Open Close
General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000098014
Interaction Network
Interactions Browser links
Spt5 network
msl-1 network
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0220177-1.PD.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Spt5 

SPT5

bait

MBP tag

Spt5 
Spt5 

MSL1

prey

GST label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
PEHE domain
sufficient binding region
aa 751-1039
Spt5 
N-terminal region
sufficient binding region
aa 112-393
Spt5 
middle region
sufficient binding region
aa 389-733
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey as a recombinant fusion protein in bacterial system.

Purified msl-1 PEHE domain interacts with N-terminal or middle fragments of Spt5.

Attempts to purify intact msl-1-containing MSL complex did not recover Spt5.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)