FB2025_02 , released April 17, 2025
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Hem, SCAR
FlyBase ID
FBig0000018482
Interaction Network
Interactions Browser links
Hem network
SCAR network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0216499-2.CH.WB
Reference
Stephan et al., 2011
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
SCAR 

WAVE

neutral component
SCAR 

WAVE

neutral component
SCAR 

WAVE

neutral component
Hem 

Kette

neutral component
Hem 

Kette

neutral component
Hem 

Kette

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; proteins derived from adult head extract.

(Stephan et al., 2011)

A large fraction of Abi cofractionates with SCAR and the WAVE complex subunit Hem in protein complexes of about 400-500 kDa.

(Stephan et al., 2011)
FBrf0218395-9517.DPiM
Reference
Guruharsha et al., 2011
Description
physical association
Assay
Collection
DPiM-2
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Hem 
unspecified role
Hem 
unspecified role
Hem 
unspecified role
SCAR 
unspecified role
SCAR 
unspecified role
SCAR 
unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

HGScore = 70.91732

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)