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General Information
Name
DGRP_wild_type_strains
Species
D. melanogaster
Reagent type
FlyBase ID
FBlc0000504
Vector
    Title
    A set of inbred wild-type strains derived from a single natural population.
    Accessions
      Overview
      Description

      Collection of 192 (originally 168) fully sequenced inbred lines derived from a single natural population; available for analysis of quantitative traits and population genomics. A website is maintained that allows community access to a number of analyses using these strains.

      Available from
      [DGRP stocks at BDSC](https://bdsc.indiana.edu/stocks/wt/dgrp.html).
      Biosample Source
      Overview
      Strain
      Stage
      Sex
      Tissue isolated
      Other tissues studied
      Cell component
      Cell line
      Key genes
      Methods
      Sample preparation
      Reagent Details
      Methods
      Protocol

      Mated females were collected from a population in Raleigh, North Carolina, USA; the progeny of each female were inbred via full-sibling matings for 20 generations. Genomic sequence of 168 of the inbred lines was determined using Illumina and/or 454 sequencing technology; sequence reads were mapped to the D. melanogaster reference genome (iso-1 strain).

      Mode of Assay
      Data analysis

      4,672,297 single nucleotide polymorphisms (SNPs) were called using the Joint Genotyper for Inbred Lines (JGIL), which takes into account coverage and quality sequencing statistics, and expected allele frequencies after 20 generations of inbreeding from an outbred population initially in Hardy–Weinberg equilibrium. In cases where base calls were made by both technologies, concordance was 99.36%.

      Comments
      Associated Data
      Size
      Associated strains
      219 Strain(s)
      Files
      Additional Information

      [HGSC-DGRP](https://www.hgsc.bcm.edu/arthropods/drosophila-genetic-reference-panel)

      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      DGRP_wild_type_strains
      Drosophila Genetic Reference Panel
      Drosophila melanogaster Genetic Reference Panel
      Raleigh lines
      Name Synonyms
      A set of inbred wild-type strains derived from a single natural population.
      Secondary FlyBase IDs
        References (9)