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Citation
Frei, E., Schuh, R., Baumgartner, S., Burri, M., Noll, M., Jurgens, G., Seifert, E., Nauber, U., Jackle, H. (1988). Molecular characterization of spalt, a homeotic gene required for head and tail development in the Drosophila embryo.  EMBO J. 7(1): 197--204.
FlyBase ID
FBrf0047929
Publication Type
Research paper
Abstract

The isolation, identification and structure of the spalt gene is described. This novel homeotic gene of Drosophila is required for the establishment of the posterior-most head and the anterior-most tail segments of the embryo. It encodes a small mRNA of 0.8 kb which is under the control of over 15 kb of upstream sequences as indicated by the phenotype of transformed embryos. The putative spalt protein contains internal repeats and other interesting structural motifs but no homeo box. The spalt transcript accumulates motifs but no homeo box. The spalt transcript accumulates to high levels in the segmental anlagen affected in mutant embryos but is also found in regions of the embryo where no functional requirement has been demonstrated.

PubMed ID
PubMed Central ID
PMC454251 (PMC) (EuropePMC)
DOI
Associated Information
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    EMBO J.
    Title
    The EMBO Journal
    Publication Year
    1982-
    ISBN/ISSN
    0261-4189
    Data From Reference
    Aberrations (4)
    Alleles (7)
    Genes (3)
    Molecular Constructs (3)
    Transgenic Constructs (3)