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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000102495
Interaction Network
Interactions Browser links
MED19 network
Antp network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0224861-12.PD.A
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

Med19

bait

GST tag

Antp 

Antp

prey

[35]S label

Antp 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Antp 
homeodomain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

MED19 can discriminate between different homeodomains. GST-MED19 pulled down Antp, Dfd, Ubx and Abd-B homeodomain peptides, but not en or hth peptides.

FBrf0224861-8.PD.A
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Antp 

Antp

bait

GST tag

Antp 

Med19

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Antp 
homeodomain
sufficient binding region
aa 279-378
homeodomain-interacting motif (HIM)
sufficient binding region
aa 155-229

\'HIM\'

homeodomain-interacting motif (HIM)
necessary binding region
aa 160-229

\'ΔHIM\'

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)