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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000103513
Interaction Network
Interactions Browser links
nSyb network
Syt4 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0211928-9.PBD
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
nSyb 

n-syb

neutral component
nSyb 

n-syb

neutral component
nSyb 

n-syb

neutral component
Syt4 

SYT4

neutral component
Syt4 
Syt4 

SYT4

neutral component
Syt4 

SYT4

neutral component
Syt4 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Syt4 
cytoplasmic domain
sufficient binding region
aa 134-474
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

nSyb bearing v-SNARE vesicles contain a lipid-bound fluorescence resonance energy transfer donor-acceptor pair. When v-SNARE vesicles fuse to t-SNARE vesicles (bearing Syx1A and Snap25), the donor-acceptor pair is diluted, resulting in dequenching of the fluorescence signal.

Interaction in vitro; proteins produced as a recombinant fusion proteins in bacterial system.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)