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Citation
Cabrera, C.V., Martinez Arias, A., Bate, M. (1987). The expression of three members of the achaete-scute gene complex correlates with neuroblast segregation in Drosophila.  Cell 50(): 425--433.
FlyBase ID
FBrf0045761
Publication Type
Research paper
Abstract

The expression of a subset of homologous genes of the AS-C is required during embryogenesis and metamorphosis for proper neural development. Here we study the expression of three of these genes (T3, T4, and T5) and show that their transcripts accumulate at the blastoderm stage in periodic patterns coincident with the dorsoventral extent of the neuroectoderm. Subsequent expression is in partially overlapping patterns that correlate with the segregation of neuroblasts. These genes are not transcribed in neurons. We also show that a deficiency for the AS-C prevents the appearance of at least one identified class of neuroblasts. We propose that the AS-C is part of a network of genes responsible for the segregation of neuroblasts.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell
    Title
    Cell
    Publication Year
    1974-
    ISBN/ISSN
    0092-8674
    Data From Reference
    Aberrations (2)
    Genes (3)