A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Gundelfinger, E.D., Di Carlo, M., Zopf, D., Melli, M. (1984). Structure and evolution of the 7SL RNA component of the signal recognition particle.  EMBO J. 3: 2325--2332. (Export to RIS)
FlyBase ID FBrf0040773
Publication Type Research paper
PubMed ID 6209132
PubMed Abstract We have cloned and characterized cDNA copies of larval and adult Drosophila 7SL RNA. The Drosophila 7SL sequence shares 66.3% homology with that of human 7SL RNA. The homology is not evenly distributed along the sequence, but is concentrated in blocks in the central part of the molecule. We have analysed the secondary structure of Drosophila and human 7SL RNA free in solution by digestion with single and double strand specific nucleases. Similar experiments with the 7SL RNA bound to proteins within the signal recognition particle show essentially the same digestion pattern. A model of the secondary structure common to Drosophila and human 7SL RNA is presented.
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Language of Publication English
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Publication Type Journal
Abbreviation EMBO J.
Title The EMBO Journal
Publication Year 1982-
ISBN/ISSN 0261-4189
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