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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000111563
Interaction Network
Interactions Browser links
SPR network
Mip network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0210504-1.PH
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
SPR 

SPR

unspecified role
SPR 

SPR

unspecified role
SPR 

SPR

unspecified role
Mip 

MIP

unspecified role
Mip 
Mip 
Mip 

MIP

unspecified role
Mip 

MIP

unspecified role
Mip 
Mip 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Mip 
interaction domain
sufficient binding region
aa 66-74aa 67,74

coordinates relative to Mip-PA, AWQSLQSSW

coordinates relative to Mip-PA, AWAAAAAAW

Mip 
interaction domain
mutation disrupting interaction
aa 67,74

coordinates relative to Mip-PA, AAQSLQSSA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in CHO cell system; ligand peptide synthesized in vitro; receptor produced from transfected construct.

Interaction inferred based on Mip\'s ability to induce increase in [Ca2+] through SPR in a heterologous system.

FBrf0247343-2.PBD
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
SPR 

SPR

unspecified role
SPR 
SPR 
SPR 

SPR

unspecified role
SPR 
SPR 
SPR 

SPR

unspecified role
Mip 

MIP

unspecified role
Mip 

MIP

unspecified role
Mip 

MIP

unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
SPR 
interaction domain residue 224
mutation decreasing interaction
aa 224

F224L, coordinates relative to SPR-PA

SPR 
interaction domain residue 229
mutation decreasing interaction
aa 229

P229T, coordinates relative to SPR-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in CHO cell system; ligand peptide produced commercially; receptor produced from transfected construct.

Interaction inferred from the ability of ligand peptide to induce a phenotype in a heterologous system expressing the receptor.

External Crossreferences and Linkouts ( 0 )
References (2)