Open Close
General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000095048
Interaction Network
Interactions Browser links
mxc network
Spt6 network
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0213662-2.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mxc 

MPM-2

bait
Spt6 

Spt6

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

The MPM-2 antibody, raised against human mitotic phosphoproteins, marks the histone locus body (HLB) during the S phase of Drosophila cells and reacts with phosphorylated mxc among other proteins.

Spt6 may coimmunoprecipitate with the MPM-2 antibody because it reacts with mxc and/or some other MPM-2-reactive HLB protein.

Spt6 and mxc colocalize at the HLB during S phase.

Bait endogenous to nuclear extract.

Prey endogenous to nuclear extract.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)