Open Close
General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000116745
Interaction Network
Interactions Browser links
mir-210 network
SoxN network
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0239602-2.miR-mRNA.LUC
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

miR-210

bait
SoxN 

SoxN

prey
SoxN 
SoxN 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
SoxN 
3-prime UTR
sufficient binding region
SoxN 
mir-210 target site
mutation decreasing interaction
AUACGCACAC

AUACGCACAC > AAACCUAUUC

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Luciferase reporter assay.

Source was S2R+ cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

FBrf0239602-4.miR-mRNA.PCR
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

mir-210

bait
SoxN 

SoxN

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult brains of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

Overexpression of mir-210 reduces SoxN mRNA levels.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)