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| Citation | Knipple, D.C., MacIntyre, R.J. (1984). Cytogenetic mapping and isolation of mutations at the -Gal-1 locus of Drosophila melanogaster. Molec. gen. Genet. 198: 75--83. |
| FlyBase ID | FBrf0041503 |
| Type of publication | Research paper |
| Offprint Available | No |
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| PubMed ID | 6441104 |
| PubMed Abstract | The structural gene beta-Gal-1 encoding a beta-galactosidase (EC 3.2.1.23) of Drosophila melanogaster has been mapped by two independent genetic approaches. In the first, gene dosage dependent variation in beta-galactosidase activity levels in segmental aneuploids, generated from crosses of Y-autosome translocation stocks, was determined quantitatively. A dosage sensitive region on the left arm of chromosome 2 was identified and mapped to region 26A7-9. In the second approach, two null activity variants were isolated from wild populations. It was shown by deletion analysis that these nulls map to the same region as that determined by the segmental aneuploidy method. The results of an EMS mutagenesis screen showed that, besides the beta-Gal-1 locus, there are four loci defined by recessive lethal mutations which map in the 26A7-9 region. |
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| Secondary IDs | |
| Language of publication | English |
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| Abbreviation | Molec. gen. Genet. |
| Title | Molecular and General Genetics |
| Authors | |
| Volume range | 99-264 |
| Year range | 1967-2001 |
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| Place of publication | Berlin |
| Language of publication | English |
| ISBN/ISSN | 0026-8925 |
| CODEN | MGGEAE |
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Data from Reference
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| Aberrations (79)
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| Alleles (29)
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| Genes (5)
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