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| Citation | Muller-Holtkamp, F., Knipple, D.C., Seifert, E., Jaeckle, H. (1985). An early role of maternal mRNA in establishing the dorsoventral pattern in pelle mutant Drosophila embryos. Dev. Biol. 110(): 238--246. (Export to RIS) | ||
| FlyBase ID | FBrf0042358 | ||
| Publication Type | Research paper | ||
| PubMed ID | 2408942 | ||
| PubMed Abstract | Mutations of the maternal effect locus pelle (pll) cause dorsalized Drosophila embryos. In extreme mutants, the embryo develops into a long hollow tube of dorsal cuticular structures with no sign of ventral pattern elements. Injection of wild-type cytoplasm or poly(A)+RNA into mutant pll embryos partially restores the normal pattern. Rescuing activity is present in the wild-type cytoplasm until the late blastoderm stage, but is already absent from the poly(A)+RNA fraction by the time of pole cell formation. At the same time, pll embryos fail to respond to injected biologically active poly(A)+RNA. This indicates that pll+ mRNA is lost early from the pool of maternal RNA and that there is a non-RNA component of rescue. This component, most likely the pll+ protein, appears to be unequally distributed in wild-type embryos. | ||
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| FB2013_03 | |||
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| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Dev. Biol. | ||
| Title | Developmental Biology | ||
| Publication Year | 1959- | ||
| ISBN/ISSN | 0012-1606 | ||
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Data from Reference
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| Alleles (10)
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| Genes (1)
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