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Reference Report
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| Citation | Dowse, H.B., Dushay, M.S., Hall, J.C., Ringo, J.M. (1989). High-resolution analysis of locomotor activity rhythms in disconnected, a visual system mutant of Drosophila melanogaster. Behav. Genet. 19(4): 529--542. (Export to RIS) | ||
| FlyBase ID | FBrf0049221 | ||
| Publication Type | Research paper | ||
| PubMed ID | 2508614 | ||
| PubMed Abstract | Free-running locomotor activity and eclosion rhythms of Drosophila melanogaster, mutant at the disconnected (disco) locus, are substantially different from the wild-type phenotype. Initial periodogram analysis revealed little or no rhythmicity (Dushay et al., 1989). We have reanalyzed the locomotor activity data using high-resolution signal analysis (maximum-entropy spectral analysis, or MESA). These analyses, corroborated by autocorrelograms, uncovered significant residual circadian rhythmicity and strong ultradian rhythms in most of the animals tested. In this regard the disco mutants are much like flies expressing mutant alleles of the period gene, as well as wild-type flies reared throughout life in constant darkness. We hypothesize that light normally triggers the coupling of multiple ultradian oscillators into a functional circadian clock and that this process is disrupted in disco flies as a result of the neural lesion. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Behav. Genet. | ||
| Title | Behavior Genetics | ||
| Publication Year | 1970- | ||
| ISBN/ISSN | 0001-8244 | ||
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Data from Reference
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| Alleles (3)
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| Genes (1)
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