A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Reference Report

Reference
Citation Levis, R.W., Bingham, P.M., Rubin, G.M. (1982). Physical map of the white locus of Drosophila melanogaster.  Proc. Natl. Acad. Sci. USA 79(2): 564--568.
FlyBase ID FBrf0038648
Type of publication Research paper
Offprint Available Yes
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PubMed ID 6281775
PubMed Abstract The white locus of Drosophila melanogaster is a genetically well-characterized locus, mutations in which alter the degree of pattern of pigmentation of the eyes. Using a previously cloned DNA segment containing a portion of the white locus of a mutant allele, we have cloned and characterized the DNA of a 48-kilobase chromosomal region of the Canton S wild-type strain. We have mapped the positions, relative to restriction endonuclease cleavage sites, of several previously characterized chromosomal rearrangement breakpoints that bracket the while locus. These results define a segment of 14 kilobase that contains all of the white locus sequences necessary for the production of a wild-type eye color phenotype. By conventional criteria, no repetitive sequences are present within this 14-kilobase segment; however, we have identified an extremely weak DNA sequence homology between a portion of this segment and a chromosomal region in the vicinity of the zeste locus.
Biosis 73082819
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Language of publication English
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Abbreviation Proc. Natl. Acad. Sci. USA
Title Proceedings of the National Academy of Sciences of the United States of America
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Volume range 1-
Year range 1915-
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Place of publication Washington, DC
Language of publication English
ISBN/ISSN 0027-8424
CODEN PNASA6
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