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Citation
Scavarda, N.J., O'Tousa, J., Pak, W.L. (1983). Drosophila melanogaster locus with gene dosage effects on rhodopsin.  Proc. Natl. Acad. Sci. U.S.A. 80(14): 4441--4445.
FlyBase ID
FBrf0040131
Publication Type
Research paper
Abstract

Mutations that decrease the amplitude of the prolonged depolarizing afterpotential (PDA) in Drosophila melanogaster have been shown to have reduced rhodopsin content in the rhabdomeres of photoreceptor cells. In the present study, a genetic analysis of a class of third chromosome PDA-defective mutants localized the ninaE locus to the salivary band region 92A-B. In flies with only one copy of this region instead of the normal two copies, and in ninaE heterozygotes, the rhodopsin content of the major class of photoreceptors is reduced. Three doses of this region increase the rhodopsin content of these photoreceptors. These characteristics of the ninaE locus are expected of the structural gene encoding the major species of opsin in the Drosophila compound eye.

PubMed ID
PubMed Central ID
PMC384054 (PMC) (EuropePMC)
DOI
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Proc. Natl. Acad. Sci. U.S.A.
    Title
    Proceedings of the National Academy of Sciences of the United States of America
    Publication Year
    1915-
    ISBN/ISSN
    0027-8424
    Data From Reference
    Aberrations (7)
    Alleles (5)
    Genes (2)