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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000109505
Interaction Network
Interactions Browser links
His3 network
tbrd-2 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0235256-6.PD.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
His3 

His3

bait

coupled to beads

His3 

tbrd-2

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
His3 
interaction domain
sufficient binding region
aa 1-22aa 14-33aa 23-42
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait peptides synthesized in vitro; prey produced as a recombinant fusion protein in bacterial system.

His3 peptides acetylated at K9 and K14, K18 and K23, or K27 and K36 bound tbrd-2 more weakly than unmodified versions.

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References (1)