, Schertel et al., 2015, Ashwal-Fluss et al., 2014, Toshima et al., 2014, Georgiev et al., 2012, Japanese National Institute of Genetics, 2012.5.21)

DmCAMTA

(Bouche, 2002.4.2, Bouche et al., 2002)

camta

(Mishra et al., 2021, Loedige et al., 2015, Greil et al., 2003)

cro

(Sato et al., 2019)

dCAMTA

(Gong et al., 2007, Han et al., 2007, Han et al., 2006)

tes

(Vuong-Brender et al., 2021)

Name Synonyms

CG13952

CG13953

CG42332

(FlyBase Genome Annotators, 2008)

Calmodulin-binding transcription activator

(Bouche, 2002.4.2, Bouche et al., 2002)

Calmodulin-binding transcription factor

(Sato et al., 2019, Eddison et al., 2012)

Camta

(Toshima et al., 2014)

calmodulin-binding transcription activator

(Han et al., 2006)

croaker

(Sato et al., 2019, Gleason, 2005, Yokokura et al., 1995)

Secondary FlyBase IDs

FBgn0020554
FBgn0259234
FBgn0033417
FBgn0033415
FBgn0033416

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 56 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

35974

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

B7YZU4

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

B7YZU4

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35974/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0287478

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0287478

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG42332

MARRVEL_MODEL - MARRVEL (model organism gene)

35974

Linkouts

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0259234

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0287478

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

References (82)

The following external sites may use different assemblies or annotations than FlyBase.

-0.74

Report Sections