FB2025_01 , released February 20, 2025
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
lark, rho
FlyBase ID
FBig0000108227
Interaction Network
Interactions Browser links
lark network
rho network
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0233521-7.PD.PCR
Reference
Swain et al., 2016
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
lark 

Lark

bait

His tag

lark 
rho 

rho

prey
rho 
rho 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
lark 
RRM1-RRM2-ZnF
sufficient binding region
aa 1-211

coordinates relative to lark-PA

rho 
region 1
sufficient binding region
GCGACUCGAAACUGAAAUUGAAACUGAAAGAAAGAAAUAUUCAAAUUGUCGUGUGUGUGG

"rho-1" construct

rho 
region 2
sufficient binding region
CACAAAAGCAACAACGGUGCGUGUGUGCAAUGCGACUUGAGG

"rho-2" construct

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro transcription.

(Swain et al., 2016)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)