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Reference
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| Citation |
Oro, A.E., Umesono, K., Evans, R.M. (1989). Steroid hormone receptor homologs in development. Kay, Smith, 1989 : 133--140.
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| FlyBase ID |
FBrf0049538 |
| Type of publication |
Review |
| Offprint Available |
No |
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External Crossreferences
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| PubMed ID |
2699853 |
| PubMed Abstract |
The steroid/thyroid receptor superfamily are ligand-dependent transcription factors which consist of distinct functional domains
required for transcriptional control of a network of genes. Members of this superfamily are beginning to be studied for their
contribution to embryogenesis. Two human receptors for the vertebrate morphogen retinoic acid have been isolated and further
characterized on model promoters. Moreover, the presence of homologs of these receptors in Drosophila reveals that members
of this superfamily predate the divergence of the vertebrates and invertebrates. One locus is knirps-related (knrl), whose
product is closely related to that of the gap segmentation gene knirps (kni). knrl is one of the most diverged steroid receptor-like
molecules and displays a spatially restricted blastoderm pattern.
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Associated Information
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| Comments |
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| Text of personal communication |
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Related Publications
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Also Published As
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Other Reference Information
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| Secondary IDs |
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| Language of publication |
English |
| Additional language(s) of abstract |
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| ISBN |
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Published In
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| Abbreviation |
Kay, Smith, 1989 |
| Title |
The molecular basis of positional signalling. |
| Authors |
Kay, R., Smith, J. |
| Volume range |
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| Year range |
1989 |
| Page range |
186pp |
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| Place of publication |
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| Language of publication |
English |
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| CODEN |
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Data from Reference
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| Aberrations (2)
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| Alleles (1)
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| Genes (4)
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