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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000102495
Interaction Network
Interactions Browser links
Antp network
MED19 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0224861-12.PD.A
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Med19
bait
GST tag
Antp 
Antp
prey
[35]S label
Antp 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Antp 
homeodomain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.
MED19 can discriminate between different homeodomains. GST-MED19 pulled down Antp, Dfd, Ubx and Abd-B homeodomain peptides, but not en or hth peptides.
FBrf0224861-8.PD.A
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Antp 
Antp
bait
GST tag
Antp 
Med19
prey
[35]S label
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Antp 
homeodomain
sufficient binding region
aa 279-378
homeodomain-interacting motif (HIM)
sufficient binding region
aa 155-229
\'HIM\'
homeodomain-interacting motif (HIM)
necessary binding region
aa 160-229
\'ΔHIM\'
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)