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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000096860
Interaction Network
Interactions Browser links
sicily network
Hsp83 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0221023-5.coIP.MS
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sicily
bait
mCherry tag
Hsp90
prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
Source was adults of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.
Tagged sicily immunoprecipitated using RFP nanobodies.
FBrf0221023-6.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sicily
bait
V5 tag
Hsp90
prey
GFP tag
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.
Reductions in Hsp83 activity (by RNAi or the inhibitor geldanamycin) reduce the level of sicily protein.
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)