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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000104642
Interaction Network
Interactions Browser links
mir-184 network
Gli network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0208499-2.miR-mRNA.LUC
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

mir-184

bait
Gli 

Gli

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line; bait produced from endogenous gene; prey produced from transfected reporter construct.

luciferase reporter assay

FBrf0216115-13.miR-mRNA.LUC
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

miR-184

bait
Gli 

Gli

prey
Gli 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Gli 
3-prime UTR
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

Luciferase reporter assay.

FBrf0231586-1.miR-mRNA.IHC
Description
physical association
Collection
Cell line used
Participants
Corresponds to
Reported as
Role
Note

mir-184

bait
Gli 

Gli

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval wing discs of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

Overexpression of mir-184 reduces Gli protein levels.

FBrf0231586-5.miR-mRNA.IHC
Description
physical association
Collection
Cell line used
Participants
Corresponds to
Reported as
Role
Note

mir-184

bait
Gli 

Gli

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larval wing discs of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

Overexpression of mir-184 sponge increases Gli protein levels.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)