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Citation
Sunkel, C.E., Whittle, J.R.S. (1987). Brista: A gene involved in the specification and differentiation of distal cephalic and thoracic structures in Drosophila melanogaster.  Rouxs Arch. Dev. Biol. 196(): 124--132.
FlyBase ID
FBrf0047276
Publication Type
Research paper
Abstract

A gene Brista has been identified in chromosome 2R, in the region 60D11-E4, in which mutations cause homoeotic transformation of distal antennal structures to distal leg derivatives, and in which certain alleles also lead to upsets in the formation of distal elements of the legs. This gene is haploinsufficient for the homoeotic phenotype. Several putative null and two hypomorphic alleles have been recovered. The effects of exposure to the non-permissive temperature of a temperature-sensitive allele are cummulative and depend upon the length of the exposure during the period of antennal cell proliferation. It is suggested that this gene contributes to the stability of the state of determination in distal domain of the antennal and leg discs, and its relationship to other genes with similar mutant phenotype is discussed.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Rouxs Arch. Dev. Biol.
    Title
    Roux's Archives of Developmental Biology
    Publication Year
    1975-1996
    ISBN/ISSN
    0930-035X
    Data From Reference
    Aberrations (12)
    Alleles (8)
    Genes (2)