|Citation||Struhl, G. (1982). Spineless-aristapedia: a homeotic gene that does not control the development of specific compartments in Drosophila. Genetics 102(): 737--749. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||A two-step screen for isolating null mutations of the spineless-aristapedia locus has been performed, and several amorphic mutations, as well as a small deficiency, have been obtained. With the exception of the deficiency, which deletes genes required for viability on either side of the spineless-aristapedia locus, these mutations result in a transformation of only the distal antenna into distal leg, thereby indicating that the spineless-aristapedia gene is required for specifying antennal as opposed to leg development in only the distal portion of the antenna. Because this distal region does not appear to be a developmental compartment, it is probable that the spineless-aristapedia gene, unlike several other homeotic genes, is required for maintaining the correct determined state in a population of cells defined by their relative position, not by their ancestry.|
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|Language of Publication||English|
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