Reference Report

Reference
Citation	Kerridge, S. (1981). Distal into Proximal (Dipr): A homoeotic mutation of Drosophila melanogaster. Mol. Gen. Genet. 184(3): 519--525. (Export to RIS)
FlyBase ID	FBrf0037077
Publication Type	Research paper
PubMed ID	6801435
PubMed Abstract	The morphology and genetical characteristics of a new dominant homoeotic mutation, called Distal into proximal (Dipr), are described. Dipr causes two main abnormalities, both of which are specific to distal regions of the adult appendages (i.e. the wing, haltere, legs, antenna, and proboscis); first that distal parts are reduced in size and second that the patterns found distally resemble those normally localised in more proximal parts. The mutation maps to the right arm of chromosome 3 and is associated with an inversion with breakpoints in 84D and 84F. Analysis of revertants of Dipr show that the right breakpoint of In(3R)Dipr is the one responsible for the mutant phenotype. Complementation analyses of Dipr revertants and dosage studies of Dipr with different doses of Dipr+ indicate that the mutant is a hypermorph affecting the normal expression of a gene localised in 84F. The developmental significance of the mutation is discussed.
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Mol. Gen. Genet.
Title	Molecular and General Genetics
Publication Year	1967-2001
ISBN/ISSN	0026-8925
Data from Reference
Aberrations (15)
	Df(3R)Antp17 Df(3R)dsx2D Df(3R)dsx5 Df(3R)p13 Dp(3;3)Antp^73b-rv8 Dp(3;Y)P92 In(3R)rn^Dipr+R1 In(3R)rn^Dipr+R2 In(3R)rn^Dipr+R4 In(3R)rn^Dipr+R5 In(3R)rn^Dipr+R7 In(3R)rn^Dipr+R8 In(3R)rn^Dipr+R9 In(3R)rn^Dipr T(2;3)rn
Alleles (11)
	Dipr¹ Dipr^+R1 Dipr^+R2 Dipr^+R4 Dipr^+R5 Dipr^+R7 Dipr^+R8 Dipr^+R9 rn¹ rn³ rn^Dipr
Genes (4)
	cu Dipr rn th