A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Reference Report

Reference
Citation Racine, R.R., Langley, C.H., Voelker, R.A. (1980). Enzyme mutants induced by low-dose-rate gamma-irradiation in Drosophila: frequency and characterization.  Environ. Mutagen. 2(2): 167--177.
FlyBase ID FBrf0034635
Type of publication Research paper
Offprint Available Yes
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PubMed ID 6799288
PubMed Abstract One thousand lines of a balanced lethal strain of Drosophila melanogaster heterozygous at seven allozyme loci were subjected to chronic (0.15 rad/min) gamma-irradiation (137Cs). After 15 generations of exposure they were screened by gel electrophoresis for newly arisen null mutants and/or mobility variants. Seven independent nulls were recovered. 1) None were associated with a cytogenetically detectable aberration; 2) one of six analyzed was associated with recessive lethality, suggesting association with a submicroscopic interlocus deficiency; 3) three of five which could be analyzed for cross-reacting material (CRM) production were CRM-positive; and 4) two of six produced an active heterodimer with an active normal allele. The results taken together suggest that most of the mutations are point mutations rather than small deficiencies.
Biosis 71045090
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Language of publication English
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Abbreviation Environ. Mutagen.
Title Environmental Mutagenesis
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Volume range 1-9
Year range 1979-1987
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Place of publication New York
Language of publication English
ISBN/ISSN 0192-2521
CODEN ENMUDM
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